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1.
J Pharm Bioallied Sci ; 16(Suppl 2): S1453-S1455, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38882781

ABSTRACT

Background: Nature has given us an enormous number of medicines for every disease that affects people. Aim: To compare the antimicrobial efficacy of an herbal and 0.2% chlorhexidine gluconate mouthrinse against Streptococcus mutans, Staphylococcus aureus, and Enterococcus faecalis. Materials and Methods: The antimicrobial effectiveness (zone of inhibition) of a herbal mouthrinse and 0.2% chlorhexidine mouthrinse were determined by agar well-diffusion method. Results: At 50% concentration, the experimental mouthrinse inhibits the growth of Streptococcus mutans, Staphylococcus aureus, and Enterococcus faecalis. Conclusion: Against the three strains, chlorhexidine mouthrinse (0.2%) performs better in terms of antimicrobial effectiveness.

2.
J Pharm Bioallied Sci ; 13(Suppl 2): S1029-S1032, 2021 Nov.
Article in English | MEDLINE | ID: mdl-35017923

ABSTRACT

AIM: The aim of the current survey was conducted to assess the knowledge, attitude, and awareness regarding orthognathic surgery among orthodontic patients. MATERIALS AND METHODS: This is cross-sectional web-based questionnaire survey conducted among orthodontic patients in Tamil Nadu. The self-administered questions related to awareness of orthognathic surgery were collected from 500 subjects. The statistical analysis was done using the Statistical Package for the Social Sciences (V 22.0). The frequency distribution was computed. RESULTS: This survey revealed that 466 (93.2%) respondents had awareness about the role of orthognathic surgery. 332 (66.4%) had given the correct responses related to differentiating skeletal and dental malocclusion, 454 (90.6%) had the awareness of risk factors associated with orthognathic surgery and 40 (7.0%) were experienced regarding the procedure. CONCLUSION: The result of the current study showed that it clearly implies that the population was aware of orthognathic surgery as a treatment modality for correcting skeletal deformities.

3.
J Pharm Bioallied Sci ; 13(Suppl 2): S1174-S1177, 2021 Nov.
Article in English | MEDLINE | ID: mdl-35017951

ABSTRACT

AIM: To evaluate the levels of leptin in gingival crevicular fluid (GCF) during orthodontic tooth movement and to find the role of leptin as a mediator for tooth movement. MATERIALS AND METHODS: GCF was collected from 25 subjects and the levels of leptin in it were measured. Sample (A) pretreatment, (B) 6 h after applying retractive orthodontic force from right side canine, (C) without retractive force from left side canine, and after 21 days from right canine (D), and left canine (E). RESULTS: GCF Leptin concentration in pretreatment, 6 h control and 21st day control were all similar. GCF leptin concentration at 6 h test tooth site was increased which was statistically significant. GCF leptin concentration in 21st day test tooth was decreased only a little than the control tooth which shows statistically no difference. CONCLUSION: Leptin is one of the mediators of orthodontic tooth movement.

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