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J Biol Phys ; 44(4): 579-590, 2018 12.
Article in English | MEDLINE | ID: mdl-29968194

ABSTRACT

In this paper, radiation shielding parameters such as mass attenuation coefficients and half value layer (HVL) of some antioxidants are investigated using MCNPX (version 2.4.0). The validation of the generated MCNPX simulation geometry for antioxidant structures is provided by comparing the results with standard WinXcom data for radiation mass attenuation coefficients of antioxidants. Very good agreement between WINXCOM and MCNPX was obtained. The results from the validated geometry were used to calculate the shielding parameters of different antioxidants. The radiation attenuation properties of each antioxidant were compared with each other. The results showed that, on average, the highest and the lowest radiation mass attenuation coefficients were observed on hesperidin and delphinidin chloride, respectively. It can be concluded that Monte Carlo simulation is a strong tool and an alternate method where experimental investigations are not possible and a standard simulation setup can be used in further studies for different biological structures. It can also be concluded that the obtained results from this study are very useful for radiology and radiotherapy applications where antioxidants are frequently used.


Subject(s)
Antioxidants/chemistry , Computer Simulation , Monte Carlo Method , Radiation Protection/methods , Software , Anthocyanins/chemistry , Anthocyanins/pharmacology , Antioxidants/pharmacology , Hesperidin/chemistry , Hesperidin/pharmacology , Humans , Scattering, Radiation
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