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1.
Genome Announc ; 2(1)2014 Jan 30.
Article in English | MEDLINE | ID: mdl-24482525

ABSTRACT

Bacillus sp. strain CPSM8 is an efficient solubilizer and mineralizer of phosphorus. Here, we present the 4.39-Mb draft genome sequence of the strain, providing insight into the phosphorus-releasing genes related to productivity in aquatic habitats.

2.
Virusdisease ; 25(1): 1-17, 2014 Jan.
Article in English | MEDLINE | ID: mdl-24426306

ABSTRACT

Over the past decade, aquaculture has grown at an average annual growth rate of approximately 6 % worldwide despite many challenges. Viral diseases are one of the major challenges that are threatening a sustainable growth of finfish farming globally. Vaccination of farmed fish plays an important role in commercial fish farming to mitigate viral diseases. In this review, we summarized the major viral diseases that have caused serious economic losses, and emerging diseases that pose a potential threat to aquaculture. The current status of viral vaccines in farmed fish are discussed, particularly the different types of vaccines that were licensed in recent years and are now commercially available, and the routes of delivery of those vaccines including the merits and demerits of each of these delivery method. Furthermore, the article provides an overview of different experimental vaccines that have been reported in the literatures in recent years besides highlighting the future need for developing cost-effective, oral vaccines that can be easily applicable at farm level.

3.
Food Chem Toxicol ; 50(6): 1946-50, 2012 Jun.
Article in English | MEDLINE | ID: mdl-22497900

ABSTRACT

Severity of arsenic toxicity was reported to vary depending on its species. The present study reflects the status of different species of arsenic in goat following long-term exposure of arsenic leading to hepatic damage. The experiment was conducted with six black Bengal goats, which were administered with sodium arsenite orally at a dose rate of 2 mgkg(-1) daily for 84 days. Faeces, urine, hair and blood samples were collected from those animals at 14 days interval. Excretion of total arsenic was reduced from 56 days onwards through both faeces and urine indicating higher accumulation of arsenic in body. The speciation study revealed that urinary arsenic was mainly of organic type, whereas hair accumulated almost equal proportion of arsenite, arsenate and organo arsenicals. Goats excreted high proportion of organo arsenicals through faeces possibly due to hepatobiliary secretion of organo arsenic into the gut. Significantly elevated serum alanine aminotransferase and aspartate aminotransferase activities (p<0.05) along with histopathological changes in liver indicated hepatotoxicity. The arsenite fraction increased and organic proportion decreased in urine as the time progressed, which indicates that arsenite gets methylated in liver of goat. The study thus alluded that the toxicity of arsenic would aggravate if the animals were exposed for long time as the hepatotoxicity progressed resulting in decreased methylation and formation of organo arsenicals and decreased excretions through urine.


Subject(s)
Arsenic/toxicity , Administration, Oral , Alanine Transaminase/blood , Animals , Arsenates/chemistry , Arsenates/pharmacokinetics , Arsenates/toxicity , Arsenic/chemistry , Arsenic/pharmacokinetics , Arsenites/chemistry , Arsenites/pharmacokinetics , Arsenites/toxicity , Aspartate Aminotransferases/blood , Calibration , Fatty Liver/chemically induced , Fatty Liver/pathology , Female , Goats , Liver/pathology , Reproducibility of Results
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