Subject(s)
Dentist-Patient Relations , Peer Review, Health Care , Societies, Dental , Chicago , Humans , NegotiatingSubject(s)
Dental Health Services , Dentists , United States Indian Health Service , Humans , United States , WorkforceSubject(s)
Dentists/economics , Societies, Dental/economics , Training Support , Humans , Students, DentalABSTRACT
The goal of these experiments has been to capitalize on the functionally distinct responses of heteroclitic CTL to cross-reactive Ag to explore the role of Ag in regulating CTL proliferation and lytic function. The experiments here have examined one of these clones in detail but several such clones appear similar. The principal findings were: 1) proliferation and lysis may be optimally stimulated by quantitatively different interactions, 2) Ag can have negative as well as positive effects on the proliferative potential of the responding cell, and 3) both positive and negative effects on lysis can be mimicked by agents which are similar to the second messengers produced by stimulating the TCR.
Subject(s)
H-2 Antigens/immunology , T-Lymphocytes, Cytotoxic/immunology , Animals , Cell Division , Cytotoxicity, Immunologic , Interleukin-2/pharmacology , Mice , Mice, Inbred Strains , Models, Biological , Receptors, Antigen, T-Cell/drug effects , Receptors, Antigen, T-Cell/immunology , Recombinant Proteins/pharmacologyABSTRACT
A case is reported of neuroleptic-induced catatonia that developed after treatment with loxapine succinate, a drug not previously reported to cause catatonia. The syndrome, characterized by marked parkinsonism, episodes of posturing, social withdrawal, and urinary incontinence, persisted during haloperidol treatment and remitted when the drug was discontinued. This syndrome appears to represent severe neuroleptic-induced parkinsonism.
Subject(s)
Catatonia/chemically induced , Dibenzoxazepines/adverse effects , Loxapine/adverse effects , Parkinson Disease, Secondary/chemically induced , Adolescent , Catatonia/diagnosis , Diagnosis, Differential , Humans , Male , Parkinson Disease, Secondary/diagnosis , Psychotic Disorders/diagnosis , Psychotic Disorders/drug therapy , Schizophrenia, Catatonic/diagnosisSubject(s)
Amobarbital , Delirium/diagnosis , Interview, Psychological/methods , Psychotic Disorders/diagnosis , Female , Humans , Middle AgedABSTRACT
Anorexia nervosa, a complicated and serious illness, warrants the comprehensive use of several treatment modalities: behavior therapy, individual psychotherapy and family therapy. Singular use of and of these three have resulted in high mortality rates. The importance of legal commitment in dealing with this illness is also discussed.
