[The transplantation of embryonic nerve tissue in syringomyelia: initial clinical experience]. / Transplantatsiia émbrional'noi nervnoi tkani pri siringomielii: pervyi klinicheskii opyt.

The paper gives clinical findings of 5 cases of syringomyelia surgical treatment using neurotransplantation of embryonal spinal marrow nerve tissue into the intramedullary cavity. It also discusses problems of sampling, culture and transplantation of embryonal spinal marrow nerve tissues, as well as the results and prospects of this method application.

[The transport of colloidal gold-labelled albumin after its intra-abdominal administration in peritonitis]. / Transport mechennogo kolloidnym zolotom al'bumina posle intraabdominal'nogo vvedeniia pri peritonite.

We studied transportation of the colloidal gold labelled albumin 0.5-24 hours after intraabdominal administration of the tracer in normal rabbits and rabbits with experimental diffuse peritonitis (total 24 rabbits). Evacuation of foreign protein goes through the mesothelial stomata to the lymphatic vessels of diaphragm and further to the mediastinal lymph nodes. Sufficient amount of the tracer was captured by the phagocytes inside the lymph collectors. In case of peritonitis reticular cells of the lymph node displayed decreased capture of the tracer. This fact can be attributed to obstacles in the evacuation of the tracer from peritoneum and decreased phagocytic capacity of the reticular cells.

[The detection of albumin intraperitoneally administered to rabbits in the subclavian lymph node]. / Vyiavlenie intraperitoneal'no vvedennogo krolikam al'bumina v podkliuchichnom limfouzle.

With light and electron microscopy, the localization of human albumin labeled with colloidal gold is described in the subclavia lymph nodes of rabbits following an intraperitoneal injection of this labeled albumin. Most of the particles were found in the reticular cells of the sinus, and some particles were identified in the sinus macrophages. No particles were found inside lymph node follicules within 1 hour after injection. All stages of internalization of foreign protein inside lymph node cells were demonstrated.

[The morphological characteristics of globulin production during the vaccinal process induced by tularemia and brucellosis vaccines]. / Morfologicheskaia kharakteristika globulinproduktsii pri vaktsinal'nom protsesse, vyzvannom tuliaremiinoi i brutselleznoi vaktsinami.

Significant data on the dynamics of globulin production in guinea pigs in the process of immunogenesis after the injection of Francisella tularensis vaccine strain or conjugated brucellosis vaccine have been obtained by means of immunofluorescence and the enzyme immunoassay. The number of globulin-producing cells in lymphoid organs (the spleen, regional and remote lymph nodes) differs, depending on the injected antigen. The relationship between the character of immunomorphological changes in lymphoid organs and the dynamics of the increase of antibody titers in the peripheral blood of the animals after their immunization with conjugated brucellosis vaccine and the injection of avirulent F. tularensis has been established.

[Clinico-immunological and pathomorphological correlations in syringomyelia]. / Kliniko-immunologicheskie i patomorfologicheskie korreliatsii pri siringomielii.

The authors provide the results of studying humoral immunity of the blood serum, CSF and cystic fluid and pathomorphological alterations in the spinal membranes of 16 operated patients with communicating syringomyelia, which form the basis for viewing the immune mechanism as an important component of the pathogenesis of cyst formation. The indicators of humoral immunity mirror the activity of syringomyelia pathomorphosis and can be used for estimation of the time course of changes in the process and of the efficacy of the treatment given to the patients.

[Reactive-inflammatory and degenerative-dystrophic changes in the nervous system in experimental syringomyelia]. / O reaktivno-vospalitel'nykh i degenerativno-distroficheskikh izmeneniiakh v nervnoi sisteme pri ékperimental'noi siringomielii.

The results of immunomorphologic and histochemical investigations of 12 rabbits with experimental syringomyelia are presented. Chronic pachymeningitis of the hind brain, resulting from the administration of kaolin leads to the disorders of liquor circulation on the level of outlet of the fourth ventricle this being a start mechanism for the cavity formation in the spinal cord. The reactive inflammatory, degenerative and immune reactions accompany the formation of cavity in the nervous tissue. The formation of cavity is followed by asymmetrical segment demyelination and reparative hyperplasia of the astroglial cells and gliosis of the cavity walls.