ABSTRACT
The group of laypersons who founded St. Francis Hospital, Memphis, TN, in 1971 were dedicated to upholding Catholic values in health care yet often were questioned about the origins of their "Catholic" identity. "How can a hospital that is not owned by the diocese or sponsored by a religious institute call itself Catholic?" they were asked. The answer, St. Francis found, lies in the revised Code of Canon Law, which provides for a group of laypersons such as theirs to form a private association of the Christian faithful, be officially recognized by the Church, and receive canonical status. A participant in the pilot project through which CHA is studying the feasibility of alternative forms of sponsorship, St. Francis has worked closely with CHA in developing the private association's statutes and coordinating with the bishop provisions for evaluation of its stewardship. According to the statutes, the private association will monitor the hospital's adherence to Church values, and the bishop, serving in a pastoral capacity, will with CHA's assistance assess the association's effectiveness in carrying out its mission.
Subject(s)
Catholicism , Hospital Administration , Ownership , Hospital Bed Capacity, 500 and over , TennesseeABSTRACT
The antiviral drugs amantadine hydrochloride and rimantadine hydrochloride were tested as to their oncogenic potential using a serial line of Fischer rat embryo cells that previously had been shown to be an accurate indicator of chemicals known to be oncogenic in animal studies. Neither compound was found to have transforming activity. At slightly toxic levels, rimanbadine hydrochloride, but not amantadine hydrochloride, protected the same cell line from the transformation induced by the polycyclic hydrocarbons 3-methylcholanthrene and benzo(a)pyrene.
Subject(s)
Adamantane/pharmacology , Amantadine/pharmacology , Benzopyrenes , Bridged-Ring Compounds/pharmacology , Cell Transformation, Neoplastic/drug effects , Methylcholanthrene , Adamantane/analogs & derivatives , Animals , Cell Line , RatsABSTRACT
Three chlorinated hydrocarbons, proposed or already in use as industrial substitutes for the hydrocarbon trichloroethylene, were tested for in vitro transforming potential in a Fischer rat embryo cell system (F1706), which previously has been shown to be sensitive to transformation by chemical carcinogens. Trichloroethylene and the three substitutes (1, 1, 1 trichloroethane, tetrachloroethylene and methylene chloride) all were found to induce transformation, the three substitutes being equal or more efficient transforming agents.
