ABSTRACT
Mast cells (MCs) can release a variety of biologically active mediators under different circumstances, such as fever or vaccination. Our aim was to evaluate the incidence and severity of MC activation symptoms induced by SARS-CoV-2 virus (COVID-19) infection and vaccination in a cohort of 92 pediatric patients with cutaneous mastocytosis. Our findings support previous evidence on the safety of COVID-19 infection and vaccination in patients with MC disorders.
Subject(s)
COVID-19 Vaccines , COVID-19 , Mastocytosis, Cutaneous , SARS-CoV-2 , Adolescent , Child , Child, Preschool , Female , Humans , Infant , Male , COVID-19/prevention & control , COVID-19 Vaccines/adverse effects , Cross-Sectional Studies , Retrospective Studies , VaccinationSubject(s)
Biosimilar Pharmaceuticals , Hidradenitis Suppurativa , Mevalonate Kinase Deficiency , Psoriasis , Humans , Adalimumab/adverse effects , Ustekinumab/adverse effects , Hidradenitis Suppurativa/complications , Hidradenitis Suppurativa/drug therapy , Hidradenitis Suppurativa/chemically induced , Biosimilar Pharmaceuticals/adverse effects , Psoriasis/complications , Psoriasis/drug therapy , Psoriasis/chemically inducedABSTRACT
Idiopathic facial aseptic granuloma (IFAG) is characterized by the appearance of a painless reddish nodule in the facial region and is exclusive to children. It is usually located on the cheek. The resolution of these lesions is usually spontaneous in months and they heal without leaving a scar or with minimal scarring. Its etiology is unknown. The diagnosis is fundamentally clinical, although sometimes complementary tests such as ultrasound can be used. This pathology presents a chronic but benign clinical course with spontaneous resolution, so in these cases a wait-and-see approach is preferred (AU)
Idiopathic facial aseptic granuloma (IFAG) is characterized by the appearance of a painless reddish nodule in the facial region and is exclusive to children. It is usually located on the cheek. The resolution of these lesions is usually spontaneous in months and they heal without leaving a scar or with minimal scarring. Its etiology is unknown. The diagnosis is fundamentally clinical, although sometimes complementary tests such as ultrasound can be used. This pathology presents a chronic but benign clinical course with spontaneous resolution, so in these cases a wait-and-see attitude is preferred. (AU)
Subject(s)
Humans , Male , Child, Preschool , Granuloma/diagnostic imaging , Face , Remission, Spontaneous , UltrasonographyABSTRACT
Postpartum depression (PPD) affects 13% of mothers and can have a major impact on their lives and those of their children. However, most cases go undiagnosed, and the risk factors for this underdiagnosis are not yet fully known. We intended to analyze the influence of different sociodemographic and health factors associated with symptoms of postpartum depression. Data from the New York City Pregnancy Risk Assessment Monitoring System (PRAMS) for 2016-2017 were analyzed. 618 women met the inclusion criterion of recurring depressive symptoms. Most women who experienced PPD symptoms did not seek help. Seeking help was a much better predictor of the diagnosis of PPD when compared to questions regarding symptoms. The most important factors related to a decreased risk of not asking for help were having a previous mental health history and having doctor visits for a chronic illness. The racial group most at risk of not asking for help were Asian/Pacific Islander (API) women. Interventions aimed at reducing the stigma and increasing knowledge of PPD should be incorporated into the antenatal education of expectant mothers, particularly among women who may not have previously sought care for mental or chronic illnesses.
