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1.
Cureus ; 13(11): e19715, 2021 Nov.
Article in English | MEDLINE | ID: mdl-34900496

ABSTRACT

Flexor sheath infections (FSIs) are soft tissue infections affecting the hand, which, if mismanaged, can have devastating consequences. Clinical assessment is key to diagnosis, with many relying on Kanavel cardinal signs as an aid. To prevent unnecessary operative intervention and the associated post-operative combined patient and healthcare burden, it is key that patients with FSIs are correctly identified. It would also be useful to stratify severity of FSIs without surgical exploration. To date, there is no accepted method to assist clinicians in doing so. We retrospectively analysed data from a five-year period to see if we could identify pre-operatively (a) accurate predictors of FSIs and (b) severity of the FSIs. We established that only the presence of all four Kanavel cardinal signs significantly predicted the presence of an FSI. No other variable that was available prior to surgery could predict either presence or severity of infection.

2.
Cureus ; 13(12): e20425, 2021 Dec.
Article in English | MEDLINE | ID: mdl-34956799

ABSTRACT

High-pressure injection injuries of the hand are uncommon but are associated with significant morbidity and require urgent surgical intervention. We describe a case of high-pressure injection of cement into the digit of a male patient while using an airless spray gun. We outline the initial assessment and surgical intervention, patient counselling regarding definitive management, and long-term outcomes of his injury. We also discuss mechanisms of high-pressure injection injuries, reconstructive options, and present a review of outcomes in patients sustaining similar injuries.

3.
Br J Hosp Med (Lond) ; 80(9): 492-493, 2019 Sep 02.
Article in English | MEDLINE | ID: mdl-31498662
5.
J Cutan Pathol ; 43(1): 53-6, 2016 Jan.
Article in English | MEDLINE | ID: mdl-26010041

ABSTRACT

A 19-year-old male with a port wine stain on the base of his neck presented with a 5-month history of gradual thickening of the involved skin which interfered with clothing and caused repeated bleeding. The lesion was excised and histopathologic examination revealed angiolymphoid hyperplasia with eosinophilia (ALHE) arising from the pre-existing port wine stain - a rare finding with only one previously reported case. Additionally the lesion was associated with elevated serum renin levels which virtually normalized following excision of the lesion. We further demonstrated the expression of angiotensin converting enzyme and angiotensin II receptors 1 and 2 by the lesion and discuss the possible role of the renin-angiotensin system in this condition.


Subject(s)
Angiolymphoid Hyperplasia with Eosinophilia/diagnosis , Port-Wine Stain/diagnosis , Port-Wine Stain/pathology , Angiolymphoid Hyperplasia with Eosinophilia/metabolism , Angiolymphoid Hyperplasia with Eosinophilia/surgery , Humans , Male , Neck/pathology , Peptidyl-Dipeptidase A/biosynthesis , Port-Wine Stain/metabolism , Port-Wine Stain/surgery , Receptor, Angiotensin, Type 1/biosynthesis , Receptor, Angiotensin, Type 2/biosynthesis , Renin/blood , Young Adult
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