ABSTRACT
El presente trabajo examina el impacto del tratamiento intensivo en un Hospital de Día de Salud Mental (HD-SM) sobre el uso posterior de recursos asistenciales (comunitarios y hospitalarios), así como ocupacionales y formativos. Se parte de un diseño descriptivo longitudinal y ambispectivo en el que se estudia de forma innovadora el uso diferencial de los recursos por parte de los usuarios de la red de Salud Mental, antes y después del tratamiento en HD. Finalmente, se discuten las implicaciones y recomendaciones clínicas de acuerdo con los resultados. (AU)
This work examines the impact of intensive treatment in a Mental Health Day Hospital (HD) on the subsequent use of healthcare resources (community and hospital), as well as occupational and training ones. It starts from a longitudinal and ambispective descriptive design in which the differential use of resources by users of the Mental Health network is studied in an innovative way, before and after treatment in HD. Finally, the clinical implications and recommendations are discussed according to the results. (AU)
Subject(s)
Humans , Male , Female , Young Adult , Adult , Middle Aged , Day Care, Medical , Mental Health , Health Resources , Spain , Epidemiology, Descriptive , Longitudinal StudiesABSTRACT
AIM: To evaluate the impact of long-acting injectable antipsychotics (LAIs) on the risk of hospitalization and the length of hospitalization in the setting of an early intervention program for patients with recent-onset psychosis. METHODS: Observational, retrospective study conducted under routine clinical practice conditions. We included all patients admitted from July 2015 to April 2020 to the Early Intervention Program in Psychosis. We analysed the incidence of hospitalization and hospitalization days before and after treatment with LAIs and calculated the incidence rate ratio (IRR). We also compared the outcomes of patients treated with LAIs with those of the patients maintained on oral antipsychotics using a binomial negative regression analysis. RESULTS: A total of 170 patients were included in the program. Of them, 34 (20%) received LAIs (aripiprazole [n = 22], and paliperidone/risperidone [n = 12]). There was an 89% reduction in the incidence of hospitalizations after treatment with LAIs (IRR 0.11, 95%CI 0.05-0.21; p < .0001). The IRR for LAIs vs. oral antipsychotics was 0.87 (95%CI, 0.24-3.18; p = .829). The presence of a substance use disorder significantly increased the rate of hospitalizations by 123% (IRR 2.23, 95%CI 1.31-3.78). Analyses of hospitalization days showed similar results. CONCLUSIONS: Our results suggest that LAIs are useful for the management of patients with recent-onset psychosis who fail treatment with oral antipsychotics. Whether LAIs are superior to oral antipsychotics as first-line treatment of patients with early psychosis and/or could play a special role in managing patients with early psychosis and comorbid substance use disorders should be further evaluated.
