ABSTRACT
INTRODUCTION: Recently, case reports have shown that immature teeth diagnosed with necrotic pulp and periapical periodontitis can be repaired through a regenerative endodontic procedure. True regeneration depends on the presence of stem cells in the remaining vital tissues. The aim of this study was to evaluate the histologic condition of the pulp tissue, root apical papilla, and periapical tissues after inducing endodontic infection in immature rat teeth for different periods. METHODS: This study evaluated 18 first upper rat molars (36 roots). Periapical lesions were induced and were confirmed radiographically, and the animals were divided into 3 groups according to the days of pulp exposure for endodontic infection induction: 30, 60, and 90 days. Histologic analysis was performed in 5 different areas (ie, cervical, middle, and apical root canal thirds; the apical papilla; and the periapex surrounding the apical papilla). RESULTS: At 30 days, one third of the specimens still showed vital but intensely inflamed pulp tissue in the apical third and vital apical papilla with varying degrees of inflammation. After 60 days, the results were similar with respect to the apical pulp tissue and apical papilla. Completely necrotic pulp tissue in the space canal and vital apical papilla were observed in about 67% of the cases after 90 days. CONCLUSIONS: Vital pulp tissue was observed in the apical third until 60 days and in the vital apical papilla until 90 days of infection in a rat model.
Subject(s)
Dental Pulp Cavity/pathology , Dental Pulp Diseases/pathology , Dental Pulp/pathology , Molar/pathology , Periapical Tissue/pathology , Tooth Apex/pathology , Animals , Dental Pulp Exposure/pathology , Dental Pulp Necrosis/pathology , Leukocytes, Mononuclear/pathology , Male , Neutrophils/pathology , Periapical Diseases/pathology , Pulpitis/pathology , Radiography, Bitewing , Rats , Rats, Wistar , Time FactorsABSTRACT
Los hospitales se constituyen en una importante puerta de ingreso para el sistema de salud. El objetivo de esta investigación cuali-cuantitativa, fue observar la representación social de los pacientes de la Facultad de Odontología de Araçatuba (FOA) - UNESP, que se benefician de la interacción: universidad pública y hospitales generales. Fueron escuchados por medio de entrevistas abiertas, grabadas y transcritas, con todos los pacientes (105) que frecuentaran las antesalas de la Clínica Integrada, en el primer semestre de 2005, con la pregunta: ¿Como supiste de la atención aquí en la FOA? Fue construido el Discurso del Sujeto Colectivo (DSC), la representación de campo que permite una sociedad decir como se fuera un solo individuo. Veinte y tres de los pacientes, fueron encaminados a la FOA, por UBS de Araçatuba(7) y región(16) y 21 pacientes por hospitales. Se ha podido constatar que la interacción universidad pública y hospitales generales es una realidad.
Hospitals are very important for the health system. The objective of this quali-quantitative research was to visualize patients social representation, which profited of the interaction between public universities and hospitals. 105 patients in the waiting rooms at the Integrated Clinic at FOA - UNESP in the first semester 2005 answered to the question: "How did you know about the service at FOA? " - in opened interviews, recorded or written. A collective speech of the subject represented the field that allouds a society to speak as one. Twenty three of all patients have been sent to FOA by Health Assistance Centers in Araçatuba (7) and region (16) and twenty one patients assisted in Araçatuba by emergency. We can observe that the interaction between the public universities and general hospitals is a reality.
