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1.
Braz J Microbiol ; 50(1): 297-305, 2019 Jan.
Article in English | MEDLINE | ID: mdl-30637645

ABSTRACT

Helicobacter infection has been associated with hepatobiliary diseases in humans and animals. The aims of this study were to identify Helicobacter species in the hepatobiliary tract of dogs and to elucidate the possible association of these bacteria in liver diseases. Twenty-seven gastric and hepatobiliary samples were collected from 33 dogs with hepatic lesions and 17 dogs with no liver histological changes. Warthin-Starry staining, immunohistochemical assay, and PCR were performed to detect the presence of Helicobacter. Helicobacter genus was detected in 21.2% of the samples with hepatic lesions. The main lesion was chronic hepatitis. Immunohistochemistry revealed infection in liver (1/5) and gallbladder (1/3) 32 samples. The sequence analysis of seven amplicons of the 16S rRNA gene of Helicobacter genus from hepatobiliary samples showed 97.8 to 100% of nucleotide identity with gastric helicobacter. One amplicon of the ureA and ureB gene of Helicobacter genus from the stomach showed 89.1 to 90.7% nucleotide identity with H. heilmannii. The presence of Helicobacter genus in liver samples showing hepatic lesions suggests the involvement of these bacteria in the etiology of hepatobiliary disease in dogs. DNA sequences were similar to gastric Helicobacter species, reinforcing the hypothesis of bacterial translocation from the stomach to liver by the biliary pathway.


Subject(s)
Dog Diseases/microbiology , Gallbladder/microbiology , Helicobacter Infections/veterinary , Helicobacter/isolation & purification , Liver/microbiology , Stomach/microbiology , Animals , Bacterial Proteins/genetics , Bacterial Proteins/metabolism , Dog Diseases/pathology , Dogs , Gallbladder/pathology , Helicobacter/classification , Helicobacter/genetics , Helicobacter/physiology , Helicobacter Infections/microbiology , Helicobacter Infections/pathology , Liver/pathology , Stomach/pathology
2.
Ars vet ; 27(4): 226-230, 2011.
Article in Portuguese | VETINDEX | ID: vti-764871

ABSTRACT

Mucopolissacaridoses são um grupo de afecções hereditárias do armazenamento lisossomal , causada por deficiência de hidrolases lisossomais, necessárias para a degradação das glicosaminoglicanas. Neste relato são escritos dois casos de mucopolissacaridose em cães: Um cão macho, Pitbull, de 60 dias, foi atendido devido à dificuldade de locomoção com os quatro membros e aumento de volume articular. No exame clínico constatou-se aumento de volume e deformidades em articulações e pectus cavinatum. Nas radiografias do sistema esquelético observou-se disostose multiplex. O outro paciente, uma canina fêmea, Rottweiler, de oito meses, foi atendida devido à dificuldade progressiva de locomoção. No exame clínico constatou-se tetraplegia, opacidade corneal, aumento de volume em língua e deformidade em crânio. Para triagem de mucopolissacaridose, realizou-se na urina dosagem qualitativa e quantitativa de glicosaminoglicanos e ensaios enzimáticos no plasma para dosar a atividade de enzimas lisossômicas. Apesar da confirmação de mucopolissacaridose com os testes de triagem, n&ati

3.
Arq. bras. med. vet. zootec ; Arq. bras. med. vet. zootec. (Online);59(6)dez. 2007.
Article in Portuguese | LILACS-Express | LILACS, VETINDEX | ID: biblio-1462583

ABSTRACT

Clinical results after decompressive surgery were evaluated in 45 dogs with cervical or thoracolumbar intervertebral disk disease. After surgery, 35 dogs recovered totally, eight (17.8%) partially, and two (4.4%) did not present any change in clinical findings. Eight dogs with paraplegy and loss of deep pain perception showed improvement, with total recovering in 62.5% of cases. Surgery was effective in four dogs with tetraparesy. Decompressive surgery (cervical slot or hemilaminectomy), with removal of disk material from inside the vertebral canal, was an effective form to produce functional improvement in dogs with this disease.


Avaliaram-se os resultados clínicos após realização de cirurgia descompressiva em 45 cães com doença do disco intervertebral cervical ou toracolombar. Após a cirurgia, 35 cães (77,8%) recuperaram-se totalmente, oito (17,8%) parcialmente e dois (4,4%) não apresentaram alteração do quadro inicial. Em oito cães com paraplegia e perda da sensibilidade dolorosa profunda houve completa melhora do quadro clínico, com recuperação total em 62,5% dos casos. Em quatro cães com tetraparesia, a cirurgia foi eficaz. A cirurgia descompressiva (slot cervical e hemilaminectomia toracolombar), com a retirada do material do disco do interior do canal vertebral, foi uma forma efetiva de gerar melhora do quadro funcional.

4.
Arq. bras. med. vet. zootec ; 59(6): 1445-1450, dez. 2007. tab
Article in Portuguese | VETINDEX | ID: vti-7063

ABSTRACT

Avaliaram-se os resultados clínicos após realização de cirurgia descompressiva em 45 cães com doença do disco intervertebral cervical ou toracolombar. Após a cirurgia, 35 cães (77,8 por cento) recuperaram-se totalmente, oito (17,8 por cento) parcialmente e dois (4,4 por cento) não apresentaram alteração do quadro inicial. Em oito cães com paraplegia e perda da sensibilidade dolorosa profunda houve completa melhora do quadro clínico, com recuperação total em 62,5 por cento dos casos. Em quatro cães com tetraparesia, a cirurgia foi eficaz. A cirurgia descompressiva (slot cervical e hemilaminectomia toracolombar), com a retirada do material do disco do interior do canal vertebral, foi uma forma efetiva de gerar melhora do quadro funcional(AU)


Clinical results after decompressive surgery were evaluated in 45 dogs with cervical or thoracolumbar intervertebral disk disease. After surgery, 35 dogs recovered totally, eight (17.8 percent) partially, and two (4.4 percent) did not present any change in clinical findings. Eight dogs with paraplegy and loss of deep pain perception showed improvement, with total recovering in 62.5 percent of cases. Surgery was effective in four dogs with tetraparesy. Decompressive surgery (cervical slot or hemilaminectomy), with removal of disk material from inside the vertebral canal, was an effective form to produce functional improvement in dogs with this disease(AU)


Subject(s)
Animals , Dogs , Decompression, Surgical/rehabilitation , Decompression, Surgical/veterinary , Spine/pathology
5.
Arq. bras. med. vet. zootec ; Arq. bras. med. vet. zootec. (Online);59(6): 1445-1450, dez. 2007. tab
Article in Portuguese | LILACS | ID: lil-476115

ABSTRACT

Avaliaram-se os resultados clínicos após realização de cirurgia descompressiva em 45 cães com doença do disco intervertebral cervical ou toracolombar. Após a cirurgia, 35 cães (77,8 por cento) recuperaram-se totalmente, oito (17,8 por cento) parcialmente e dois (4,4 por cento) não apresentaram alteração do quadro inicial. Em oito cães com paraplegia e perda da sensibilidade dolorosa profunda houve completa melhora do quadro clínico, com recuperação total em 62,5 por cento dos casos. Em quatro cães com tetraparesia, a cirurgia foi eficaz. A cirurgia descompressiva (slot cervical e hemilaminectomia toracolombar), com a retirada do material do disco do interior do canal vertebral, foi uma forma efetiva de gerar melhora do quadro funcional


Clinical results after decompressive surgery were evaluated in 45 dogs with cervical or thoracolumbar intervertebral disk disease. After surgery, 35 dogs recovered totally, eight (17.8 percent) partially, and two (4.4 percent) did not present any change in clinical findings. Eight dogs with paraplegy and loss of deep pain perception showed improvement, with total recovering in 62.5 percent of cases. Surgery was effective in four dogs with tetraparesy. Decompressive surgery (cervical slot or hemilaminectomy), with removal of disk material from inside the vertebral canal, was an effective form to produce functional improvement in dogs with this disease


Subject(s)
Animals , Dogs , Spine/pathology , Decompression, Surgical/rehabilitation , Decompression, Surgical/veterinary
6.
Article in Portuguese | VETINDEX | ID: vti-447868

ABSTRACT

Clinical results after decompressive surgery were evaluated in 45 dogs with cervical or thoracolumbar intervertebral disk disease. After surgery, 35 dogs recovered totally, eight (17.8%) partially, and two (4.4%) did not present any change in clinical findings. Eight dogs with paraplegy and loss of deep pain perception showed improvement, with total recovering in 62.5% of cases. Surgery was effective in four dogs with tetraparesy. Decompressive surgery (cervical slot or hemilaminectomy), with removal of disk material from inside the vertebral canal, was an effective form to produce functional improvement in dogs with this disease.


Avaliaram-se os resultados clínicos após realização de cirurgia descompressiva em 45 cães com doença do disco intervertebral cervical ou toracolombar. Após a cirurgia, 35 cães (77,8%) recuperaram-se totalmente, oito (17,8%) parcialmente e dois (4,4%) não apresentaram alteração do quadro inicial. Em oito cães com paraplegia e perda da sensibilidade dolorosa profunda houve completa melhora do quadro clínico, com recuperação total em 62,5% dos casos. Em quatro cães com tetraparesia, a cirurgia foi eficaz. A cirurgia descompressiva (slot cervical e hemilaminectomia toracolombar), com a retirada do material do disco do interior do canal vertebral, foi uma forma efetiva de gerar melhora do quadro funcional.

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