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Pathol Biol (Paris) ; 27(9): 571-8, 1979 Nov.
Article in French | MEDLINE | ID: mdl-44741

ABSTRACT

For a period of 17 months, 670 pneumococci, mostly isolated in the Paris area, have been typed with contercurrent-immunoelectrophoresis ; 338 of them come from cases of pneumonia, bacteremia, meningitis and acute otitis media. An important regrouping of the most frequent serotypes among the 83 known serotypes makes possible a vaccinal prophylaxis. The tetradecavalent vaccine which is now for sale in USA gives, in the four main pathologies of this enquiry, a coverage superior to 80 percent. Choosing the 14 most frequent serotypes of the four main pathologies of their data the authors propose the following vaccinal formula : 1, 3, 4, 5, 6, 7, 8, 10, 12, 14, 15, 18, 19, 23.


Subject(s)
Streptococcus pneumoniae/classification , Adolescent , Adult , Aged , Bacterial Vaccines , Child , Child, Preschool , Counterimmunoelectrophoresis , France , Humans , Immunotherapy , Infant , Infant, Newborn , Meningitis, Pneumococcal/microbiology , Middle Aged , Otitis Media/microbiology , Pneumonia/microbiology , Polysaccharides, Bacterial , Sepsis/microbiology , Serotyping , Streptococcus pneumoniae/immunology
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