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1.
Highlight report: cytoprotective signaling in toxicology.
Bolt, H M; Marchan, R.
Arch Toxicol ; 89(11): 2189-91, 2015 Nov.
Article in English | MEDLINE | ID: mdl-26525396

Subject(s)
Cytoprotection/physiology , Signal Transduction/drug effects , Toxicology , Humans , Stress, Physiological/drug effects
2.
Standard compounds for establishment of in vitro test systems.
Hengstler, J G; Marchan, R; Bolt, H M.
Arch Toxicol ; 88(12): 2083-4, 2014 Dec.
Article in English | MEDLINE | ID: mdl-25354799

Subject(s)
Animal Testing Alternatives/standards , In Vitro Techniques/standards , Liver/drug effects , Toxicology/standards , Animals , Humans
3.
Research on plant extracts and phytochemicals: criteria for evaluation.
Hammad, S; Marchan, R; Bolt, H M.
Arch Toxicol ; 88(1): 11-3, 2014 Jan.
Article in English | MEDLINE | ID: mdl-24185950

Subject(s)
Biomedical Research/methods , Phytochemicals/pharmacology , Plant Extracts/pharmacology , Biomedical Research/standards , Drug Discovery/methods
4.
Recent developments in in vitro toxicology: perspectives of European research and Tox21.
Marchan, R; van Thriel, C; Bolt, H M.
Arch Toxicol ; 87(12): 2043-6, 2013 Dec.
Article in English | MEDLINE | ID: mdl-24221536

Subject(s)
Animal Testing Alternatives/trends , Toxicity Tests/trends , Toxicology/trends , Animals , High-Throughput Screening Assays , Humans , In Vitro Techniques , United States , Xenobiotics/metabolism , Xenobiotics/toxicity
5.
The cytoprotective and the dark side of Nrf2.
Marchan, R; Bolt, H M.
Arch Toxicol ; 87(12): 2047-50, 2013 Dec.
Article in English | MEDLINE | ID: mdl-24232176

Subject(s)
Carcinogens/metabolism , Cytoprotection , NF-E2-Related Factor 2/physiology , Carcinogens/antagonists & inhibitors , Humans , NF-E2-Related Factor 2/genetics , NF-E2-Related Factor 2/metabolism
6.
The nanotoxicology revolution.
Gebel, T; Marchan, R; Hengstler, J G.
Arch Toxicol ; 87(12): 2057-62, 2013 Dec.
Article in English | MEDLINE | ID: mdl-24202081

Subject(s)
Nanostructures/toxicity , Nanotechnology/trends , Animals , Cytokines/metabolism , Humans , Immunity, Cellular/drug effects , Oxidative Stress/drug effects , Pharmacokinetics , Risk Assessment
7.
Recent developments in nanotoxicology.
Bolt, H M; Marchan, R; Hengstler, J G.
Arch Toxicol ; 87(6): 927-8, 2013 Jun.
Article in English | MEDLINE | ID: mdl-22526375

Subject(s)
Nanostructures/adverse effects , Nanotechnology/trends , Toxicology/trends , Animals , Humans , Risk Assessment , Toxicity Tests
8.
Role of heat shock proteins in stress response and carcinogenesis.
Cadenas, C; Marchan, R; Bolt, H M.
Arch Toxicol ; 87(1): 1-2, 2013 Jan.
Article in English | MEDLINE | ID: mdl-23184253

Subject(s)
DNA-Binding Proteins/genetics , Heat-Shock Proteins/physiology , Neoplasms/genetics , Neoplasms/pathology , Transcription Factors/genetics , Heat Shock Transcription Factors , Humans
9.
Buckyballs (fullerenes): free radical sponges or inflammatory agents?
Cadenas, C; Marchan, R; Hengstler, J G.
Arch Toxicol ; 86(12): 1807-8, 2012 Dec.
Article in English | MEDLINE | ID: mdl-23128830

Subject(s)
Cell Survival/drug effects , Fullerenes/toxicity , Mutagens , Oxidative Stress/drug effects , Animals , Humans
10.
Polymorphisms hit the headlines.
Stewart, J D; Marchan, R.
Arch Toxicol ; 86(12): 1799-801, 2012 Dec.
Article in English | MEDLINE | ID: mdl-23135550

Subject(s)
Polymorphism, Genetic/genetics , Genome-Wide Association Study , Humans , Polymorphism, Single Nucleotide/genetics , Urinary Bladder Neoplasms/chemically induced , Xenobiotics/metabolism
11.
The human bitumen study hits the headlines.
Van Thriel, C; Marchan, R.
Arch Toxicol ; 86(12): 1803-5, 2012 Dec.
Article in English | MEDLINE | ID: mdl-23108913

Subject(s)
Carcinogens/toxicity , Hydrocarbons/toxicity , Air Pollutants, Occupational , Animals , DNA Damage , Humans , Inflammation/chemically induced , Inflammation/pathology , Occupational Exposure , Respiratory Tract Diseases/chemically induced , Respiratory Tract Diseases/pathology
12.
Nanotoxicology and oxidative stress control: cutting-edge topics in toxicology.
Bolt, H M; Marchan, R; Hengstler, J G.
Arch Toxicol ; 86(11): 1629-35, 2012 Nov.
Article in English | MEDLINE | ID: mdl-23052200

Subject(s)
Nanostructures/toxicity , Nanotechnology , Oxidative Stress , Toxicology/trends , Periodicals as Topic
13.
Polymorphisms hit the headlines.
Stewart, J D; Marchan, R.
Arch Toxicol ; 86(11): 1637-9, 2012 Nov.
Article in English | MEDLINE | ID: mdl-22990137

Subject(s)
Polymorphism, Single Nucleotide , Urinary Bladder Neoplasms/genetics , Animals , Humans
14.
Systems biology meets toxicology.
Marchan, R; Bolt, H M; Hengstler, J G.
Arch Toxicol ; 86(8): 1157-8, 2012 Aug.
Article in English | MEDLINE | ID: mdl-22776964

Subject(s)
Liver/drug effects , Systems Biology , Toxicology/methods , Animals , Humans
15.
Progress in gene expression profiling by the introduction of metagenes.
Marchan, R; Bolt, H M.
Arch Toxicol ; 86(8): 1165-6, 2012 Aug.
Article in English | MEDLINE | ID: mdl-22684802

Subject(s)
Gene Expression Profiling/methods , Metagenome/drug effects , Metagenomics , Toxicogenetics/methods , Animals , Gene Expression Regulation/drug effects , Humans , Risk Assessment , Risk Factors
16.
Zinc as a multipurpose trace element.
Marchan, R; Cadenas, C; Bolt, H M.
Arch Toxicol ; 86(4): 519-20, 2012 Apr.
Article in English | MEDLINE | ID: mdl-22415766

Subject(s)
Deficiency Diseases/metabolism , Dietary Supplements , Trace Elements/deficiency , Trace Elements/metabolism , Zinc/deficiency , Zinc/metabolism , Humans
17.
Imatinib: the controversial discussion on cardiotoxicity induced by endoplasmic reticulum (ER) stress.
Marchan, R; Bolt, H M.
Arch Toxicol ; 86(3): 339-40, 2012 Mar.
Article in English | MEDLINE | ID: mdl-22327847

Subject(s)
Antineoplastic Agents/adverse effects , Endoplasmic Reticulum Stress/drug effects , Heart/drug effects , Piperazines/adverse effects , Pyrimidines/adverse effects , Benzamides , Humans , Imatinib Mesylate
18.
Pyrethroid insecticide neurotoxicity.
van Thriel, C; Hengstler, J G; Marchan, R.
Arch Toxicol ; 86(3): 341-2, 2012 Mar.
Article in English | MEDLINE | ID: mdl-22331241

Subject(s)
Insecticides/toxicity , Neurotoxicity Syndromes/etiology , Pyrethrins/toxicity , Animals , Humans
19.
A special issue on nanotoxicology.
Marchan, R.
EXCLI J ; 11: 176-7, 2012.
Article in English | MEDLINE | ID: mdl-27231465
20.
Key messages from Experimental and Clinical Sciences.
Marchan, R.
EXCLI J ; 11: 688-91, 2012.
Article in English | MEDLINE | ID: mdl-27231471
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