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Successful treatment with rituximab of one patient with CANOMAD neuropathy.
Delmont, Emilien; Jeandel, P Y; Hubert, A M; Marcq, L; Boucraut, J; Desnuelle, C.
J Neurol ; 257(4): 655-7, 2010 Apr.
Article in English | MEDLINE | ID: mdl-19960199

ABSTRACT

We report a successful treatment with rituximab in a patient with CANOMAD neuropathy resistant to previous therapy. The titers of anti-disialosyl antibodies were decreased 3 months after the beginning of the treatment and the sensory ataxia clearly improved after 9 months of therapy.


Subject(s)
Anemia, Hemolytic, Autoimmune/drug therapy , Antibodies, Monoclonal/therapeutic use , Immunologic Factors/therapeutic use , Ophthalmoplegia/drug therapy , Polyradiculoneuropathy/drug therapy , Aged , Anemia, Hemolytic, Autoimmune/complications , Antibodies, Monoclonal, Murine-Derived , Antigens, Surface/immunology , Female , Humans , Immunoglobulin M/blood , Oligosaccharides/immunology , Ophthalmoplegia/complications , Polyradiculoneuropathy/complications , Rituximab
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