ABSTRACT
MR-tomography (MRT) was used to investigate 10 isolated hearts from patients who died of various cardiovascular diseases. The purpose was to study the accuracy of MRT for determination of the myocardial mass (MM) of the left and right ventricles. MM was calculated using Simpson's method and the "area-length" formula. The first method demonstrated a high correlation of MRT results with autopsy findings with relation to the left, right ventricles and the interventricular septum (r = 0.98, 0.88, 0.85, respectively). The accuracy of the second method was also very high (r = 0.96 with relation to the left ventricle), however great scattering of MM values with relation to true values was noted. MRT can serve as a highly informative method in the evaluation of the ventricular MM and the time course of its changes.
Subject(s)
Magnetic Resonance Imaging/methods , Myocardium/pathology , Adult , Aged , Cardiovascular Diseases/diagnosis , Cardiovascular Diseases/pathology , Female , Heart Ventricles/pathology , Humans , In Vitro Techniques , Male , Middle Aged , Organ SizeABSTRACT
Magnetic resonance tomography was performed to examine the kidneys, brain, adrenals, vessels, and heart in 110 patients with malignant arterial hypertension (MAH). The findings were compared with those of the examination of healthy subjects and patients with benign hypertensive disease (BHD). As compared to the controls, all the MAH patients had changes in the target organs, however, their nature and magnitude varied with under underlying MAH disease. Renal alterations were most profound in chronic glomerulonephritis. All the patients displayed signs of concentrated cardiac hypertrophy: its maximum degree being noted in renovascular hypertension, the least, in MAH of adrenal genesis. Examination of the central nervous system in MAH patients revealed that the ventricular system and subdural space were dilated. It was shown that it was feasible to diagnose hypertrophic encephalopathy in the prehospital period by employing magnetic resonance tomography.
Subject(s)
Hypertension, Malignant/diagnosis , Magnetic Resonance Imaging , Adolescent , Adrenal Glands/pathology , Adult , Brain/pathology , Cardiomegaly/diagnosis , Diagnosis, Differential , Humans , Hypertension/diagnosis , Hypertension, Malignant/pathology , Hypertension, Renovascular/diagnosis , Kidney/pathology , Middle Aged , Myocardium/pathologyABSTRACT
To study the value of magnetic resonance imaging (MRI) in the determination of heart morphology and function, 47 patients with malignant arterial hypertension (MAH) were examined. The images of the both ventricles, ventricular septum (VS), left ventricular (LV) apex and posterior wall (LVPW), aortic root and left atrium were studied. In all the patients, symmetric LV hypertrophy was found and the thickness of LVPW was 1.46 cm, IVS, 1.53 cm. The heart chambers were not enlarged. The diameter of aortic root was 3.36 cm. There was a close correlation between LV hypertrophy and blood pressure. We conclude that the development of LV hypertrophy in MAH is not merely a compensatory process response to high blood pressure.
Subject(s)
Heart/physiopathology , Hypertension, Malignant/diagnosis , Magnetic Resonance Imaging/methods , Adolescent , Adult , Cardiomegaly/diagnosis , Cardiomegaly/physiopathology , Electrocardiography , Female , Fundus Oculi , Hemodynamics/physiology , Humans , Hypertension, Malignant/physiopathology , Magnetic Resonance Imaging/instrumentation , Male , Middle AgedABSTRACT
MR-tomography (MRT) was performed in 10 patients with primary pulmonary hypertension (PPH) and in 20 healthy volunteers. The investigation was performed by means of a MR-tomograph with a resistive magnet. ECG-triggering and multislice-multiecho method were used. MRT gave high quality images of the right heart in various phases of the cardiac cycle. The most characteristic symptoms of PPH exhibited by MRT were: forward rotation of the right ventricle (RV), pronounced dilation of the right heart, right ventricular myocardial hypertrophy, relative and absolute diminishing of the left ventricle size, paradoxical motion of the interventricular septum and alterations in its shape. 50% of the examined patients had highly intensive blood flow signal in the pulmonary artery lumen.
