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Rev Inst Med Trop Sao Paulo ; 57(4): 359-60, 2015.
Article in English | MEDLINE | ID: mdl-26422164

ABSTRACT

In this brief communication we describe the occurrence of a KPC-producing Serratia marcescens isolate in a home-care patient from Recife, Brazil. The blaKPC, blaSPM, blaIMP, blaVIM, blaOXA, blaCTX-M, blaSHV, blaTEM and blaGES genes were investigated by Polymerase Chain Reaction (PCR) and DNA sequencing. The isolate was positive for blaKPC-2 and blaTEM-1 and was resistant to aztreonam, cefepime, cefotaxime, imipenem, meropenem, gentamicin, ciprofloxacin and cefazidime, and susceptible only to amikacin, tigecycline and gatifloxacin. This is the first report in Brazil of KPC-producing S. marcescens clinical isolate outside of a hospital environment. Caregivers should be alert for the presence of this isolate in the community setting.


Subject(s)
Anti-Bacterial Agents/pharmacology , Serratia Infections/microbiology , Serratia marcescens/drug effects , Serratia marcescens/isolation & purification , beta-Lactamases/biosynthesis , Brazil , Electrophoresis, Gel, Pulsed-Field , Home Care Services , Humans , Male , Microbial Sensitivity Tests , Middle Aged , Serratia marcescens/enzymology
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