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1.
PLoS One ; 9(2): e83727, 2014.
Article in English | MEDLINE | ID: mdl-24551031

ABSTRACT

MicroRNAs, or miRNAs, are endogenously encoded small RNAs that play a key role in diverse plant biological processes. Jatropha curcas L. has received significant attention as a potential oilseed crop for the production of renewable oil. Here, a sRNA library of mature seeds and three mRNA libraries from three different seed development stages were generated by deep sequencing to identify and characterize the miRNAs and pre-miRNAs of J. curcas. Computational analysis was used for the identification of 180 conserved miRNAs and 41 precursors (pre-miRNAs) as well as 16 novel pre-miRNAs. The predicted miRNA target genes are involved in a broad range of physiological functions, including cellular structure, nuclear function, translation, transport, hormone synthesis, defense, and lipid metabolism. Some pre-miRNA and miRNA targets vary in abundance between the three stages of seed development. A search for sequences that produce siRNA was performed, and the results indicated that J. curcas siRNAs play a role in nuclear functions, transport, catalytic processes and disease resistance. This study presents the first large scale identification of J. curcas miRNAs and their targets in mature seeds based on deep sequencing, and it contributes to a functional understanding of these miRNAs.


Subject(s)
Gene Expression Regulation, Plant , Jatropha/genetics , MicroRNAs/genetics , RNA, Messenger/genetics , RNA, Plant/genetics , Seeds/genetics , Gene Expression Regulation, Developmental , Gene Library , High-Throughput Nucleotide Sequencing , Jatropha/growth & development , Jatropha/metabolism , Metabolic Networks and Pathways , MicroRNAs/metabolism , Molecular Sequence Annotation , RNA, Messenger/metabolism , Seeds/growth & development , Seeds/metabolism
2.
Funct Integr Genomics ; 13(3): 323-38, 2013 Aug.
Article in English | MEDLINE | ID: mdl-23757006

ABSTRACT

The Lesion Simulating Disease (LSD) genes encode a family of zinc finger proteins that are reported to play an important role in the hypersensitive response and programmed cell death (PCD) that are caused by biotic and abiotic stresses. In the present study, 117 putative LSD family members were identified in Viridiplantae. Genes with one, two, or three conserved LSD domains were identified. Proteins with three LSD domains were highly represented in the species analyzed and were present in basal organisms. Proteins with two LSD domains were identified only in the Embryophyte clade, and proteins possessing one LSD domain were highly represented in grass species. Expression analyses of Glycine max LSD (GmLSD) genes were performed by real-time quantitative polymerase chain reaction. The results indicated that GmLSD genes are not ubiquitously expressed in soybean organs and that their expression patterns are instead organ-dependent. The expression of the majority of GmLSD genes is modulated in soybean during Phakopsora pachyrhizi infection. In addition, the expression of some GmLSD genes is modulated in plants under dehydration stress. These results suggest the involvement of GmLSD genes in the response of soybean to both biotic and abiotic stresses.


Subject(s)
Disease Resistance/genetics , Plant Diseases/genetics , Plant Proteins/genetics , Viridiplantae/genetics , Amino Acid Sequence , Gene Expression Regulation, Plant , Multigene Family , Phylogeny , Sequence Alignment , Stress, Physiological
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