Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 12 de 12
Filter
Add more filters










Publication year range
1.
J Clin Neurosci ; 33: 59-62, 2016 Nov.
Article in English | MEDLINE | ID: mdl-27519146

ABSTRACT

Malignant transformation is a rare but devastating complication following partial resection of an intracranial epidermoid cyst (EC). Time to malignant transformation is highly variable and optimal management is unclear. A literature search from 1965 to January 2016 identified manuscripts discussing clinical presentation, management, and outcome of malignant transformation of a remnant intracranial EC. One male patient diagnosed with malignant transformation of a remnant intracranial EC in our institution was also included in the study. There were 21 patients with malignant transformation of a remnant intracranial EC, including the current patient. Mean age was 51.4years (range 36 to 77) and there was a female predominance (12 women, 9 men, ratio 1.33:1). The mean time interval from partial resection of a benign intracranial EC to malignant transformation was 7.74years (range from 3months to 33years). Surgical resection of the tumor alone was the treatment of choice in 10 patients with one of them requiring a second operation and radiotherapy 2months following the first operation. Adjuvant treatment modalities were employed in 11 patients and included radiotherapy (n=4), stereotactic radiosurgery (SRS) (n=3), chemotherapy (n=1), chemotherapy combined with SRS (n=1) and with radiotherapy (n=1) and radiotherapy combined with SRS and followed by a second tumor resection (n=1). Follow-up period ranged from 1 day to 5years and 11/19 patients (57.8%) were reported dead on follow-up. Prospective studies are required to define the optimal management of malignant transformation of remnant intracranial EC.


Subject(s)
Brain Neoplasms/pathology , Brain Neoplasms/therapy , Carcinoma, Squamous Cell/pathology , Carcinoma, Squamous Cell/surgery , Cell Transformation, Neoplastic/pathology , Cerebellopontine Angle/pathology , Epidermal Cyst/pathology , Adult , Aged , Female , Humans , Male , Middle Aged
3.
J Clin Neurosci ; 32: 154-6, 2016 Oct.
Article in English | MEDLINE | ID: mdl-27349466

ABSTRACT

There is limited data on the genetic origin and natural history of cerebellar liponeurocytoma. To the best of our knowledge there has been only one report of a familial presentation of this rare entity. We report a 72-year-old female with a posterior fossa tumor presenting with progressive cerebellar signs and symptoms. The patient underwent total tumor resection via an uncomplicated sub-occipital craniotomy. Histopathologic examination was diagnostic for cerebellar liponeurocytoma. Her sister was previously treated for a similar tumor. Our report provides further evidence for the possible existence of a hereditary abnormality predisposing afflicted families to cerebellar liponeurocytoma development.


Subject(s)
Cerebellar Neoplasms/pathology , Neurocytoma/pathology , Siblings , Aged , Cerebellar Neoplasms/diagnostic imaging , Cerebellar Neoplasms/surgery , Female , Humans , Lipoma/pathology , Magnetic Resonance Imaging , Neurocytoma/diagnostic imaging , Neurocytoma/surgery , Treatment Outcome
4.
J Clin Neurosci ; 32: 141-3, 2016 Oct.
Article in English | MEDLINE | ID: mdl-27344090

ABSTRACT

We report a rare case of a 45-year-old female with an unruptured basilar artery dissecting aneurysm presenting with locked-in syndrome due to brainstem ischemia eleven months following resection of a giant cerebellopontine angle epidermoid cyst and three months after insertion of ventriculo peritoneal shunt due to hydrocephalus. The etiology of basilar artery dissection and the effect of hydrocephalus and ventricular cerebrospinal fluid drainage on disease progression in this patient are unclear. Our report suggests a possible effect of hydrocephalus and ventricular cerebrospinal fluid drainage on intracranial arterial dissection progression.


Subject(s)
Aortic Dissection/etiology , Basilar Artery/surgery , Cranial Fossa, Posterior/surgery , Epidermal Cyst/surgery , Hydrocephalus/surgery , Intracranial Aneurysm/etiology , Quadriplegia/etiology , Ventriculoperitoneal Shunt/adverse effects , Aortic Dissection/surgery , Cerebrospinal Fluid Leak/complications , Disease Progression , Epidermal Cyst/complications , Female , Humans , Hydrocephalus/complications , Intracranial Aneurysm/surgery , Middle Aged
5.
J Clin Neurosci ; 30: 120-123, 2016 Aug.
Article in English | MEDLINE | ID: mdl-27010421

ABSTRACT

Ventriculoperitoneal (VP) shunt placement is the mainstay of treatment for hydrocephalus, yet shunts remain vulnerable to a variety of complications. Although fat droplet migration into the subarachnoid space and cerebrospinal fluid pathways following craniotomy has been observed, a VP shunt obstruction with fat droplets has never been reported to our knowledge. We present the first reported case of VP shunt catheter obstruction by migratory fat droplets in a 55-year-old woman who underwent suboccipital craniotomy for removal of a metastatic tumor of the left medullocerebellar region, without fat harvesting. A VP shunt was inserted 1month later due to communicating hydrocephalus. The patient presented with gait disturbance, intermittent confusion, and pseudomeningocele 21days after shunt insertion. MRI revealed retrograde fat deposition in the ventricular system and VP shunt catheter, apparently following migration of fat droplets from the fatty soft tissue of the craniotomy site. Spinal tap revealed signs of aseptic meningitis. Steroid treatment for aseptic "lipoid" meningitis provided symptom relief. MRI 2months later revealed partial fat resorption and resolution of the pseudomeningocele. VP shunt malfunction caused by fat obstruction of the ventricular catheter should be acknowledged as a possible complication in VP shunts after craniotomy, even in the absence of fat harvesting.


Subject(s)
Adipocytes/pathology , Catheters/adverse effects , Equipment Failure , Postoperative Complications/diagnostic imaging , Ventriculoperitoneal Shunt/adverse effects , Cerebral Ventricles/diagnostic imaging , Cerebral Ventricles/surgery , Craniotomy/adverse effects , Female , Humans , Middle Aged , Postoperative Complications/etiology
6.
Acta Neurochir (Wien) ; 158(3): 451-6, 2016 Mar.
Article in English | MEDLINE | ID: mdl-26746827

ABSTRACT

BACKGROUND: Endoscopic techniques are an integral part of the neurosurgical armamentarium with a growing list of indications. We describe the purely endoscopic removal of an atypical parasagittal meningioma in a patient who could not undergo standard craniotomy due to severe scalp atrophy following childhood irradiation for tinea capitis. METHODS: A 68-year-old man in good general health presented with a parasagittal meningioma that recurred following subtotal removal and adjuvant fractionated stereotactic radiosurgery (FSR). The scalp above the tumor location was very diseased and precluded a regular craniotomy for tumor removal. A 4-cm craniotomy was made in the midline forehead, where the skin was normal. A rigid endoscope was advanced under neuronavigation through the interhemispheric fissure, which provided good access with limited retraction, until the tumor was encountered at a depth of 7-8 cm. Two surgeons performed the surgery using a "four-hands technique". The tumor was removed and the insertion area was resected and coagulated. RESULTS: The surgery was uneventful, with no coagulation or transection of major veins. A subtotal resection was achieved, and the patient recovered with no neurological deficit. CONCLUSIONS: Safe resection of parasagittal meningiomas with a purely endoscopic technique is feasible. This option needs further exploration as an alternative strategy in patients with severely atrophic scalp skin that greatly increases the risk of significant healing complications with calvarian craniotomy.


Subject(s)
Endoscopy/methods , Meningeal Neoplasms/surgery , Meningioma/surgery , Neuronavigation/methods , Aged , Humans , Male
7.
J Clin Neurosci ; 24: 135-7, 2016 Feb.
Article in English | MEDLINE | ID: mdl-26455544

ABSTRACT

Pterional craniotomy is one of the most widely used approaches in neurosurgery. The MacCarty keyhole has remained the preferred means of beginning the craniotomy to achieve a low access point; however, the bone opening may result in a residual defect and an aesthetically unpleasant depression in the periorbital area. We present our modification of the traditional technique. Instead of drilling the keyhole in the frontoperiorbital area, the classical location, we perform a 5 × 15 mm strip craniectomy at the lowest accessible point in the infratemporal fossa, corresponding to the projection of the most lateral point of the sphenoid ridge. The anterior half of this opening exposes the basal frontal dura, while the posterior half brings the temporal dura into view. This modified technique was applied in 48 pterional craniotomies performed for removal of a variety of neoplasms during 2014-2015. There were no approach-related complications. Aesthetic outcomes and patient acceptance have been good; no patient developed skin depression in the periorbital area. In our experience, craniotomy for a pterional approach with the lowest possible access to the frontotemporal skull base may be performed by drilling a narrow oblong opening, without the use of any keyhole or burr hole, to create a smaller skull defect and achieve optimal aesthetic outcomes.


Subject(s)
Craniotomy/methods , Neurosurgical Procedures/methods , Humans , Male , Skull Base/surgery , Sphenoid Bone/surgery
8.
J Clin Neurosci ; 22(4): 705-12, 2015 Apr.
Article in English | MEDLINE | ID: mdl-25752232

ABSTRACT

The sitting position during surgery is thought to provide important advantages, yet it remains controversial. We compared surgical and neurological outcomes for patients operated on in the sitting versus lateral position. Technically difficult procedures performed from the years 2001-2008 for complex lesions in the posterior fossa (vestibular schwannomas, other cerebellopontine angle tumors, foramen magnum meningiomas, brainstem cavernomas, pineal region tumors) were included. Outcomes in the two surgical positions were compared for all 243 patients (93 sitting, 38.3%; 150 lateral, 61.7%) and for 130/243 patients with vestibular schwannomas (50 sitting, 38.5%; 80 lateral, 61.5%). Sitting and lateral patient subgroups were clinically comparable. There were no surgical mortalities. The extent of removal and surgical and neurological outcomes were comparable. We found no advantage in surgical or neurological outcomes for use of the sitting or lateral surgical positions in technically difficult posterior fossa procedures. In vestibular schwannoma surgeries facial nerve preservation (House-Brackmann score 1-2) was related to extent of resection but not to surgical position. The choice of operative position should be based on lesion characteristics and the patient's preoperative medical status as well as the experience and preferences of the surgeons performing the procedure.


Subject(s)
Cranial Fossa, Posterior/surgery , Neurosurgical Procedures/methods , Patient Positioning/methods , Skull Base Neoplasms/surgery , Adolescent , Adult , Aged , Anesthesia, General/adverse effects , Child , Cranial Fossa, Posterior/diagnostic imaging , Echocardiography, Doppler , Echocardiography, Transesophageal , Female , Humans , Intraoperative Complications/epidemiology , Length of Stay , Male , Middle Aged , Monitoring, Intraoperative , Nervous System Diseases/epidemiology , Nervous System Diseases/etiology , Neuroma, Acoustic/diagnostic imaging , Neuroma, Acoustic/surgery , Postoperative Complications/epidemiology , Skull Base Neoplasms/diagnostic imaging , Treatment Outcome , Young Adult
11.
Neurosurgery ; 63(3): 476-85; discussion 485-6, 2008 Sep.
Article in English | MEDLINE | ID: mdl-18812959

ABSTRACT

OBJECTIVE: To present results of early angiographic diagnosis and endovascular treatment of traumatic intracranial aneurysms (TICA). METHODS: From June 2002 to December 2006, diagnostic angiography was performed on patients with moderate to severe traumatic brain injury that involved a cranial base fracture or a penetrating brain injury with a tract from the penetrating agent that entered at the pterional area, went through the middle cerebral artery candelabra, and crossed the midline. TICAs were treated by various endovascular techniques during the same angiographic procedure. RESULTS: Thirty-four patients with traumatic brain injury underwent angiography (25 penetrating brain injuries, nine blunt injuries); 13 TICAs were diagnosed (10 penetrating brain injuries, three blunt injuries). The Glasgow Coma Scale score at diagnosis ranged from 5 to 15. Angiography was performed for screening in eight patients and for clinical indications in five patients; 11 TICAs were diagnosed before rupture. Seven aneurysms were located on branches of the middle cerebral artery, two on pericallosal branches of the anterior cerebral artery, and four on the internal carotid artery. No recanalization was detected in 12 patients. One patient treated with a bare stent and coiling had a growing intracavernous pseudoaneurysm; therefore, internal carotid artery occlusion with extracranial-intracranial microvascular bypass was performed. Six patients refused angiographic follow-up, but computed tomographic angiography has failed to show recanalization. No patient presented with delayed bleeding (mean follow-up, 2.6 yr). There were no procedure-related complications or mortality. CONCLUSION: Early angiographic diagnosis with immediate endovascular treatment provided an effective approach for TICA detection and management. Endovascular therapy is versatile and offers a valuable alternative to surgery, allowing early aneurysm exclusion with excellent results.


Subject(s)
Brain Injuries/therapy , Catheterization/methods , Embolization, Therapeutic/methods , Intracranial Aneurysm/therapy , Adolescent , Adult , Brain Injuries/complications , Brain Injuries/diagnostic imaging , Child, Preschool , Female , Humans , Infant , Intracranial Aneurysm/diagnostic imaging , Intracranial Aneurysm/etiology , Male , Prospective Studies , Tomography, X-Ray Computed/methods , Treatment Outcome , Young Adult
12.
Surg Neurol ; 65(1): 51-4, 2006 Jan.
Article in English | MEDLINE | ID: mdl-16378858

ABSTRACT

BACKGROUND: We evaluate a new technique for plateless fixation of a bone flap after fronto-orbital craniotomy. METHODS: From September 1999 to October 2004, we performed fronto-orbital craniotomy reconstruction using the Craniofix titanium clamp in 108 consecutive patients with a variety of lesions in the anterior skull base. Postoperative computed tomographic imaging studies and clinical evaluations were performed to prospectively assess cosmetic conformity and bone flap stability and to evaluate the surgical benefit of Craniofix in these patients. RESULTS: Excellent bone flap fixation and cosmetic results were obtained in all patients 6 to 68 months (average, 36 months) after surgery. CONCLUSION: The Craniofix titanium clamp is a reliable, safe, and simple fixation device for reconstruction of fronto-orbital craniotomy.


Subject(s)
Craniotomy/instrumentation , Frontal Bone/surgery , Orbit/surgery , Plastic Surgery Procedures/instrumentation , Surgical Instruments , Craniotomy/methods , Follow-Up Studies , Humans , Plastic Surgery Procedures/methods , Titanium
SELECTION OF CITATIONS
SEARCH DETAIL
...