Anthropometric Analysis of Cuboid Bones in a South Indian Population.

Purpose Cuboid bone and its fibromuscular supports maintain the lateral longitudinal arch in weight transmission during different gait cycle phases. Morphometry of the cuboid bone is essential for designing a cuboid prosthesis for foot reconstruction and establishing an individual's biological profile. The present study aims to assess the morphology and morphometry of the cuboid bone. Materials and methods The study used 103 cuboid bones (right 50, left 53) of unknown sex. Different shapes of cuboid articular facets were observed, and the morphometric parameters such as length, breadth, and height of cuboid, and the dimensions of articular facets in cuboid (calcaneal facet, fourth and fifth metatarsal facets, ecto-cuneiform facet, navicular facet, and facet for os peroneum) were analyzed. Results The mean length, breadth, and height of the cuboid bone were 33.69 ± 2.61 mm, 25.43 ± 2.87 mm, and 23.03 ± 2.43 mm, respectively. The mean transverse and vertical diameters were 23.22 ± 2.4 mm and 15.97 ± 1.85 mm, respectively. Facet for os peroneum was observed in 74.76% and for navicular bone in 26.2%. The mean transverse and vertical diameters were 7.16 ± 2.08 and 6.78 ± 1.78 mm, respectively. The depth of the peroneal groove was 4.30 ± 1.11 mm. Conclusion The morphometric data from the present study could assist in preoperative planning and designing of prostheses for foot reconstruction, and in establishing the biological profile of an individual, which can help the anthropologists in identifying the unknown remains.

Ultrasonographic Estimation of the Gestational Age Using the Fetal Kidney Length in the Second and Third Trimesters of Pregnancy Among South Indian Antenatal Women: A Cross-Sectional Study.

Background and Objective Accurately estimating the age of the fetus is crucial to prevent morbidity and mortality for both the fetus and mother during the perinatal period. Additionally, it enables early intervention in cases of complicated pregnancies. Multiple parameters are used for the estimation of fetal gestational age (FGA) and the expected date of delivery (EDD), but no single parameter is found to be accurate and standard. This study aims to analyze the fetal kidney length (FKL) as a means to estimate gestational age and investigate the growth pattern of the fetal kidney during the early and late weeks of gestation. Furthermore, it seeks to establish correlations between FKL and gold standard parameters from the 18th week to the 38th week of gestation. Methodology This cross-sectional research was carried out after obtaining proper institutional ethical clearance. The pregnant women who came to the gynecology outpatient department (OPD) between 18 and 38 weeks were included in this study after obtaining informed consent. The fetal biometry was measured using the ultrasonographic transducer (3-5 MHz). Results The mean FKL exhibited a consistent increase throughout the entire pregnancy, ranging from 16.50 ± 2.10 to 39.20 ± 3.10 mm. The rate of increase in FKL was significant between the early weeks (18-24) of pregnancy, with insignificant growth in other weeks of gestation. The growth of the fetal kidney (length) exhibited a gradual increase from the early weeks to the late weeks of pregnancy, with a consistent growth rate of approximately 1mm per week from 18 to 35 weeks. However, in the final three weeks of pregnancy (36th, 37th, and 38th weeks), the FKL measurements were recorded as 37.90 ± 3.90, 38.90 ± 3.10, and 40.20 ± 3.10 mm, respectively. A positive correlation was noted between the FKL with all standard parameters such as biparietal diameter (BPD), femur length (FL), head circumference (HC), and abdominal circumference (AC). Conclusions This study concluded that incorporating FKL alongside standard fetal biometric parameters such as BPD, FL, HC, and AC enhanced the accuracy of calculating FGA and EDD during the early second trimester. Furthermore, it proved beneficial in diagnosing fetal anomalies during early pregnancies.

Mercuric Chloride Induced Nephrotoxicity: Ameliorative Effect of Carica papaya Leaves Confirmed by Histopathology, Immunohistochemistry, and Gene Expression Studies.

The present study analyzes the efficacy of the ethanolic extract of C. papaya leaves (ECP) against HgCl2-induced nephrotoxicity. The effects on the biochemical and percentage of body and organ weight against HgCl2-induced nephrotoxicity in female Wistar rats were studied. Wistar rats were divided into five groups with six animals in each group: control, HgCl2 (2.5 mg/kg b.w.), N-acetylcysteine (NAC 180 mg/kg) + HgCl2, ECP (300 mg/kg b.w.) + HgCl2, and ECP (600 mg/kg) + HgCl2 groups. After 28 days of study, animals were sacrificed on the 29th day to harvest the blood and kidneys for further analysis. The effect ECP was analyzed by immunohistochemistry (NGAL) and real-time PCR (KIM-1 and NGAL mRNA) in HgCl2-induced nephrotoxicity. The results revealed that the HgCl2 group showed prominent damage in the proximal tubules and glomerulus of nephrons and enormous expression of NGAL in immunohistochemistry and KIM-1 and NGAL in real-time PCR compared to the control group. The simultaneous pretreatment with NAC (180 mg/kg) and ECP (600 and 300 mg/kg) reduced renal damage and expression of NGAL in immunohistochemistry and KIM-1 and NGAL gene in real-time PCR. This study attests to the nephroprotective effect of ECP against HgCl2-induced toxicity.

Morphometric Study and Branching Patterns of External Carotid Artery Using Computed Tomography Angiography Among the South Indian Population: A Retrospective Study.

INTRODUCTION: The prime source of vascularization to the head and neck region is through the carotid arteries. The terminal branches of common carotid arteries, such as external carotid artery (ECA) and internal carotid artery (ICA), and their branches are crucial due to the wide area of distribution and variations in their branching pattern. The branching pattern and morphometry are essential for surgeons in the planning and execution of head and neck surgeries. Therefore, this study was conducted to observe the branching patterns of ECA and analyze them morphometrically. MATERIALS AND METHODS: This retrospective study includes 100 CT images, inclusive of 32 females and 68 males. The branching pattern and luminal diameter of CCA and ECA were measured and analyzed statistically. RESULTS: The luminal diameter of CCA in males were as follows: 7.4 ± 1.01 (R), 7.1 ± 0.8 (L), and in females: 7.3 ± 0.9 (R), 7 ± 0.9mm (L); and the luminal diameter of ECA in males: 5.2 ± 1.0mm (R), 5.2 ± 0.9mm (L), and in females: 5.0 ± 0.9mm (R), 5.1 ± 1.0mm (L). The level of the carotid bifurcation and ECA branching pattern was observed, and variations were commonly seen in the superior thyroid artery (STA), lingual artery (LA), and facial artery (FA).  Conclusion: The findings of the present study with regard to the external carotid artery and its branching pattern correlate with previous studies. The most common variations were observed in the superior thyroid and lingual and facial arteries. Knowledge about the morphology and branching pattern of the carotid artery is essential for procedures such as intra-arterial chemotherapy, carotid artery stenting, endarterectomy, and extra-intra cranial bypass revascularization procedure where it is harvested as a donor's vessel.

Donor Oath: Respect to the Mortal Teacher to Learn Ethics and Humanitarian Values of Anatomy.

The basic framework of the term "respect" is equality recognition. Students and teachers in academic institutions can have varying definitions of respect. Respect in the learning environment is critical for student success. This study aims to look into how students' perceptions of the human body in the anatomy lab and their respect for them can be used to promote ethical obligations, humanitarian principles, and their interrelationships. It is a descriptive, questionnaire-based study with 20 questions and a consent form that involves 250 students in the first year of MBBS. Using Microsoft Excel 2019, the data were collected, tabulated, and interpreted using descriptive statistics. The donor oath is a way to emphasize that the human body in front of them was once alive. The donor oath establishes the groundwork for future efforts to adapt existing frameworks for ethical decision-making and humanitarian values.

A Study on Sexual Dimorphism of Adult Wet Scaphoid Specimens.

Background Sexual dimorphism in human bones has mostly been confined to the study of the bony pelvis. However, considerable changes also exist in the other parts of the skeletal system. This study focuses on the differences in the morphometry of male and female adult scaphoids. Aims and objectives We aim to study the morphometry of male and female adult human scaphoids and determine the differences between the same. Materials and methods A total of 100 scaphoids were freshly dissected from both hands of 25 male and 25 female cadavers in Saveetha Medical College, Chennai, India. The soft tissues were loosened using 5% potassium hydroxide (KOH) solution. Further, the soft tissues were removed by meticulous dissection. For the measurements, vernier calipers and threads for circumference measurement were used. Results The morphometric parameters included length, proximal width, width of the middle part (waist), distal width and circumference of the waist, and circumference of the tubercle in scaphoids. Statistical differences were found in most of the parameters. Conclusion A statistically significant difference exists between the morphometric measurements of male and female adult scaphoids, which may prove helpful in the fracture fixation of the scaphoid, as scaphoid fracture has a risk of avascular necrosis.

Morphometric Study of the Intracranial Segment of the Vertebral Artery.

Background The vertebral artery (VA) forms the caudal part of the circle of Willis and is responsible for one-third of the blood supply of the cerebellum, pons, middle ear, and the upper part of the spinal cord and its meninges. The highest potential risk of injury to VA during cervical pedicle screw implantation is at C3 and then at C6. Knowledge about the morphometry of VA provides a better understanding of clinical conditions such as vertebra basilar insufficiency (VBI). Similarly, the knowledge of variation in the VA is needed during cervical pedicle screw implantation, which possesses the highest potential risk to VA at the C3 level. The origin of the vertebral artery from the aortic arch reached the upper cervical vertebra than the vertebral artery of subclavian origin. The length of the VA is greater on the left side than the right-side artery. Understanding and reporting of the same are essential to creating awareness that can aid in endarterectomy, angioplasty, and radiological procedures. Variations are noted in morphometry between sides. Aim To determine the morphometry of the vertebral artery (VA) with emphasis on the fourth segment (V4) and its variations using computed tomography angiogram (CTA). Materials and methods This present retrospective study was conducted in the Departments of Anatomy and Radiology and Imaging Sciences, Saveetha Medical College and Hospital. Participants were patients who took a head and neck CT for various clinical reasons. About 50 CT images, 33 male and 17 females, were selected from the archives. The length, diameter, and entry level of VA were studied. The data were tabulated and statistically analyzed. Result The mean length of VA was 24.49 ± 3.02 (cm) on the left side and 24.28 ± 3.91 (cm) on the right side in female subjects and was found to be 22.78 ± 1.7 (cm) on the left side and 21.5 ± 2.7 (cm) on the right side in male subjects. The mean diameter of VA at the level of the foramen magnum was 0.32 ± 0.05 (cm) on the right side and 0.322 ± 0.07 (cm) on the left side in females, 0.3 ± 0.064 (cm) on the left side and 0.26 ± 0.086 (cm) on the right side in males. Conclusion The length of VA was found to be statistically more on the left side than on the right side. The variations in morphometry seen can aid in various surgical and radiological procedures.

Views on virtual education during the COVID-19 pandemic among medical and paramedical students in India.

The COVID-19 pandemic has made the educational institutions to implement the mandatory virtual learning in medical education. It is undeniable that electronic gadget aided learning have a significant role to play during a pandemic. Both faculty and students are getting accustomed to this 'New Normalcy'. Therefore, it is of interest to determine the effectiveness and perception of virtual teaching and learning during the COVID 19 pandemic. A cross-sectional study was conducted in which 336 medical and 336 paramedical students of both the genders with age group of 17 - 21 years participated. The data obtained were analyzed using the SPSS software. The shift from class room teaching to virtual learning has led to many health issues among students such as eye strain, anxiety, depression, musculoskeletal problems and obesity. The students also had inadequate time to interact with faculties. Data shows that virtual learning an alternative mode to traditional method during a pandemic.

Morphometric Analysis of Achilles Tendon Structure and Its Significance: A Cadaveric Study.

INTRODUCTION: Achilles tendon is crucial for gait, and chronic Achilles tendinopathy can have a substantial impact on an individual's work and active involvement in physical or sports activity, and overall quality of life. OBJECTIVES: This research was to determine the macroscopic and microscopic anatomy of Achilles tendons in cadavers. MATERIALS AND METHODS: This experimental study was conducted in the Department of Anatomy, Saveetha Medical College, Thandalam, from March to August 2022. A total of 60 formalin-perfused cadavers (38 males and 22 females) were dissected to study their morphometry (length, width, thickness) and histology. The data was tabulated in MS excel and analyzed statistically using unpaired 't-test and one-way ANOVA in SPSS Software 17.0 (IBM Corp., Armonk, NY). RESULTS: The mean length of the Achilles tendon was significantly higher in males than in females and similarly, the length on the right side was significantly higher than on the left side (p<0.005). The width and circumference were statistically higher in females than, males whereas, the histological features were similar in both males and females. CONCLUSION: The better understanding of Achilles tendon morphometry in cadavers always aids in the diagnosis and surgical repair of tendinopathy, rupture, and degenerative change. The knowledge will be helpful for the surgeons during the repair and reconstruction of the injured tendon.