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1.
Ann Noninvasive Electrocardiol ; 25(1): e12689, 2020 01.
Article in English | MEDLINE | ID: mdl-31498498

ABSTRACT

The diagnosis of Brugada syndrome is usually made with a typical ECG pattern. However, different disorders can emulate this pattern (Brugada phenocopies). Pathophysiologic mechanisms underlying this phenomenon remain controversial. We describe the development of type-1 Brugada ECG pattern associated with extensive coronary steal effect during myocardial perfusion scintigraphy. Proximal occlusion of the right coronary artery and severe proximal stenosis in distally occluded left circumflex artery were confirmed by coronary angiogram. Brugada ECG pattern can be a reversible sign associated with inferior left ventricular and right ventricular ischemia. Its presence during acute ischemia deserves appropriate risk stratification.


Subject(s)
Brugada Syndrome/complications , Brugada Syndrome/diagnosis , Electrocardiography/methods , Myocardial Ischemia/complications , Brugada Syndrome/physiopathology , Coronary Angiography/methods , Diagnosis, Differential , Heart/physiopathology , Humans , Male , Middle Aged , Myocardial Ischemia/physiopathology , Tomography, Emission-Computed, Single-Photon/methods
3.
Medicina (B Aires) ; 77(2): 130-134, 2017.
Article in Spanish | MEDLINE | ID: mdl-28463221

ABSTRACT

The protocols using vasodilators to induce ischemia on myocardial perfusion scintigraphy have shown a high diagnostic accuracy and a very low incidence of serious complications. However, the physiological significance and diagnostic value of various electrocardiographic changes associated with vasodilator stress has not been deeply evaluated beyond the ST-segment. Five clinical cases presenting morphological distortion of the T-wave in electrocardiographic chest leads associated with varying degrees of perfusion defects are described, discussing potential contributions of these changes to the diagnosis and quantification of myocardial ischemia in imaging studies using vasodilator stress.


Subject(s)
Ischemia/diagnostic imaging , Myocardial Perfusion Imaging/methods , Stress, Physiological/drug effects , Vasodilator Agents/administration & dosage , Aged , Electrocardiography , Female , Humans , Ischemia/chemically induced , Ischemia/physiopathology , Male , Middle Aged
4.
Medicina (B.Aires) ; 77(2): 130-134, Apr. 2017. ilus, graf, tab
Article in Spanish | LILACS | ID: biblio-894447

ABSTRACT

Los protocolos que utilizan vasodilatadores para inducir isquemia en la centellografía de perfusión miocárdica han demostrado una exactitud diagnóstica elevada e incidencia muy baja de complicaciones graves. Sin embargo, el significado fisiológico y valor diagnóstico de diversas alteraciones electrocardiográficas asociadas al estrés vasodilatador ha sido escasamente evaluado más allá del segmento ST. Describimos cinco pacientes que presentan distorsión morfológica de la onda T en derivaciones electrocardiográficas torácicas asociada a diversos defectos de perfusión, discutiendo los potenciales aportes de estos cambios al diagnóstico y cuantificación de la isquemia miocárdica en los estudios de imagen que utilizan estrés con vasodilatadores.


The protocols using vasodilators to induce ischemia on myocardial perfusion scintigraphy have shown a high diagnostic accuracy and a very low incidence of serious complications. However, the physiological significance and diagnostic value of various electrocardiographic changes associated with vasodilator stress has not been deeply evaluated beyond the ST-segment. Five clinical cases presenting morphological distortion of the T-wave in electrocardiographic chest leads associated with varying degrees of perfusion defects are described, discussing potential contributions of these changes to the diagnosis and quantification of myocardial ischemia in imaging studies using vasodilator stress.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Stress, Physiological/drug effects , Vasodilator Agents/administration & dosage , Myocardial Perfusion Imaging/methods , Ischemia/diagnostic imaging , Electrocardiography , Ischemia/physiopathology , Ischemia/chemically induced
6.
Medwave ; 15(9): e6285, 2015 Oct 16.
Article in English, Spanish | MEDLINE | ID: mdl-26523696

ABSTRACT

A proper characterization of frequency-dependent bundle branch blocks can provide useful prognostic information in some clinical situations. Often, this physiological event may be due to an extensive damage of infrahisian system, which poses a high risk of developing advanced atrioventricular block requiring pacemaker implantation. We describe the case of a 62 year-old man with chronic ischemic heart disease who exhibited alternating tachycardia-dependent bundle branch block during stress test. We discuss the main prognostic implications of this unusual event in the context of systolic dysfunction.


Una caracterización correcta de los bloqueos de rama dependientes de frecuencia, puede proporcionar información relevante en ciertas situaciones clínicas. A menudo, este evento fisiológico puede evidenciar la presencia de un daño extenso del sistema de conducción infrahisiano con riesgo elevado de bloqueo aurículo-ventricular avanzado y necesidad de implante de marcapasos. Describimos el caso de un hombre de 62 años con cardiopatía isquémica crónica, que exhibió un bloqueo de rama bilateral alternante taquicardia-dependiente durante el esfuerzo ergométrico, discutiendo las principales implicancias pronósticas de este evento inusual en el contexto de la disfunción sistólica.


Subject(s)
Bundle-Branch Block/physiopathology , Myocardial Ischemia/physiopathology , Tachycardia/physiopathology , Bundle-Branch Block/diagnosis , Exercise Test , Humans , Male , Middle Aged , Prognosis , Systole , Tachycardia/diagnosis , Ventricular Dysfunction, Left/diagnosis , Ventricular Dysfunction, Left/physiopathology
8.
Rev. urug. cardiol ; 28(3): 345-354, dic. 2013. ilus, graf, tab
Article in Spanish | LILACS-Express | LILACS | ID: lil-754265

ABSTRACT

Antecedentes: la aparición de ángor y/o infradesnivel del segmento ST durante la prueba ergométrica graduada (PEG) permite hacer el diagnóstico presuntivo de cardiopatía isquémica (CI). Otros cambios electrocardiográficos podrían ser de utilidad. Uno de ellos es el score de Atenas (SDA), que relaciona los cambios de amplitud del complejo QRS en reposo y en el posesfuerzo inmediato (PEI). El propósito de nuestro estudio es determinar la validez del SDA en el diagnóstico de CI; secundariamente, evaluar su correlación con la clase funcional (CF) del paciente y el incremento del doble producto (DP) durante la PEG. Material y método: se realizó un análisis retrospectivo en 75 pacientes remitidos a estudio de perfusión miocárdica (EPM) sensibilizados con PEG. En 25 pacientes se diagnosticó isquemia por la presencia de defectos reversibles de grado moderado a severo. Resultados: en los valores medios del SDA no se hallaron diferencias estadísticamente significativas entre los grupos. En EPM (+) fue -0,16 mm (DS±4,39) y en EPM (-) 1,88 mm (±4,3) (p=0,062). En cambio, existen diferencias significativas en los pacientes con CF I (>7 MET) o un DP>2,5 veces el basal. En los primeros, el SDA fue -3,73 mm (±6,83) en los EPM (+) y 5,2 mm (±4,34) en los EPM (-) (p<0,02). En aquellos con incremento del DP >2,5 veces, el SDA fue -1,57 mm (±6,99) en los EPM (+) y 3,64 mm (±4,72) en los EPM (-) (p<0,03). Conclusiones: el SDA tiene utilidad para predecir isquemia moderada a severa en el EPM en aquellos pacientes en CF I o que incrementen dos veces y media el DP en la PEG.


Background: the onset of angina and/or ST segment displacement during exercise testing (ET) is useful in the diagnosis of ischemic heart disease (IHD). Other changes in the electrocardiogram also may be of diagnostic value. One of them is the QRS or Athens Score (SDA) based in changes in the amplitude of the QRS complex recorded at rest and immediately post-stress. The purpose of this study is to determine the validity of the SDA in the diagnosis of IHD, secondarily, to evaluate SDA results according the functional class (CF) and the increment in the double product (DP) during the ET. Material and method: we conducted a retrospective study in 75 patients referred to perform myocardial perfusion imaging (EPM) with ET. The diagnosis of ischemia was done in 25 patients with moderate to severe reversible defects. Results: the SDA mean value expressed in mm (±SD) was -0,16 ± 4,39 for EPM (+) and 1,88 ± 4,3 for EPM (-), the difference was non-significant (p=0.062). However, there were significant differences in patients with CF I (> 7 MET) or a DP >2,5 times the baseline. In the first, the SDA was -3,73 ± 6,83 in EPM (+) and 5,2 ± 4,34 in the EPM (-) (p< 0,02). In those with DP increased >2.5 times, the SDA was -1,57 ± 6,99 in the EPM (+) and 3,64 ± 4,72 EPM (-) (p<0,03). Conclusion:the SDA have diagnostic utility for predicting moderate to severe ischemia in the EPM in those patients with CF I or an increment of the DP >2,5 in the ET.

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