[Male with sudden-onset dementia associated with long lasting diarrhea as manifestations of Whipple's disease]. / Varón con demencia de aparición brusca, asociada a diarrea de larga evolución como manifestaciones de la enfermedad de Whipple.

A case of a 55-year old male with Whipple's disease who consulted for dementia (aggressivity, memory loss of recent events, sleep rhythm disturbances) is presented. Furthermore, the patient had referred changes in intestinal movement four years beforehand in addition to erratic arthralgias. Response to treatment (trimethoprim-sulfamethoxazole for one year) was favorable with resolution of both the neurologic and gastrointestinal pictures. The radiologic alterations of this entity are reviewed and suggest that this disease should be considered as a cause of dementia.