ABSTRACT
AIM: Chronic venous disease (CVD) is a well-defined and known disorder which impact on related-health quality of life (QoL). However, individuals factors which determinate quality of life on CVD are not well defined. The purposes of this study were to describe the QoL in patients with CVD and examine socio-demographical and clinical factors which influence QoL METHODS: One thousand five hundred sixty patients with CVD were evaluated. We calculated for each patient two disease-specific severity scores: The "C" grade (clinical) of the CEAP classification and the Venous Clinical Severity Score (VCSS). Additionally, two QoL questionnaires were recorded: Short-Form Health Survey (SF-12) and Chronic Lower Limb Venous Insufficiency Questionnaire (CIVIQ-20). Two multivariate logistic regression analyses (SF-12 and CIVIQ-20 model) were conducted to determine whether demographic and clinical variables were independently associated with QoL. RESULTS: Both QoL questionnaires indicated that the QoL decreased significantly (P<0.05) as the C grade of CEAP increased. Each increase of 0.10 in VCSS score represented 2% worsening in QoL as measured by CIVIQ-20. Three factors were strongly associated with poor QoL on SF-12: increasing age, prior superficial venous thrombosis (SVT) or prior deep venous thrombosis. In the specific disease CIVIQ-20 questionnaire three factors (higher age, prior SVT and higher weight) were strongly associated with decrease QoL. CONCLUSION: Increasing disease severity by VCSS is associated with reductions in QoL. Subgroup analysis indicates that there are several significant individual determinants of worsening QoL.
Subject(s)
Quality of Life , Varicose Veins/psychology , Venous Insufficiency/psychology , Adult , Aged , Chronic Disease , Cost of Illness , Cross-Sectional Studies , Female , Humans , Logistic Models , Male , Middle Aged , Multivariate Analysis , Prognosis , Prospective Studies , Risk Factors , Severity of Illness Index , Spain/epidemiology , Surveys and Questionnaires , Varicose Veins/diagnosis , Varicose Veins/epidemiology , Venous Insufficiency/diagnosis , Venous Insufficiency/epidemiologyABSTRACT
AIM: The present study aimed to demonstrate how the quality of life (QoL) perceived by patients with chronic venous disease (CVD) is correlated with the severity of their disease objectively assessed by primary care physician. MATERIAL AND METHODS: A total of 1560 patients with CVD were evaluated using four measurement instruments: CEAP clinical classification, Venous Clinical Severity Score (VCSS), SF-12 Health Survey and Chronic Lower Limb Venous Insufficiency Questionnaire (CIVIQ-20). Statistical correlations between these tools were analysed using Spearman's coefficient. RESULTS: Patients were distributed in C0, 58 (3.7%); C1, 243 (15.6%); C2, 328 (21.0%); C3, 357 (22.9%); C4, 368 (23.6%); C5, 136 (8.7%); and C6, 70 (4.5%). The VCSS score for the whole cohort was 0.89 ± 0.53. The correlation between CEAP and VCSS was moderately strong (r = 0.69). The overall QoL scores measured by SF and CIVIQ were 56.84 ± 19.63 and 65.11 ± 14.35, respectively. The correlation between the two QoL questionnaires was very strong (r = 0.81). The correlations of the SF and CIVIQ with the VCSS were moderately strong (r = -0.47 and -0.48). The correlations between QoL questionnaires and CEAP were moderate and lower than those with VSCC. CONCLUSIONS: While there is correlation between VCSS, CEAP, modified CIVIQ and venous ultrasound findings, subgroup analysis indicates that this correlation is driven by different components of VCSS compared with the other venous assessment tools. Patients' opinions about their disease are correlated with those assessed by primary care physicians.
Subject(s)
Patients/psychology , Physicians, Primary Care/psychology , Quality of Life , Surveys and Questionnaires , Venous Insufficiency/diagnosis , Adolescent , Adult , Aged , Aged, 80 and over , Chronic Disease , Cross-Sectional Studies , Female , Humans , Male , Middle Aged , Predictive Value of Tests , Severity of Illness Index , Spain , Ultrasonography , Venous Insufficiency/diagnostic imaging , Venous Insufficiency/psychology , Young AdultABSTRACT
Introducción. La degeneración neoplásica de una úlcera por hipertensión venosa es una complicación descrita como poco frecuente en la bibliografía. De los dos tipos histológicos con que puede cursar esta malignización, el carcinoma basocelular constituye, frente al de células escamosas, la forma más infrecuente. Caso clínico. Se presenta un caso de úlcera venosa complicada con un carcinoma basocelular en un enfermo de 86 años, resuelto mediante exéresis quirúrgica asociada a fleboextracción segmentaria, y se revisa la bibliografía, analizando las discordancias observadas en la misma sobre la asociación de úlcera venosa y neoplasia (AU)
Subject(s)
Aged , Male , Humans , Carcinoma, Basal Cell/complications , Carcinoma, Basal Cell/diagnosis , Ulcer/complications , Ulcer/diagnosis , Venous Pressure , Hypertension/complications , Hypertension/diagnosis , Stomach Ulcer/complications , Dermatitis/complications , Edema/complications , Carcinoma, Basal Cell/radiotherapy , Carcinoma, Basal Cell/pathology , Lung Diseases, Obstructive/complications , Lung Diseases, Obstructive/diagnosisABSTRACT
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