ABSTRACT
We present a case report of a 6-year-old female child, admitted in the Pediatric Clinic, diagnosed with Aplastic Constitutional Hereditary Anaemia (Fanconi Anaemia). On ophthalmic examination, on the left eye were noted important macular edema and a big preretinal haemorrhage of 4 DP situated on the posterior pole. The treatment of the systemic condition established the involution of the ophthalmic manifestations.
Subject(s)
Anemia, Aplastic/complications , Retinal Hemorrhage/etiology , Anemia, Aplastic/diagnosis , Anemia, Aplastic/drug therapy , Anemia, Aplastic/genetics , Child , Female , Fundus Oculi , Humans , Prognosis , Retinal Hemorrhage/diagnosis , Retinal Hemorrhage/drug therapy , Treatment OutcomeABSTRACT
PURPOSE: The aim of this paper is to observe the corneal neurotrophic ulcers in patients with ophthalmic and systemic diseases associated with impairment of the sensory innervation of the cornea. METHODS: We have performed a retrospective study using a lot of patients with corneal neurotrophic ulcers, admitted in Ophthalmology Clinic in 2003-2006. We have analyzed the etiopathogenic factors that have determined the corneal trophic ulcers, the treatment and the complications occurred. RESULTS: The study spot-lighted two main causes responsible for the corneal trophic ulcers: ocular and systemic disorders. For many patients the etiopathogenic factor is multiple. CONCLUSIONS: 1. Corneal neurotrophic ulcer is a severe complication of an ophthalmic or a systemic disorder. 2. The moderate outcome of ophthalmic complications require early treatment, adjusted for each patient. 3. Prevention of the corneal neurotrophic ulcers is the best method of treatment.
Subject(s)
Cornea/innervation , Corneal Ulcer/diagnosis , Corneal Ulcer/etiology , Contact Lenses , Cornea/pathology , Corneal Transplantation , Corneal Ulcer/prevention & control , Corneal Ulcer/therapy , Humans , Ophthalmic Solutions/administration & dosage , Retrospective Studies , Wound HealingABSTRACT
The paper present a clinic and histological study, including all cases of uveal malignant tumours, hospitalized in Ophthalmological Clinic of Craiova in the last 15 years. The follow-up period of cases were 4 years. The diagnosis was established by clinic and paraclinic examination (imaging methods-- MRI, CT, Echo) and histologic examination. The histologic examination has been done for all cases. There were investigated several parametres: tumour cytology, the level of pigmentation, intravascular embolus, sclera infiltration, vascular invasion, vascular pattern, tumoral necrosis, mitotic activity. The histologic aspects of tumoral progression were: the high level mitotic activity, high surface area of intratumoral necrosis, the infiltrative process to the vessels, sclera, and ciliary body. The arcuat and network vascular patterns were involved in the systemic metastasis and local invasion. The most predominant type of cellularity related with a severe evolution of cases were the epithelioid cells and the mixed type cells.
Subject(s)
Melanoma/diagnosis , Uveal Neoplasms/diagnosis , Adult , Aged , Aged, 80 and over , Female , Follow-Up Studies , Humans , Male , Melanoma/pathology , Melanoma/surgery , Middle Aged , Retrospective Studies , Uveal Neoplasms/pathology , Uveal Neoplasms/surgeryABSTRACT
The paper realized the retrospective evaluation of all cases of neovascular glaucoma hospitalized in Clinic of Ophthalmology of Craiova in the last 15 years. Neovascular secondary glaucoma represents 3,9% of all glaucomas. The most important etiologic factors were the central venous occlusion, diabetic retinopathy, carotid occlusion, intraocular tumors, chronic uveitis, Fuchs heterochromy. Neovascular secondary glaucoma is characterized by important hypoxic tissues destructions, presented of all levels that lead to neovessels formation with irreversible anatomic and functional losing of ocular globe. The identification of neovascular glaucoma causes and their treatment is important to prevent that diseases.
