[The content of biologically active substances in the margin of a stomach ulcer being treated with a copper-vapor laser]. / Soderzhanie biologicheski aktivnykh veshchestv v krae iazvy zheludka pri lechenii lazerom na parakh medi.

A study was made of the effect of laser therapy on the content of she biologically active substances serotonin, histamine, PGE2 and PGF2 alpha as well as on the adenylate cyclase system--adenylate cyclase activity and cGMP content. Direct exposure to laser produced an appreciable increase of the content of serotonin and histamine, PGE2 and PGF2 alpha, cAMP and of adenylate cyclase activity. On the healing of ulcerous defect after 5-6 sessions of laser therapy a decrease of the content of serotonin, a rise of histamine, PGE2, PGF2 alpha, cAMP accumulation and adenylate cyclase activation were recorded.

[Effect of laser irradiation of different intensities on the processes of healing of stomach ulcers]. / Vliianie lazernogo izlucheniia razlichnoi moshchnosti na protsessy zazhivleniia iazv zheludka.

Patients with stubborn peptic ulcers were exposed to copper vapor laser of various intensities with similar irradiation energy. The best therapeutic effect (more rapid ulcer healing) was achieved when ulcer bottom and edges were exposed to laser of higher intensity; the effect is explained by a higher stimulation of inflammation and a more rapid and clear-cut restructuring of connective-tissue stroma on ulcer bottom.

[Biogenic amines and cyclic nucleotides in the laser therapy of long-term nonhealing stomach ulcers]. / Biogennye aminy i tsiklicheskie nukleotidy pri lazeroterapii dlitel'no ne zazhivaiushchikh iazv zheludka.

A study is presented of the effect of copper vapors laser therapy on the content of biogenic amines--serotonin and histamine and the state of adenylcyclase (AC) system (content of cAMP, cGMP and AC activity) at the edge of the gastric ulcer. Direct effect of laser radiation (single dose 10--15 J.) produced a significant increase of serotonin, histamine, cAMP, AC activity and an insignificant increase of cGMP. Healing of the ulcerative defect after 5--6 laser therapy sessions was followed by a reduction of the content of serotonin, increase of histamine, cAMP and AC activity. The authors discuss the biostimulating effect of laser radiation by influencing the inflammatory-proliferative processes in the epitheliocytes in prolonged nonhealing gastric ulcers.

[The effect of laser therapy on the mechanisms for generating healing in long-term nonhealing stomach ulcers]. / Vliianie lazeroterapii na nekotorye mekhanizmy sanogeneza dlitel'no nezazhivaiushchikh iazv zheludka.

A study was made of the effect of copper laser therapy on the content of PGE and PGF2 alpha and on the adenylate cyclase system (cAMP, cGMP and adenylate cyclase content) in patients with gastric ulcer. Seventy patients with indolent (from 3 months to 2 years) gastric ulcers were examined. The patients were assigned into 2 groups: group I received drug therapy combined with the influence of laser on copper vapours on the ulcerous surface (a single radiation dose 10 to 15 J). As compared to group I, the patients of group II manifested a considerable rise of the content of cAMP and prostaglandins, as well as adenylate cyclase activation in the gastric mucosa. Nonspecific biostimulating action of laser radiation exercised via the influence on the dysregenerative processes in the epitheliocytes of long nonhealing ulcer edges is under discussion.

[Effectiveness of the treatment of chronic non-healing stomach ulcers using copper vapor laser]. / Effektivnost' lecheniia dlitel'no nezazhivaiushchikh iazv zheludka lazerom na parakh medi.

A group of patients with chronic gastric ulcers received a course of laser treatment with the use of laser on copper vapours. Gastric ulcer was exposed to radiation once in the course of 5 days, the single dose being equal to 10-15 J. Complete healing of the ulcerous defect was attained in 100 out of 110 patients examined. The results of laser therapy were found to be influenced by certain clinical characteristics, namely by age, ulcer size, duration of the last disease exacerbation, and acid-secreting function of the stomach.

Investigation of vibrational relaxation in the hydrogen chloride chemical laser.

The gain dependence on time of the HCl chemical laser was measured and calculated. Comparison of the calculated and measured results enables one to determine the constant of HCl-HCl deactivation which is found to be within (0.2-9) 10(12) cm(3) mole(-1) sec(-1).