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2.
C R Acad Hebd Seances Acad Sci D ; 280(25): 2905-8, 1975 Jun 30.
Article in French | MEDLINE | ID: mdl-808329

ABSTRACT

A transformed and malignant cell line was obtained by treatment of secondary hamster embryo cells with 7-methyl benz(a)anthracene (10 mug/ml of medium). Later on these cells acquired the capacity to grow spontaneously in suspension and form "spheroids". The evolution of this cell line showed similarities between the carcinogenic process in vitro and in vivo.


Subject(s)
Benz(a)Anthracenes , Cell Transformation, Neoplastic , Neoplasms, Experimental/pathology , Cell Line , Chromosome Aberrations , Neoplasm Transplantation , Neoplasms, Experimental/genetics , Transplantation, Homologous
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