Sclerotherapy treatment of varicose veins.

The protocol for clinical examination and diagnostic evaluation of patients with varicose veins is described in this article. The specific techniques of sclerotherapy for treatment of the saphenofemoral junction, sapheno-popliteal junction, incompetent perforators, and truncular and reticular varices is outlined. Recommended dosages for both saphenous and nonsaphenous varicose veins are listed in order to help the practitioner achieve satisfactory sclerotherapy.

Gram-negative bacterial toe web infection: successful treatment with a new third generation cephalosporin.

Fifteen patients with gram-negative bacterial toe web infections were treated for 1 week with intramuscular cefoperazone, a broad-spectrum third generation cephalosporin. Initial bacterial cultures in eleven patients (73%) grew more than one gram-negative organism. Pseudomonas aeruginosa was the most frequent isolate. All bacteria isolated were sensitive to cefoperazone (Cefobid). Swelling, redness, and flow of exudate resolved within 1 week of antibiotic administration. By day 7 there was no evidence of inflammation, and denuded areas had begun to re-epithelialize. Side effects were mild and did not require cessation of therapy. This antibiotic causes rapid resolution of a disease which previously required prolonged hospitalizations.