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Euro Surveill ; 19(48): 20974, 2014 Dec 04.
Article in English | MEDLINE | ID: mdl-25496570

ABSTRACT

We report a case of meningoencephalitis caused by Toscana virus (TOSV) with central facial paralysis lasting over two days acquired in south-eastern France. The patient was not febrile either before or during the course of the disease. The diagnosis was established by both real-time RT-PCR and virus isolation with complete genome sequencing. This case emphasises the need to consider TOSV in non-febrile neurological syndromes in people living in or having travelled to the Mediterranean area.


Subject(s)
Bunyaviridae Infections/diagnosis , Facial Paralysis/etiology , Meningoencephalitis/diagnosis , Sandfly fever Naples virus/isolation & purification , Acyclovir/therapeutic use , Adult , Amoxicillin/therapeutic use , Animals , Anti-Bacterial Agents/therapeutic use , Antiviral Agents/therapeutic use , Bunyaviridae Infections/drug therapy , Ceftriaxone/therapeutic use , Female , France , Genome, Viral/genetics , Humans , Insect Vectors/virology , Meningoencephalitis/virology , RNA, Viral/genetics , RNA, Viral/isolation & purification , Reverse Transcriptase Polymerase Chain Reaction , Sandfly fever Naples virus/genetics , Sequence Analysis, RNA , Treatment Outcome
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