ABSTRACT
BACKGROUND: Type 2 Diabetes Mellitus (T2DM) is a chronic disease that is increasing the number of cases worldwide. The treatments currently used have not worked as expected. Alternative and complementary medicines were inserted in health services, especially in primary care, as an attempt to minimize risks and help control diseases such as diabetes. Among the herbal medicines used stands out cinnamon, which can serve as an adjuvant in the control of diabetes. OBJECTIVE: To analyze the effectiveness of 3 grams of cinnamon (Cinnamomum verum) per day for 90 days in reducing glycemic and lipid levels in adults with T2DM compared with placebo METHODS:: A randomized, double-blind, placebo-controlled, phase II trial, which will be conducted at basic health units in the city of Parnaíba, state of Piauí, Brazil. In total, 130 people diagnosed with T2DM, followed at health units, with hemoglobin A1c >â6.5%, and using oral antidiabetic medicines, are expected to participate in the study. The intervention will last for 3 months, and each participant will receive a total of 3 bottles containing 120 capsules in each bottle of cinnamon or placebo. Each person should take 4 capsules daily, for 90 days. The patients will be distributed into the 2 groups by performing block randomization (nâ=â6) at a ratio of 1:1 according to a code generated by a software. Assessments of socioeconomic, clinical, lifestyle, anthropometric, and laboratory variables will be performed in 2 separate visits. DISCUSSION: This study will be the first to investigate cinnamon to reduce glycemic, lipid, and anthropometric levels in Brazil. In case of favorable results, this therapy may be used as an alternative or additional medicine in cases where only oral antidiabetic agents are used and can promote the use of the product to minimize future complications of patients with diabetes and people who do not have the disease. TRIAL REGISTRATION: RBR-2KKB6D, registered on December 11th, 2018.
Subject(s)
Blood Glucose/drug effects , Cinnamomum zeylanicum , Diabetes Mellitus, Type 2/drug therapy , Hypoglycemic Agents/administration & dosage , Lipids/blood , Adolescent , Adult , Aged , Aged, 80 and over , Clinical Trials, Phase II as Topic , Diabetes Mellitus, Type 2/blood , Double-Blind Method , Female , Glycated Hemoglobin/drug effects , Humans , Male , Middle Aged , Randomized Controlled Trials as Topic , Young AdultABSTRACT
Objetivou-se identificar alterações físicas, neurológicas e vasculares nos pés de diabéticos. Foram avaliadas 250 pessoas, coletando dados mediante inspeção, sensibilidade tátil, vibratória e térmica, reflexo de Aquiles e palpação de pulsos. Os resultados mostraram que 84% eram mulheres, 55% com idade entre 18 e 60 anos, 40% com mais de 10 anos de doença e 66% não praticavam atividade física, 81% apresentavam deformidades, calos e fissuras, 24% sensibilidade tátil e térmica comprometidas, 20% sensibilidade vibratória anormal, 11% ausência do reflexo de Aquiles, 3% pulsação pediosa ausente e 7% pulsação tibial ausente. Destaca-se a associação entre idade e exames de sensibilidade tátil, reflexo de Aquiles e pulsação tibial. Foram significativas as associações entre o teste do reflexo de Aquiles e as variáveis tempo de doença e prática de exercícios. Conclui-se que a maioria apresenta sinais clínicos sugestivos de pé em risco, representando um alerta para os profissionais de saúde envolvidos com a clientela...
This study was intended to identify physical, neurological and vascular alterations in the diabetics' feet. It evaluated 250 people, collecting data by means of inspection, tactile, vibratory and thermal sensibility, AchillesÆ reflex and pulses presence. The results showed that 84% were women, 55% with age between 18 and 60 years, 40% with more than 10 years of disease and 66% didn't practice physical activity. 81% presented deformities, calluses and fissures, committed 24% tactile and thermal sensibility, 20% abnormal vibratory sensibility, 11% absence of Achilles' reflex, 3% pedious pulsation is absent and 7% tibial pulsation is absent. There were out association among age and exams of tactile sensibility, Achilles' reflex and tibial pulsation. The associations between the test of the Achilles' reflex and the variable time of disease and practice of exercises were significant. It was concluded that most present suggestive clinical signs of foot in risk, representing an alert for the health professionals involved with the clientele...
Se objetivó identificar alteraciones físicas, neurologícas y vasculares en los pies de los diabéticos. Se evaluaron 250 personas, recolectando datos mediante la inspección, sensibilidad táctil, vibratória y térmica, reflejo de Aquiles y la palpación de los pulsos. Los resultados señalaron que 84% eran mujeres, 55% con edad dentre 18 y 60 años, 40% además de 10 años de enfermedad y 66% no practicaban actividad física, 81% presentaban deformidades, callos y fisuras, 24% sensibilidad táctil y térmica implicadas, 20% sensibilidad vibratória anormal, 11% ausencia del reflejo de Aquiles, 3% pulsación pediosa ausente y un 7% pulsación tibial ausente. Se ha destacado la asociación entre edad y examenes de sensibilidad tactil, reflejo de Aquiles y pulsación tibial. Fueron significativas las asociaciones entre el examen del reflejo de Aquiles y las variables tiempo de enfermedad y práctica de actividades. Se concluye que la mayoría presenta signos clínicos sugerstivos de pie con riesgo, presentando una alerta para los profesionales de la salud comprometidos con la clientela...
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Diabetes Mellitus , Diabetic Neuropathies , Diabetic Foot , Process Assessment, Health Care , Health Profile , Health PersonnelABSTRACT
Objetivou-se identificar, na população de servidores de um hospital universitário, aqueles em risco de desenvolver Diabetes mellitus (DM)...
Subject(s)
Humans , Risk Factors , Diabetes Mellitus , Health Personnel , Brazil , Hospitals, University , Surveys and QuestionnairesABSTRACT
O estudo objetiva redigir diagnósticos de enfermagem para gestantes diabéticas, baseados nos padrões de resposta humana, visando ao planejamento das intervenções de enfermagem...
