Subject(s)
Borohydrides/toxicity , Hemoglobins/analysis , Leukocyte Count/drug effects , Sulfhydryl Compounds/toxicity , Sulfides/toxicity , Animals , Borohydrides/pharmacokinetics , Brain Neoplasms/metabolism , Dose-Response Relationship, Drug , Female , Glioma/metabolism , Kidney Function Tests , Liver/drug effects , Liver/pathology , Mice , Mice, Inbred Strains , Software , Sulfhydryl Compounds/pharmacokinetics , Sulfides/pharmacokineticsABSTRACT
The usefulness of nocturnal penile tumescence with stamps to measure erections during sleep has been evaluated under laboratory conditions and compared to strain gauge recording. If the ring of stamps does not break a diagnosis of organic dysfunction is supported. However, if breakage occurs at the perforations no diagnostic conclusion can be made. The diagnostic importance of nocturnal penile tumescence with stamps is limited.
Subject(s)
Penis/physiology , Sleep/physiology , Adult , Aged , Circadian Rhythm , Humans , Male , Middle Aged , PlethysmographyABSTRACT
Circumferentially assessed penile responses less than 10 per cent of maximal tumescence usually are regarded as random variation. However, several investigators have hypothesized that one of the initial responses to sexual stimulation is a lengthening of the penile shaft. Circumferential measurements detect this lengthening as a decrease in penile circumference. Two experiments were conducted to investigate this hypothesis. During the first experiment penile circumference changes were monitored at 2 levels of voltage sensitivity. A reliable voltage decrease was observed for all subjects immediately after the introduction of an erotic stimulus. In the second experiment the penis was videotaped to determine the magnitude of penile lengthening that occurred during the circumferential decrease. The results indicated that a substantial penile length change occurred (mean 34.5 per cent of the total erection length change) before any diameter increase was evident. A small number of impotent patients with a clear etiology were investigated using this new test. The results suggest that penile elongation occurs in the absence of full erections in patients with psychogenic impotence, while circumferential and longitudinal changes do not appear after visual erotic stimuli in organically impotent patients. The penile elongation test may prove useful in the etiological screening of impotent patients.
Subject(s)
Erectile Dysfunction/physiopathology , Penis/physiology , Adult , Humans , MaleABSTRACT
An erectometer for the measurement of sleep erections is described. Comparative studies using simultaneously strain gauges and the new device indicate that it possesses a significant potential for valid measurement of the circumferential increase that may occur during sleep. Because of its reliability, simplicity and low cost the erectometer is proposed as a screening procedure or as a diagnostic alternative when sleep laboratory facilities are not feasible.
