ABSTRACT
Modern knowledge concerning adhesive disease of abdominal cavity is imperfect, that's why it is necessary to discover new and effective methods of investigation of the disease to improve prophylactic and treatment measures. There was studied up the distribution of the HLA system antigens in adhesive disease, markers of predisposition to the disease occurrence were revealed. The HLA typing results in 52 patients of Georgian nationality, suffering adhesive disease of abdominal cavity, are presented. Trustworthy increase of frequency of the HLA antigens Al, B15, B21 revealing was noted in patients in comparison with such in control group. According to the relative risk criterion, maximal possibility of the adhesive illness occurrence was connected with HLA-B15 antigen. It may be concluded that in Georgian population antigen HLA-B15 constitutes a genetic marker of the adhesive illness occurrence.
Subject(s)
HLA-B Antigens/analysis , Peritoneal Diseases/immunology , Biomarkers/analysis , Female , HLA-B Antigens/immunology , HLA-B15 Antigen , Humans , Male , Peritoneal Diseases/surgery , Predictive Value of Tests , Tissue Adhesions/immunology , Tissue Adhesions/surgeryABSTRACT
The article analyses the results of treatment of 150 patients with purulent diseases of the soft tissues of various localization, in which after surgical treatment the purulent focus immobilized trypsin (50 patients), trypsin with lysozyme immobilized on gauze (50 patients), and antiseptics (50 patients) were used for topical treatment of the formed wounds. The results of the treatment showed that topical prolonged enzyme therapy of purulent wounds with the use of trypsin immobilized on gauze and that with lysozyme promotes cleansing of the wounds, reduces microbial dissemination, intensifies reparative processes, and reduces the terms of treatment.
Subject(s)
Enzymes, Immobilized/therapeutic use , Surgical Wound Infection/prevention & control , Adolescent , Adult , Aged , Aged, 80 and over , Humans , Middle Aged , Suppuration/therapy , Time Factors , Wound Healing/drug effectsABSTRACT
The results of treatment of 370 patients with purulent soft tissue diseases have shown that laseroenzymotherapy of the suppurating wounds contributed to their rapid cleaning, maintenance of microbial colonization at a stable low level, activation of reparative processes. This permitted to prepare a wound surface for closure at the nearest days after the operation.
