1.
J Immunol
; 144(3): 960-3, 1990 Feb 01.
Article
in English
| MEDLINE
| ID: mdl-1688593
ABSTRACT
IFN-alpha, -beta, and -gamma protect murine fibroblasts from lysis by vesicular stomatitis virus. In this report we show that culture supernatants derived from a Th cell clone of the TH2-type completely block the protective effects of the IFN. The active component in inhibiting IFN is identified to be IL-4. rIL-4 has similar effects as the T cell supernatant.
Subject(s)
Interferons/antagonists & inhibitors , Interleukin-4/pharmacology , T-Lymphocytes, Helper-Inducer/physiology , Viral Interference/drug effects , Animals , Cells, Cultured , Cytopathogenic Effect, Viral , In Vitro Techniques , Interferon Type I/antagonists & inhibitors , Interferon-gamma/antagonists & inhibitors , L Cells , Mice , Recombinant Proteins , Vesicular stomatitis Indiana virus/pathogenicity
2.
Zentralbl Veterinarmed B
; 35(8): 601-9, 1988 Oct.
Article
in German
| MEDLINE
| ID: mdl-3195261
