ABSTRACT
OBJECTIVE: to analyze a hepatitis C virus (HCV) microelimination strategy targeting vulnerable populations and the influence of the pandemic on its maintenance and outcomes. METHODS: in 2018, the Hepatology Unit implemented an HCV microelimination strategy for patients attending drug addiction care centers and Psychiatry Units such as the Alcoholism Treatment Unit. These centers reported suspected or confirmed cases of HCV infection directly to the hepatologists, who, after reviewing the clinical records, cite those patients if necessary. RESULTS: from June 2018 to February 2020, hepatologists were consulted on 37 anti-HCV positive patients, 31 of them were from Drug Addiction Care Centers, 5 from the Alcoholism Disorders Unit and 1 from the Department of Psychiatry. Fibrosis stage: F0-F1, 18 (50%); F2, 9 (25%); F3, 2 (4.2%); F4, 8 (20.8%). Female sex, 6 (16.7%). Required attending: Yes, 27 (73%). 25 (92.6%) went. Outpatient consultation: 10 (27%). Required treatment: 19 (51.3%). Sustained virological response: 19 (100%). Fibrosis stage of treated patients: F0-F1, 13 (68%); F2, 2 (11%); F3, 1 (5%); F4, 3 (16%). Patients from the Psychiatry Department during 2021: 11. 9 (82%) do not need to attend; 2 (18%): their situation is unknown. CONCLUSIONS: sustained communication with centers that care for populations at risk of active HCV infection is needed to detect cases, increase adherence to treatment, and rescue patients who require screening for hepatocarcinoma.
Subject(s)
Alcoholism , Hepatitis C, Chronic , Hepatitis C , Liver Neoplasms , Substance-Related Disorders , Female , Humans , Antiviral Agents/therapeutic use , Hepacivirus , Hepatitis C/epidemiology , Hepatitis C/prevention & control , Hepatitis C/drug therapy , Hepatitis C, Chronic/drug therapy , Liver Cirrhosis/pathology , Liver Neoplasms/drug therapy , Pandemics , Substance-Related Disorders/drug therapy , Vulnerable Populations , MaleABSTRACT
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Subject(s)
Humans , Female , Middle Aged , Hepatitis E/drug therapy , Hepatitis, Chronic/drug therapy , Ribavirin/therapeutic use , Hepatitis E virus/pathogenicityABSTRACT
Los tumores de células epiteliodes perivasculares son tumores de células epiteliales vasculares con características inmunohistoquímicas de músculo liso y células melanocíticas. Los gastrointestinales son infrecuentes. El tratamiento es quirúrgico aunque existen datos que indican buena respuesta a la rapamicina (AU)
Perivascular epithelioid cell tumors (PEComa) are tumors of perivascular epithelioid cells with immunohistochemical features of smooth muscle and melanocytic tumors. The PEComa of the gastrointestinal tract is rare. The treatment is surgical, although there are data that suggest a good response to rapamycin (AU)
Subject(s)
Humans , Male , Adult , Ileal Neoplasms/diagnosis , Ileal Neoplasms/drug therapy , Ileal Neoplasms/pathology , Perivascular Epithelioid Cell Neoplasms/surgery , Sirolimus/therapeutic use , Perivascular Epithelioid Cell Neoplasms/diagnosis , Perivascular Epithelioid Cell Neoplasms/pathology , Immunohistochemistry/instrumentation , Immunohistochemistry/methodsABSTRACT
Perivascular epithelioid cell tumors (PEComa) are tumors of perivascular epithelioid cells with immunohistochemical features of smooth muscle and melanocytic tumors. The PEComa of the gastrointestinal tract is rare. The treatment is surgical, although there are data that suggest a good response to rapamycin.
Subject(s)
Ileal Neoplasms/diagnostic imaging , Perivascular Epithelioid Cell Neoplasms/diagnostic imaging , Humans , Ileal Neoplasms/surgery , Ileum/diagnostic imaging , Ileum/pathology , Male , Perivascular Epithelioid Cell Neoplasms/surgery , Tomography, X-Ray Computed , Treatment Outcome , Young AdultSubject(s)
Antiviral Agents/therapeutic use , Hepatitis E virus/isolation & purification , Hepatitis E/drug therapy , Hepatitis, Chronic/drug therapy , Ribavirin/therapeutic use , Antineoplastic Combined Chemotherapy Protocols/adverse effects , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Ascites/etiology , Enterobacteriaceae Infections/complications , Enterobacteriaceae Infections/microbiology , Female , Hafnia alvei/isolation & purification , Hematopoietic Stem Cell Transplantation , Hepatitis E/etiology , Hepatitis, Chronic/etiology , Hepatitis, Chronic/virology , Humans , Immunocompromised Host , Immunosuppressive Agents/adverse effects , Immunosuppressive Agents/therapeutic use , Lymphoma, Non-Hodgkin/complications , Middle Aged , Rituximab/therapeutic use , Transplantation, AutologousSubject(s)
Carcinoma, Renal Cell , Gastrointestinal Stromal Tumors , Jejunal Neoplasms , Kidney Neoplasms , Neoplasms, Multiple Primary , Aged , Carcinoma, Renal Cell/diagnosis , Carcinoma, Renal Cell/surgery , Gastrointestinal Stromal Tumors/diagnosis , Gastrointestinal Stromal Tumors/surgery , Humans , Jejunal Neoplasms/diagnosis , Jejunal Neoplasms/surgery , Kidney Neoplasms/diagnosis , Kidney Neoplasms/surgery , Male , Neoplasms, Multiple Primary/diagnosis , Neoplasms, Multiple Primary/surgerySubject(s)
Humans , Male , Middle Aged , Gastrointestinal Stromal Tumors/diagnosis , Gastrointestinal Stromal Tumors/drug therapy , Chondrosarcoma, Mesenchymal/complications , Chondrosarcoma, Mesenchymal/diagnosis , Gastrointestinal Stromal Tumors/physiopathology , Neoplasms/complications , Neoplasms/pathologyABSTRACT
No disponible
No disponible
Subject(s)
Humans , Male , Adult , Cholestasis, Intrahepatic/chemically induced , Cetirizine/adverse effects , Hyperbilirubinemia/chemically inducedSubject(s)
Cholangiopancreatography, Endoscopic Retrograde/adverse effects , Endoscopes , Hematoma/etiology , Liver Diseases/etiology , Liver/blood supply , Postoperative Hemorrhage/etiology , Sphincterotomy, Endoscopic/adverse effects , Aged , Antibiotic Prophylaxis , Blood Vessels/injuries , Cholangiopancreatography, Endoscopic Retrograde/instrumentation , Choledocholithiasis/surgery , Equipment Design , Female , Hematoma/diagnostic imaging , Humans , Hydrophobic and Hydrophilic Interactions , Liver/diagnostic imaging , Liver Diseases/diagnostic imaging , Postoperative Hemorrhage/diagnostic imaging , Rupture/etiology , Tomography, X-Ray ComputedABSTRACT
No disponible
