ABSTRACT
OBJETIVO: Presentamos dos casos de pacientes diagnosticados de tumor hematológico que presentan recidiva a nivel testicular, realizamos la revisión de la literatura en relación a lo infrecuente de dicha patología. MÉTODOS: Revisión retrospectiva de la historia clínica de dos pacientes diagnosticados de neoplasias hematológicas (Leucemia Mieloblástica Aguda y Mieloma múltiple) con aparición de recidiva a nivel testicular. Revisamos el manejo y resultado tras tratamiento mediante orquiectomía bilateral. RESULTADO: Caso 1: Paciente diagnosticado de Leucemia mieloblástica aguda tratada mediante trasplante alogénico. Dos años después el paciente refiere aumento del tamaño testicular. En estudios complementarios se sospecha recidiva a nivel testicular que tras orquiectomía se confirma. Actualmente se encuentra a la espera de tratamiento quimioterápico previo a nuevo trasplante alogénico. Caso 2: Paciente diagnosticado de Mieloma Múltiple que inicia tratamiento poliquimioterápico sin respuesta, se realiza trasplante alogénico. Tras cinco meses de remisión completa se evidencian signos de recidiva sistémica realizándose estudio para nuevo trasplante. Durante el mismo se objetiva posible recidiva a nivel testicular. Tras pruebas complementarias se realiza orquiectomía bilateral y se confirma el diagnóstico. Actualmente el paciente se encuentra en protocolo de trasplante alogénico tras tratamiento radio y quimioterápico. CONCLUSIONES: Actualmente el porcentaje de mortalidad, en los casos de recidiva a nivel testicular secundaria a neoplasia hematológica, ha disminuido pese al marcado aumento de su incidencia. Esto se debe, como en nuestros casos, a un diagnóstico precoz y al uso combinado de quimioterapia, radioterapia y cirugía. Esto se logra a través de un trabajo interdisciplinario entre urólogos, hematólogos, oncólogos y radioterapeutas
OBJECTIVE: We report two cases of patients with a previous diagnosis of hematologic tumor who present with testicular recurrence, and we carry out a review of the literature regarding the infrequency of this pathology. METHODS: We present a retrospective review of the medical records of two patients diagnosed with hematologic malignancies (acute myelogenous leukemia and multiple myeloma) with occurrence of relapse in the testicle. We reviewed the management and outcome after treatment with bilateral orchiectomy. RESULTS: Case 1: The patient was diagnosed with acute myeloid leukemia and treated with an allogeneic transplant. Two years later, the patient reported an increase in testicular size. The complementary studies lead us to suspect a testicular recurrence that was confirmed after orchiectomy. Currently, the patient awaits the start of a chemotherapy treatment prior to a new allogeneic transplant. Case 2: Patient with the diagnosis of multiple myeloma who started a polychemotherapy treatment without response and underwent allogeneic transplant. After five months with complete remission, there were signs of systemic recurrence, and a study for a new transplant was carried out. During the study, potential testicular recurrence was observed. After a batch of complementary tests, bilateral orchiectomy was performed and the diagnosis was confirmed. Currently, the patient is undergoing an allogeneic transplant protocol after radiotherapy and chemotherapy treatment. CONCLUSIONS: Currently the mortality rate in cases of relapse of hematologic malignancy in the testicle has declined despite the sharp rise in its incidence. This is because of, as in our case, early diagnosis and the combined use of chemotherapy, radiotherapy and surgery. This has been achieved through an interdisciplinary collaboration of urologists, hematologists, oncologists and radiotherapists
Subject(s)
Humans , Male , Middle Aged , Hematologic Neoplasms/diagnosis , Hematologic Neoplasms/pathology , Hematologic Neoplasms/therapy , Neoplasm Recurrence, Local/diagnosis , Neoplasm Recurrence, Local/pathology , Neoplasm Recurrence, Local/mortality , Testicular Neoplasms/drug therapy , Testicular Neoplasms/radiotherapy , Testicular Neoplasms/surgery , Early Diagnosis , Orchiectomy/instrumentation , Orchiectomy/methods , Radiotherapy/instrumentation , Radiotherapy/methods , Drug Therapy/instrumentation , Drug Therapy/methods , Chemotherapy, Adjuvant/instrumentation , Chemotherapy, Adjuvant/methods , Chemotherapy, Adjuvant , Retrospective StudiesABSTRACT
INTRODUCTION AND OBJECTIVES: To report one case of prostatic abscess and subdural empyema by Staphylococcus aureus. METHODS: We describe the case of a 51 year old male patient who was diagnosed of prostatic abscess and subdural empyema by Staphilococcus aureus. We use clinical presentation and physical exploration based on rectal digital examination, as diagnostic approach method. And computerized axial tomography and transrectal ultrasonography, which allows the guided needle drainage of the abscess, as diagnostic confirmation methods. RESULTS: The clinical picture resolved with the transrectal ultrasonography guided needle aspiration of the abscess and conservative treatment with antibiotics and urinary diversion. CONCLUSIONS: Prostatic abscess is an uncommon entity nowadays. Provided the great variety of symptoms, a great degree of clinical suspicion is needed for the diagnosis, and once it is got it, immediate aggressive treatment must be initiated. Transrectal ultrasonography allows not only the diagnosis, but also the drainage of the abscess. The culture of the obtained material identifies the etiological agent and the most specific antibiotic therapy.
Subject(s)
Abscess/complications , Empyema, Subdural/etiology , Prostatic Diseases/complications , Staphylococcal Infections/complications , Abscess/diagnosis , Abscess/therapy , Humans , Male , Middle Aged , Prostatic Diseases/diagnosis , Prostatic Diseases/therapy , Staphylococcal Infections/diagnosis , Staphylococcal Infections/therapyABSTRACT
Introducción y objetivo: Presentamos el caso de un paciente con absceso prostático y empiema subdural por Staphilococo aureus. Material y método: Descripción de un caso de un paciente de 51 años de edad diagnosticado de absceso prostático y empiema subdural por Staphilococo aureus. Utilizamos como método de aproximación diagnóstica la sospecha clínica y la exploración física mediante tacto rectal. Como métodos de confirmación diagnóstica, pruebas de imagen, como la tomografía axial computerizada y la ecografía transrectal, que permite además el drenaje del material purulento. Resultados: El cuadro se resolvió con ecografía transrectal y punción-drenaje de la colección y con tratamiento conservador en base a antibioterapia y derivación urinaria. Conclusiones: El absceso prostático es en la actualidad una patología poco frecuente. Dada la gran variedad de presentación de esta entidad, hay que tener un alto grado de sospecha para su diagnóstico y una vez realizado comenzar un tratamiento inmediato agresivo. La ecografía transrectal permite, no sólo el diagnóstico, sino también la punción-drenaje del contenido purulento. El cultivo de las muestras obtenidas identifica el agente causante y la antibioterapia más adecuada
Introduction and objectives: To report one case of prostatic abscess and subdural empyema by Staphylococcus aureus. Methods: We describe the case of a 51 year old male patient who was diagnosed of prostatic abscess and subdural empyema by Staphilococcus aureus. We use clinical presentation and physical exploration based on rectal digital examination, as diagnostic approach method. And computerized axial tomography and transrectal ultrasonography, which allows the guided needle drainage of the abscess, as diagnostic confirmation methods. Results: The clinical picture resolved with the transrectal ultrasonography guided needle aspiration of the abscess and conservative treatment with antibiotics and urinary diversion. Conclusions: Prostatic abscess is an uncommon entity nowadays. Provided the great variety of symptoms, a great degree of clinical suspicion is needed for the diagnosis, and once it is got it, immediate aggressive treatment must be initiated. Transrectal ultrasonography allows not only the diagnosis, but also the drainage of the abscess. The culture of the obtained material identifies the etiological agent and the most specific antibiotic therapy
