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1.

Aleukemic "leukemia cutis" of monocytic lineage.

Gil-Mateo, M P; Miquel, F J; Piris, M A; Sánchez, M; Martin-Aragonés, G.

J Am Acad Dermatol ; 36(5 Pt 2): 837-40, 1997 May.

Article in English | MEDLINE | ID: mdl-9146562

ABSTRACT

We describe aleukemic leukemia cutis (ALC) in a 50-year-old woman who presented with numerous skin nodular lesions and lack of peripheral blood and bone marrow involvement until late in the evolution of her disease. We emphasize the value of immunohistochemical studies to distinguish ALC from cutaneous large cell lymphoma.

Subject(s)

Leukemia, Myeloid , Leukemia , Leukemic Infiltration , Skin/pathology , Diagnosis, Differential , Female , Humans , Leukemia/diagnosis , Leukemia/pathology , Leukemia, Myeloid/diagnosis , Leukemia, Myeloid/pathology , Lymphoma, Large B-Cell, Diffuse/diagnosis , Middle Aged , Skin Neoplasms/diagnosis

2.

[Comparative analysis of 3 therapeutic regimens based on the combination of an anthracycline and cytosine arabinoside for remission induction in myeloblastic leukemia]. / Análisis comparativo de tres regímenes terapéuticos basados en la combinación de una antraciclina y arabinósido de citosina para la inducción a la remisión en la leucemia mieloblástica.

Sanz, M A; Lorenzo, J I; Sanz, G F; Martín Aragonés, G; Rafecas, F J; Martínez, J A; Gomis, F.

Sangre (Barc) ; 33(6): 497-504, 1988 Dec.

Article in Spanish | MEDLINE | ID: mdl-3247626

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Leukemia, Myeloid, Acute/drug therapy , Adolescent , Adult , Aged , Aged, 80 and over , Child , Cytarabine/therapeutic use , Daunorubicin/administration & dosage , Doxorubicin/administration & dosage , Female , Humans , Leukemia, Myeloid, Acute/pathology , Male , Middle Aged , Prednisone/administration & dosage , Remission Induction , Thioguanine/administration & dosage , Vincristine/administration & dosage

3.

[Acute microgranular promyelocytic leukemia (M3 variant). Study of 14 patients]. / Leucemia promielocítica aguda microgranular (M3 variante). Estudio de 14 pacientes.

Jarque, I; Sanz, M A; Martín-Aragonés, G; Sanz, G; Rafecas, F J; Lorenzo, J I; Martínez, J; Pastor, E; Gomis, F; Pérez-Sirvent, M L.

Sangre (Barc) ; 33(2): 102-7, 1988 Apr.

Article in Spanish | MEDLINE | ID: mdl-3165223

Subject(s)

Leukemia, Myeloid, Acute/pathology , Adolescent , Adult , Aged , Antineoplastic Agents/therapeutic use , Biomarkers, Tumor/analysis , Child , Chromosomes, Human, Pair 15/ultrastructure , Chromosomes, Human, Pair 17/ultrastructure , Female , Hemorrhagic Disorders/etiology , Humans , Leukemia, Myeloid, Acute/blood , Leukemia, Myeloid, Acute/drug therapy , Male , Middle Aged , Translocation, Genetic

4.

[Prognostic factors and predictive models of the different causes of failure in te induction of remission in acute nonlymphoblastic leukemia]. / Factores pronósticos y modelos predictivos de las distintas causas de fracaso en la inducción en la leucemia aguda no limfoblástica.

Lorenzo, J I; Sanz, M A; Martín-Aragonés, G; Rafecas, F J; Martínez, J A; Sanz, G; Gomis, F.

Med Clin (Barc) ; 90(4): 151-5, 1988 Jan 30.

Article in Spanish | MEDLINE | ID: mdl-3352348

Subject(s)

Leukemia/drug therapy , Acute Disease , Adult , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Female , Humans , Leukemia/mortality , Male , Middle Aged , Prognosis , Regression Analysis , Remission Induction , Risk Factors

5.

High-dose cytosine arabinoside and mitoxantrone in high-risk acute nonlymphoblastic leukemia.

Sanz, M A; Martínez, J; Borrego, D; Martín-Aragonés, G; Lorenzo, I; Sanz, G; Sayas, M J; Jarque, I; Pastor, E; Rafecas, J.

Semin Oncol ; 14(2 Suppl 1): 18-20, 1987 Jun.

Article in English | MEDLINE | ID: mdl-3589692

Subject(s)

Cytarabine/administration & dosage , Leukemia/drug therapy , Mitoxantrone/administration & dosage , Acute Disease , Adult , Antineoplastic Combined Chemotherapy Protocols/administration & dosage , Cytarabine/adverse effects , Dose-Response Relationship, Drug , Drug Administration Schedule , Female , Humans , Male , Middle Aged , Mitoxantrone/adverse effects

6.

[Analysis of prognostic factors and predictive models of response to induction chemotherapy in acute non-lymphoblastic leukemia]. / Análisis de factores pronósticos y modelos predictivos de respuesta a la quimioterapia de inducción en la leucemia aguda no linfoblástica.

Lorenzo, J I; Martín-Aragonés, G; Rafecas, F J; Martínez, J A; Sanz, G; Gomis, F; Sanz, M A.

Med Clin (Barc) ; 89(4): 135-40, 1987 Jun 20.

Article in Spanish | MEDLINE | ID: mdl-3626658

Subject(s)

Antineoplastic Agents/therapeutic use , Leukemia/drug therapy , Acute Disease , Adult , Female , Humans , Male , Middle Aged , Prognosis

7.

[High-dose cytosine arabinoside and L-asparaginase in the treatment of refractory or recurrent acute non-lymphoblastic leukemia]. / Arabinósido de citosina a altas dosis (Ara-C-AD) y L-asparaginasa (L-ASP) en el tratamiento de la leucemia aguda no linfoblástica refractaria o en recidiva.

Sanz, M A; Borrego, D; Martín-Aragonés, G; Martínez, J A; Lorenzo, I; Sanz, G; Sayas, M J; Jarque, I; Pastor, E; Rafecas, J.

Sangre (Barc) ; 32(4): 476-81, 1987.

Article in Spanish | MEDLINE | ID: mdl-3660187

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Leukemia/drug therapy , Neoplasm Recurrence, Local/drug therapy , Acute Disease , Adolescent , Adult , Aged , Asparaginase/administration & dosage , Asparaginase/adverse effects , Child , Cytarabine/administration & dosage , Cytarabine/adverse effects , Female , Humans , Male , Middle Aged , Remission Induction

8.

Teniposide and cytarabine combination chemotherapy in the treatment of relapsed adolescent and adult acute lymphoblastic leukemia.

Sanz, G F; Sanz, M A; Rafecas, F J; Martínez, J A; Martín-Aragonés, G; Marty, M L.

Cancer Treat Rep ; 70(11): 1321-3, 1986 Nov.

Article in English | MEDLINE | ID: mdl-3464352

ABSTRACT

Nineteen adolescents and adults with relapsed acute lymphoblastic leukemia (ALL) were treated with teniposide (VM-26) plus cytarabine (ara-C). Eight patients (42%) achieved complete remission. Infection and bleeding secondary to myelosuppression were the most serious complications seen. Responders received periodic reinductions with VM-26 and ara-C, but all relapsed within 16 weeks from remission. Our data demonstrate the effectiveness of combination chemotherapy with VM-26 plus ara-C in adolescent and adult ALL in relapse and suggest testing of this combination in first-line protocols. For remission maintenance, the association of other drug combinations is necessary.

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Leukemia, Lymphoid/drug therapy , Acute Disease , Adolescent , Adult , Antineoplastic Combined Chemotherapy Protocols/adverse effects , Cytarabine/administration & dosage , Female , Hematologic Diseases/chemically induced , Humans , Leukemia, Lymphoid/pathology , Male , Nervous System Neoplasms/prevention & control , Teniposide/administration & dosage

9.

[Acute promyelocytic leukemia. Analysis and results of treatment with daunorubicin in 29 patients]. / Leucemia promielocítica aguda. Análisis y resultados del tratamiento con daunorrubicina en 29 pacientes.

Jarque, I; Sanz, M A; Martín-Aragonés, G; Martínez, J; Rafecas, F J; Sanz, G F; Lorenzo, J I; Sayas, M J; Gomis, F; Marty, M L.

Sangre (Barc) ; 31(4): 411-24, 1986.

Article in Spanish | MEDLINE | ID: mdl-3466374

Subject(s)

Daunorubicin/therapeutic use , Leukemia, Myeloid, Acute/drug therapy , Adolescent , Adult , Aged , Child , Female , Humans , Male , Middle Aged

10.

[Treatment of acute adult myeloblastic leukemia with intensive chemotherapy]. / Tratamiento de la leucemia mieloblástica aguda del adulto con quimioterapia intensiva.

Sayas, M J; Sanz, M A; Martín-Aragonés, G; Javier Rafecas, F; Martínez, J A; Lorenzo, I J; Sanz, G F; Gomis, F; Marty, M L.

Sangre (Barc) ; 31(6): 718-29, 1986.

Article in Spanish | MEDLINE | ID: mdl-3470955

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Leukemia, Myeloid, Acute/drug therapy , Adult , Antineoplastic Combined Chemotherapy Protocols/adverse effects , Busulfan/administration & dosage , Carmustine/administration & dosage , Combined Modality Therapy , Cyclophosphamide/administration & dosage , Cytarabine/administration & dosage , Doxorubicin/administration & dosage , Drug Combinations/administration & dosage , Drug Evaluation , Female , Humans , Leukemia, Myeloid, Acute/radiotherapy , Male , Meningeal Neoplasms/prevention & control , Mercaptopurine/administration & dosage , Methotrexate/administration & dosage , Middle Aged , Mitoguazone/administration & dosage , Prednisone/administration & dosage , Thioguanine/administration & dosage , Vincristine/administration & dosage

11.

[Spontaneous pneumomediastinum in a young patient with acute lymphoblastic leukemia]. / Neumomediastino espontáneo en paciente joven con leucemia linfoblástica aguda.

Jarque, I; Martín Aragonés, G; Sánz, M A.

Sangre (Barc) ; 31(6): 772-3, 1986.

Article in Spanish | MEDLINE | ID: mdl-3470957

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/adverse effects , Leukemia, Lymphoid/complications , Mediastinal Emphysema/etiology , Vomiting/complications , Adolescent , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Female , Humans , Leukemia, Lymphoid/drug therapy , Vomiting/chemically induced

12.

[Prognostic value of the FAB classification in acute nonlymphocytic leukemia]. / Valor pronóstico de la clasificación FAB en la LANL.

Sanz, M A; Martín-Aragonés, G; Ignacio Lorenzo, J.

Sangre (Barc) ; 31(5): 602-3, 1986.

Article in Spanish | MEDLINE | ID: mdl-3810415

Subject(s)

Leukemia/classification , Humans , Prognosis

13.

[Experience with the use of Hickman's catheter for venous access in patients with acute myeloblastic leukemia]. / Experiencia con el uso del catéter de Hickman para el acceso venoso de pacientes con leucemia mieloblástica aguda.

Sanz, M A; Such, M; Martínez, J A; Martín-Aragonés, G; Lorenzo, J I; Sanz, G; Sayas, M J; Rafecas, F J; Marty, M L.

Sangre (Barc) ; 30(5): 889-98, 1985.

Article in Spanish | MEDLINE | ID: mdl-3867161

Subject(s)

Catheterization , Leukemia, Myeloid, Acute/drug therapy , Adolescent , Adult , Aged , Antineoplastic Agents/administration & dosage , Bacterial Infections/etiology , Catheterization/adverse effects , Catheterization/instrumentation , Child , Female , Humans , Male , Middle Aged

14.

[Induction of remission by sequential treatment with cytosine arabinoside (araC/high dose) and L-asparaginase]. / Inducción a la remisión con tratamiento secuencial de arabinósido de citosina (Ara-C/AD) y L-asparaginasa.

Martín-Aragonés, G; Sanz, M A; Martínez, J A; Rafecas, F J; Gomis, F; Lorenzo, I; Sanz, G; Marty, M L.

Sangre (Barc) ; 30(1): 15-21, 1985.

Article in Spanish | MEDLINE | ID: mdl-3859023

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Asparaginase/therapeutic use , Cytarabine/therapeutic use , Leukemia/drug therapy , Acute Disease , Adolescent , Adult , Aged , Asparaginase/administration & dosage , Child , Cytarabine/administration & dosage , Drug Administration Schedule , Female , Humans , Leukemia, Lymphoid/drug therapy , Male , Middle Aged , Podophyllotoxin/therapeutic use

15.

[Diagnosis and treatment of infection in the support of the neutropenic patient]. / Diagnóstico y tratamiento de la infección en el soporte del paciente neutropénico.

Rafecas, F J; Sanz, M A; Martín-Aragones, G; Martínez, J A; Sayas, M J; Marty, M L.

Sangre (Barc) ; 30(4-B): 501-14, 1985.

Article in Spanish | MEDLINE | ID: mdl-4081964

Subject(s)

Agranulocytosis/complications , Bacterial Infections/diagnosis , Neutropenia/complications , Anti-Bacterial Agents/therapeutic use , Bacterial Infections/drug therapy , Drug Administration Schedule , Drug Therapy, Combination , Granulocytes/transplantation , Humans

16.

[Acute leukemia of hypoplastic presentation with myeloid and lymphoid markers and monosomy 7]. / Leucemia aguda de presentación hipoplásica con marcadores mieloides y linfoides y monosomía 7.

Gomis, F; Sanz, M A; Amigó, V; Pérez-Sirvent, M L; Sanz, G; Martín-Aragonés, G.

Sangre (Barc) ; 30(5): 913-6, 1985.

Article in Spanish | MEDLINE | ID: mdl-4089753

Subject(s)

Leukemia/pathology , Acute Disease , Adolescent , Bone Marrow/pathology , Chromosomes, Human, 6-12 and X , Female , Hematopoietic System/pathology , Humans , Leukemia/genetics , Monosomy

17.

[Therapeutic results in non-T non-B acute lymphoblastic leukemia in the adult with intensive postremission chemotherapy]. / Resultados terapéuticos en leucemia linfoblástica aguda no-T no-B del adulto con quimioterapia intensiva postremisión.

Sanz, G; Sanz, M A; Rafecas, F J; Martínez, J A; Amigó, V; Martín-Aragonés, G; Gomis, F; Lorenzo, I; Marty, M L.

Sangre (Barc) ; 29(6): 1018-29, 1984.

Article in Spanish | MEDLINE | ID: mdl-6598234

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Leukemia, Lymphoid/drug therapy , Actuarial Analysis , Adolescent , Adult , Aged , Antineoplastic Combined Chemotherapy Protocols/adverse effects , Cyclophosphamide/administration & dosage , Female , Humans , Injections, Spinal , Male , Mercaptopurine/administration & dosage , Methotrexate/administration & dosage , Middle Aged , Prednisone/administration & dosage , Vincristine/administration & dosage

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