ABSTRACT
OBJECTIVE: To asses the role of Gastroesophageal reflux in the genesis of laryngeal granulomas. PATIENTS AND METHODS: Prospective series of 7 patients diagnosed of posterior laryngeal granuloma, 5 were male, and 2 female, ages ranging between 46 and 65 years, (only three with symptoms of gastroesophageal reflux), who followed an antireflux protocol (recommendations, omeprazol 20 mg, cisapride 20 mg, almagato 4000 mg daily). RESULTS: All cases did well, showing complete healing of the larynx 60 days after the beginning of treatment. CONCLUSIONS: Gastroesophageal reflux is an important factor in the genesis of posterior laryngeal granulomas. It seems appropriate to start an antireflux regimen before surgery, which can be chosen for non responders or cases with severe respiratory symptoms, hoarseness, or for definitive diagnosis.
Subject(s)
Granuloma, Respiratory Tract/drug therapy , Laryngeal Diseases/drug therapy , Aged , Aluminum Hydroxide , Antacids , Anti-Ulcer Agents , Carbonates , Cisapride , Female , Gastroesophageal Reflux/drug therapy , Humans , Magnesium Hydroxide , Male , Middle Aged , Omeprazole , Prospective StudiesABSTRACT
Objetivo: Evaluar el papel del reflujo gastroesofágico en la etiología de los granulomas de laringe. Material y método: Estudio prospectivo en 7 pacientes diagnosticados de granuloma posterior de laringe, 5 varones y 2 mujeres, con edades comprendidas entre los 46 y los 65 años (3 con síntomas de reflujo gastroesofágico), que se sometieron a tratamiento antirreflujo (medidas y recomendaciones antirreflujo, omeprazol 20 mg, cisaprida 20 mg y almagato 4000 mg diariamente). Resultados: Todos respondieron favorablemente al tratamiento, constatándose la desaparición de las lesiones a los 60 días del inicio del mismo. Conclusiones: El reflujo gastroesofágico es un importante factor etiológico en la patogénesis de los granulomas de la laringe. Es correcto aplicar un tratamiento médico antirreflujo inicial reservando la cirugía para los pacientes que no respondan o toleren la medicación y para los que generen dudas diagnósticas o un importante compromiso respiratorio o de la fonación (AU)
OBJECTIVE: To asses the role of Gastroesophageal reflux in the genesis of laryngeal granulomas. PATIENTS AND METHODS: Prospective series of 7 patients diagnosed of posterior laryngeal granuloma, 5 were male, and 2 female, ages ranging between 46 and 65 years, (only three with symptoms of gastroesophageal reflux), who followed an antireflux protocol (recommendations, omeprazol 20 mg, cisapride 20 mg, almagato 4000 mg daily). RESULTS: All cases did well, showing complete healing of the larynx 60 days after the beginning of treatment. CONCLUSIONS: Gastroesophageal reflux is an important factor in the genesis of posterior laryngeal granulomas. It seems appropriate to start an antireflux regimen before surgery, which can be chosen for non responders or cases with severe respiratory symptoms, hoarseness, or for definitive diagnosis (AU)
Subject(s)
Middle Aged , Aged , Male , Female , Humans , Granuloma, Respiratory Tract , Laryngeal Diseases/drug therapy , Magnesium Hydroxide , Omeprazole , Prospective Studies , Cisapride , Antacids , Anti-Ulcer Agents , Carbonates , Aluminum Hydroxide , Gastroesophageal Reflux/drug therapyABSTRACT
An elderly woman had a history of hemimandibulectomy for mandibular ameloblastoma performed 24 years earlier. In the last follow-up visit, an excrescent and ulcerative lesion was detected in the posterior wall of the cavum, below and medial to Rosenmüller's fossa, with clamps of enlarged, consistent cervical lymph nodes that was more marked on the right side. Cavum biopsy and needle biopsy of the lymph nodes revealed tuberculosis. This diagnosis usually is incidental and the differential diagnosis includes tumoral and granulomatous processes. Biopsy of the cavum is important for regional lesions with cervical lymph node enlargement.