ABSTRACT
Se realiza el estudio histopatológico de las lesiones que el paraquat produce en el hígado. El estudio microscópico de los 15 casos revisados indica el posible papel que la lesión del endotelio juega en el desarrollo de la lesión hepatotóxica producida este plaguicida
The aim of this study is to describe the histopathological characteristics of the liver damage in paraquat poisoning. The microscopic characteristics of the liver damage in the 15 cases reviewed emphasize the possible role of the endothelial lesions in the development and pathological expression of liver damage
Subject(s)
Male , Female , Humans , Paraquat/adverse effects , Paraquat/toxicity , Endothelium/injuries , Poisoning/mortality , Necrosis/complications , Hemorrhage/complications , Cholangitis/complications , Cholestasis, Extrahepatic/pathology , Cholestasis/complications , Cholestasis, Intrahepatic/complications , Liver/anatomy & histology , Liver/injuries , Necrosis/diagnosis , Cholangitis/diagnosis , Cholestasis/diagnosis , Cholestasis, Extrahepatic/complications , Liver/pathology , Toxicology/methods , Toxicology/statistics & numerical data , Hepatocytes/pathologyABSTRACT
The causes of sudden cardiac death are diverse and are function of age. In young people, coronary anomalies, hypertrophic cardiomyopathy are the most common findings at autopsies; in adults, coronary atherosclerosis and acquired forms of cardiomyopathy are frequent findings. In many of non-ischemia related cases autopsies are unrevealing. One of the most frustrating challenges is the inability to determine the cause of death in a person previously healthy. The majority of such sudden deaths are caused by acute ventricular tachyarrhythmias, but unfortunately unassociated with structural injury to the heart. The present work evaluates incidence, clinical data, and laboratory tests. Biochemical studies on serum, pericardial fluid, vitreous humour and pathological characteristics of 38 cases of sudden cardiac death from 2003 were investigated by us. Also, non-cardiac natural causes of death must be excluded.
