ABSTRACT
OBJECTIVE: To determine if DNA quantification on fine needle aspiration (FNA) has predictive value in breast cancer. STUDY DESIGN: Forty-nine patients with breast cancer were selected for this study because of their common characteristics. The smears were studied using image cytometry. RESULTS: With the type of histogram and value of entropy, two large groups, with high and low degrees of malignancy, were obtained. Survival was utilized as a variable of interest. Kaplan-Meier survival curves for both groups were formulated, and the results were supported with statistical data. CONCLUSION: The survival differences between both groups were statistically significant (P < .001), thus demonstrating the predictive value of DNA quantification.
Subject(s)
Breast Neoplasms/pathology , DNA, Neoplasm/analysis , Image Cytometry/methods , Biopsy, Needle , Breast Neoplasms/mortality , Coloring Agents , Disease Progression , Female , Hematoxylin , Humans , Ploidies , Predictive Value of Tests , Software , Survival RateABSTRACT
A case of renal angiomas, located on the tip of the papillae, presented with severe hematuria which required several blood transfusions. Radiological studies including arteriography were negative. The diagnosis was confirmed by intraoperative nephroscopy and histology.
