ABSTRACT
BACKGROUND: Interferon-associated retinopathy is a rare complication of interferon treatment. It has been well described with the use of interferon-α. METHODS: This study reports a retrospective case series of interferon-ß-associated retinopathy in three patients that were being treated for multiple sclerosis. RESULTS: All cases were characterized by cotton-wool spots or peripheral microaneurysms. One central retinal artery occlusion was observed associated with interferon-ß treatment. Findings improved spontaneously in two of three cases; all three patients elected to continue interferon treatment. CONCLUSION: Patients being treated with interferon-ß should have periodic fundus examinations to determine if they have evidence of interferon-associated retinopathy.
ABSTRACT
We report the updated results for a previously evaluated patient cohort who had uncemented total hip arthroplasties using the Lord femoral component. The original cohort consisted of 114 total hip arthroplasties (110 patients) performed from 1979 to 1984. The patients were followed up for an average of 21 years postoperatively. We describe the radiographic findings of 57 hips. At the last followup 11 (9.6%) of the 114 femoral components were revised or removed. Excluding infection there was an 83% 21-year survival according to Kaplan-Meier analysis. No significant radiographic changes occurred since the last publication. The prostheses are very well-fixed with no signs of loosening. Our current findings show the durability of the uncemented Lord femoral component indicating this prosthesis provides good long-term results.
