ABSTRACT
Apocrine hidrocystoma is a rare, benign, cystic tumor of the apocrine sweat glands. They are most commonly located around the eyes and may also be found on the scalp and neck. However, despite the fact that the nipple and areola contain numerous apocrine sweet glands, apocrine hydrocystomas have not been described previously in this area to the best of our knowledge. We report the first case of this cyst in this unsual location.
Subject(s)
Apocrine Glands/pathology , Nipples/pathology , Sweat Gland Neoplasms/pathology , Adult , Female , Humans , Nipples/diagnostic imaging , Sweat Gland Neoplasms/diagnostic imaging , Ultrasonography, MammarySubject(s)
Carcinoma, Squamous Cell/pathology , Keratoacanthoma/pathology , Skin Neoplasms/pathology , Tattooing , Adult , Cell Differentiation , Humans , MaleABSTRACT
El escleredema de Buschke se caracteriza por un engrosamiento de la dermis con depósito de mucina entre las fibras de colágeno, que se manifiesta como un endurecimiento de la piel, predominantemente en la mitad superior del tronco. Se ha relacionado con diabetes mellitus de larga evolución y mal controlada, gammapatías monoclonales e infecciones estreptocócicas. Se estudiaron los pacientes con el diagnóstico clínico de escleredema confirmado mediante estudio histopatológico y asociado a diabetes mellitus. Se revisaron las enfermedades asociadas, las características clínicas e histopatológicas, el curso evolutivo y la respuesta al tratamiento. El escleredema se caracteriza por un endurecimiento cutáneo que afecta a la mitad superior del tronco. En una gran proporción de casos se asocia a diabetes mellitus mal controlada, de curso prolongado durante años y con escasa respuesta al tratamiento
Scleredema of Buschke is characterized by a thickening of the dermis with mucin deposits among the collagen fibers, which manifests as a hardening of the skin, predominantly on the upper trunk. It has been associated with long-standing, poorly controlled diabetes mellitus, monoclonal gammopathies and streptococcus infections. We studied patients with a clinical diagnosis of scleredema confirmed by means of a histopathological study, and associated with diabetes mellitus. We reviewed associated diseases, clinical and histopathological characteristics, evolution and response to treatment. Scleredema is characterized by hardening of the skin, affecting the upper trunk. A large proportion of cases are associated with long-standing, poorly controlled diabetes mellitus, with little response to treatment
Subject(s)
Male , Female , Adult , Aged , Humans , Scleredema Adultorum/complications , Scleredema Adultorum/diagnosis , Scleredema Adultorum/therapy , Diabetes Mellitus/complications , Diabetes Mellitus/therapy , Scleredema Adultorum/pathology , Scleredema Adultorum/physiopathology , Diagnosis, Differential , BiopsyABSTRACT
Scleredema of Buschke is characterized by a thickening of the dermis with mucin deposits among the collagen fibers, which manifests as a hardening of the skin, predominantly on the upper trunk. It has been associated with long-standing, poorly controlled diabetes mellitus, monoclonal gammopathies and streptococcus infections. We studied patients with a clinical diagnosis of scleredema confirmed by means of a histopathological study, and associated with diabetes mellitus. We reviewed associated diseases, clinical and histopathological characteristics, evolution and response to treatment. Scleredema is characterized by hardening of the skin, affecting the upper trunk. A large proportion of cases are associated with long-standing, poorly controlled diabetes mellitus, with little response to treatment.
Subject(s)
Diabetes Complications , Scleredema Adultorum/etiology , Adult , Aged , Female , Humans , Male , Middle Aged , Scleredema Adultorum/pathologyABSTRACT
El xantogranuloma necrobiótico es una rara enfermedad granulomatosa que afecta a la piel y a otros tejidos, con frecuencia asociada a disproteinemia. Se presenta el caso de una paciente con sintomatología e histología de xantogranuloma necrobiótico que carecía de alteraciones en el proteinograma y de la típica afectación periocular. La paciente había sido diagnosticada recientemente de leucemia linfática crónica. El caso de nuestra paciente difiere de la mayoría de los descritos en la literatura especializada por asociarse a otro tipo de discrasia sanguínea y no tener afectación periocular. (AU)
Subject(s)
Female , Middle Aged , Humans , Leukemia, Lymphocytic, Chronic, B-Cell/complications , Granuloma/complications , Granuloma/diagnosis , Xanthomatosis/complications , Xanthomatosis/diagnosis , Necrobiotic Disorders/complications , Necrobiotic Disorders/diagnosis , Xanthomatosis/pathology , Necrobiotic Disorders/pathology , Granuloma/pathologyABSTRACT
Los siringomas son tumores benignos anexiales que se presentan como múltiples pápulas de color carne en cuero cabelludo, frente, cuello, parte anterior del tórax, axilas, mitad inferior del abdomen y extremidades. Su aparición en zona genital es infrecuente. Se desarrollan tras la pubertad, con mayor frecuencia en mujeres, y suelen ser asintomáticos. Se presenta el caso de una paciente de 19 años con siringomas, simétricos y bilaterales en la región vulvar (AU)
