ABSTRACT
No disponible
Subject(s)
Carotenoids , Bariatric Surgery/adverse effects , Dietary Supplements/adverse effects , Postoperative Complications , Vitamin A/adverse effectsABSTRACT
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Subject(s)
Humans , Female , Adult , Obesity, Morbid/surgery , Gastric Bypass , Fatty Liver/complications , Hypervitaminosis A/diagnosis , Postoperative Complications/epidemiologySubject(s)
Adrenal Insufficiency/chemically induced , Betamethasone/analogs & derivatives , Glucocorticoids/adverse effects , Substance Withdrawal Syndrome/etiology , Administration, Topical , Aged , Betamethasone/administration & dosage , Betamethasone/adverse effects , Glucocorticoids/administration & dosage , Humans , MaleSubject(s)
Antibodies, Monoclonal/adverse effects , Antineoplastic Agents/adverse effects , Brain Neoplasms/chemically induced , Brain Neoplasms/secondary , Breast Neoplasms/drug therapy , Breast Neoplasms/pathology , Carcinoma, Ductal, Breast/chemically induced , Carcinoma, Ductal, Breast/secondary , Meningeal Carcinomatosis/chemically induced , Meningeal Carcinomatosis/secondary , Receptor, ErbB-2 , Antibodies, Monoclonal, Humanized , Breast Neoplasms/chemistry , Fatal Outcome , Female , Humans , Middle Aged , Receptor, ErbB-2/analysis , TrastuzumabABSTRACT
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No disponible
Subject(s)
Humans , Female , Middle Aged , Antibodies, Monoclonal/adverse effects , Breast Neoplasms/drug therapy , Brain Neoplasms/secondary , Neoplasm Metastasis/drug therapy , Breast Neoplasms/complications , Brain Neoplasms/chemically inducedABSTRACT
A 48-year-old woman with a diagnosis of breast carcinoma was treated with adjuvant chemotherapy through a central venous catheter with subcutaneous reservoir (Port-A-Cath). While doxorubicin was administered, the patient presented thoracic pain and breathing distress due to superior vena cava perforation by the central catheter and subsequent extravasation of the drug into the mediastinum. The patient recovered without sequelae with conservative therapy. Cytostatic extravasation via central catheter is an uncommon complication in clinical practice. In this paper we present the first doxorubicin extravasation through a central catheter in adults and review the only ten cases found in the literature.