ABSTRACT
El síndrome del folículo vacío es una situación en la cual, repetidamente, no se recuperan ovocitos durante la punción-aspiración folicular. Existen 2 tipos de síndrome del folículo vacío: el falso y el genuino. Se presenta el caso clínico de una paciente de 38 años con esterilidad primaria de un año de evolución. Ante un estudio básico de esterilidad normal, se realizaron 4 ciclos de IAC, que resultaron fallidos. Se decidió realizar FIV-ICSI, llevándose a cabo un total de 3 ciclos; el primero, protocolo de estimulación con análogo largo, y los ciclos restantes, protocolo de estimulación con antagonista. En todos los casos se constató la ausencia de errores en la medicación y unos niveles de gonadotropina coriónica humana óptimos. Se llega al diagnóstico de síndrome del folículo vacío genuino, pues a pesar de obtener un desarrollo folicular y niveles adecuados de gonadotropina coriónica humana prepunción, no se obtienen ovocitos durante la misma. La ovodonación actualmente es la mejor alternativa
Empty follicle syndrome is a situation in which there is repeated failure to retrieve oocytes during follicular puncture-aspiration. There are 2 types of empty follicle syndrome: false and genuine. We report the case of a 38-year-old woman with a one-year history of primary sterility. After basic study of normal sterility, the patient underwent 4 unsuccessful artificial insemination cycles. We decided to carry out IVF-ICSI, and the patient underwent a total of 3 cycles. A long-agonist protocol was used in the first stimulation and an antagonist protocol in the remaining 2. In all stimulations, we confirmed the absence of medication errors and optimal levels of human chorionic gonadotropin. A diagnosis of genuine empty follicle syndrome was made because no oocytes were obtained during aspiration despite obtaining follicular development and appropriate levels of human chorionic gonadotropin pre-puncture. Oocyte donation is currently the best alternative
Subject(s)
Humans , Female , Adult , Infertility, Female/etiology , Oocyte Retrieval/methods , In Vitro Oocyte Maturation Techniques , Fertilization in Vitro , Chorionic Gonadotropin/analysis , Oocyte DonationABSTRACT
Endometrial cancer is diagnosed increasingly in young women who wish to have children, and treatments intended to preserve fertility in these patients are becoming more common. The authors describe two women with endometrial cancer who were diagnosed and treated at our center and who needed assisted human reproductive technology, and review current knowledge based on similar cases.
Subject(s)
Endometrial Neoplasms/physiopathology , Fertility Preservation , Adult , Endometrial Neoplasms/therapy , Female , HumansABSTRACT
Objetivo: Conocer el marco legal y científico, indicaciones, resultados, aspectos emocionales y controversias existentes relacionadas con la técnica de donación de ovocitos en reproducción asistida. Material y métodos: Revisión de las principales guías de práctica clínica publicadas en la bibliografía internacional (ESHRE, American Society for Reproductive Medicine, Royal College of Obstetricians and Gyneacologist [RCOG]). Resultados: La tasa de embarazo obtenida mediante esta técnica varía entre el 30 y 50% en función de las fuentes consultadas. La prestación asumida por el Servicio Andaluz de Salud sólo cubre el 17% de las indicaciones que se hacen en sanidad privada. Conclusiones: La donación de ovocitos es una técnica que obtiene buenos resultados en el segmento poblacional con peor pronóstico reproductivo. Su extensión difiere sustancialmente entre el sector privado y el público. Con la generalización de la técnica han aparecido nuevas controversias no del todo resueltas. El escaso número de donantes y los aspectos morales son los dos principales factores que limitan la extensión de la técnica (AU)
Objective: To determine the legal and scientific framework, indications, results, emotional issues, and current debates related to oocyte donation in assisted reproduction. Material and methods: We reviewed the main clinical practice guidelines published in the international literature (ESHRE, American Society for Reproductive Medicine, Royal College of Obstetricians and Gynecologists). Results: The pregnancy rate obtained by this technique varied between 30% and 50%, depending on the sources consulted. The services provided by the Andalusian Health Service covered only 17% of the indications covered by private health providers. Conclusions: Oocyte donation provides good results in the segment of the population with the worst reproductive prognosis. The use of this technique differs substantially between the private and public sectors. With the widespread use of this technique, new controversies have appeared that have not been entirely resolved. The two main factors limiting wider use of oocyte donation are the low number of donors and moral issues (AU)
Subject(s)
Humans , Female , Adult , Oocytes/physiology , Oocytes/transplantation , Oocyte Donation/methods , Menopause/physiology , Ovulation/blood , Ovulation/physiology , Ovulation Induction/instrumentation , Ovulation Induction/methods , Oocytes/classification , Oocyte Donation/statistics & numerical data , Oocyte Donation/trends , Oocyte Donation , Psychosocial ImpactABSTRACT
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