[Meal replacement as a dietary therapy for weight control. Assessment in males and females with different degrees of obesity]. / Sustitutivos de una comida como terapia dietética en el control de peso. Evaluación en hombres y mujeres con diferentes grados de obesidad.

Obesity is a metabolic disorder characterized by an increase in the fat in adipose tissue above certain limits, manifested by morphological alterations and excess weight. This condition is one of the most significant epidemics of this century due to over-eating and the ease of access to food. On the other hand, the direct relationship between obesity and the greater risk of suffering cardiovascular disease, diabetes or cancer means that consumers are demanding products, whether medicines or foodstuffs, that will allow them to overcome this situation and improve both their physical appearance and their health. The goal of this project was to identify the efficacy and safety of a dietary product, a meal replacement, within the setting of a balanced hypocaloric diet established for weight loss. To this end, a total of 47 volunteers of both sexes between the ages of 23 and 58, all employees of the Hero España, S.A. company, took part in a test in which eleven of them acted as the "control group" and ate only the low-calorie diet while the rest formed a "problem group" and replaced one meal (with a minimum of 500 calories) with a 200-calorie meal replacement. Participants were subjected to anthropometric measurements, blood pressure testing and a blood chemistry analysis before and after the test period, as well as to weekly weight checks. Those individuals with the highest Body Mass Index showed a greater weight loss than those with a lower index. The volunteers did not note any hunger pangs until three hours after consumption of the meal replacement and the health-status parameters analyzed did not show any anomalous values. Therefore, it is concluded that the replacement product studied allows controlled weight loss over 3 weeks when accompanied by a balanced low-calorie diet and it also produces a sensation of fullness in those consuming it.

Sustitutivos de una comida como terapia dietética en el control de peso. Evaluación en hombres y mujeres con diferentes grados de obesidad / Meal replacement as a dietary therapy for weight control. Assessment in males and females with different degrees of obesity

La obesidad es una enfermedad metabólica caracterizada por un aumento de la grasa del tejido adiposo por encima de ciertos límites, que se manifiesta por alteraciones morfológicas y sobrepeso. Esta enfermedad constituye una de las epidemias más importantes de este siglo, debido a la sobrealimentación y facilidad de acceso a los alimentos. Por otro lado, la relación directa entre la obesidad y el mayor riesgo de padecer enfermedades cardiovasculares, diabetes o cáncer, hace que el consumidor demande productos, ya sean alimenticios o fármacos, que le permitan superar esa situación y mejorar tanto su aspecto físico como su estado de salud. El objetivo de este proyecto fue conocer la eficacia y seguridad de un producto dietético, un sustitutivo de una comida, dentro del conjunto de una dieta hipocalórica equilibrada establecida para el control de peso. Para ello, se contó con la participación de 47 voluntarios, hombres y mujeres de 23 a 58 años, todos ellos pertenecientes a la plantilla de la empresa Hero España, S. A. Once de ellos actuaron de "grupo de control" e ingirieron la dieta hipocalórica únicamente, mientras que el resto o "grupo problema" sustituyó una de las comidas del día (mínimo de 500 calorías) por un sustitutivo de unas 200 calorías. Se les realizaron medidas de antropometría, tensión arterial y bioquímica sanguínea antes y tras el período de estudio, así como control de peso semanal. Los individuos de mayor Índice de Masa Corporal mostraron una mayor reducción de peso que los de menor índice. Los voluntarios no apreciaron sensación de hambre hasta tres horas después de consumir el sustitutivo, y los parámetros analizados relativos al estado de salud no mos- traron ningún valor anómalo. Se concluye por tanto, que el producto sustitutivo estudiado permite una reducción de peso controlada durante 3 semanas, cuando se acompaña de una dieta hipocalórica equilibrada, y produce, además, sensación de saciedad en el consumidor (AU)

Obesity is a metabolic disorder characterized by an increase in the fat in adipose tissue above certain limits, manifested by morphological alterations and excess weight. This condition is one of the most significant epidemics of this century due to over-eating and the ease of access to food. On the other hand, the direct relationship between obesity and the greater risk of suffering cardiovascular disease, diabetes or cancer means that consumers are demanding products, whether medicines or foodstuffs, that will allow them to overcome this situation and improve both their physical appearance and their health. The goal of this project was to identify the efficacy and safety of a dietary product, a meal replacement, within the setting of a balanced hypocaloric diet established for weight loss. To this end, a total of 47 volunteers of both sexes between the ages of 23 and 58, all employees of the Hero España, S.A. company, took part in a test in which eleven of them acted as the "control group" and ate only the low-calorie diet while the rest formed a "problem group" and replaced one meal (with a minimum of 500 calories) with a 200-calorie meal replacement. Participants were subjected to anthropometric measurements, blood pressure testing and a blood chemistry analysis before and after the test period, as well as to weekly weight checks. Those individuals with the highest Body Mass Index showed a greater weight loss than those with a lower index. The volunteers did not note any hunger pangs until three hours after consumption of the meal replacement and the health-status parameters analyzed did not show any anomalous values. Therefore, it is concluded that the replacement product studied allows controlled weight loss over 3 weeks when accompanied by a balanced low-calorie diet and it also produces a sensation of fullness in those consuming it (AU)

[Combined endoscopic and microscopic technique for naso-sinusal surgery]. / Técnica de la cirugía nasosinusal microscópica y endoscópica combinadas.

As an alternative method to endoscopic endonasal surgery of the paranasal sinuses the authors present their technique based on the use of a microscope with the help of a 25 degrees-30 degrees rigid endoscope to visualize anatomic sites which cannot be reached by microscope. This technique is called "Combined endonasal microsurgery" (CENM). Aspects of the anesthesia and the surgical procedure are discussed. With the combined technique described the goals of the endoscopic endonasal surgery may be achieved as well, being especially interesting for cases with large naso-sinusal polyposis.

[Surgery and radiotherapy in esthesioneuroblastoma of the nose, apropos of 2 cases]. / Cirugía y radioterapia en el estesioneuroblastoma olfatorio, a propósito de dos casos.

The esthesioneuroblastoma is a rare tumor localized in nose and sinus with difficult diagnosis (aspect like undifferentiated carcinoma and lymphosarcoma) local malignant. We have 2 cases in our hospital whose treatment and evolution is good. We have revised the diagnosis and treatment in these diseases.

[Mucous nasosinus melanoma. Apropos of a case]. / Melanoma mucoso nasosinusal. A propósito de un caso.

The mucous melanoma is a rare affection which has a very poor prognosis by its difficult diagnosis and unsatisfactory treatment. We have a patient with mucous melanoma nasal, which has been studied (clinic evolution, diagnosis and treatment) in our Hospital.