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2.
ASDC J Dent Child ; 46(5): 410-2, 1979.
Article in English | MEDLINE | ID: mdl-225360

ABSTRACT

Sleep apnea syndrome encompasses several entities that are characterized by the inability of the victim to achieve restful sleep. The only known treatment for the syndrome is a tracheostomy. Further research and experimentation are required. We are of the opinion that the appliance described in this article offers some promise as an alternative treatment.


Subject(s)
Apnea/therapy , Sleep Wake Disorders/therapy , Child , Dentures , Esophagus , Humans , Intubation/instrumentation , Sleep Stages , Sleep, REM
8.
Science ; 164(3879): 555-7, 1969 May 02.
Article in English | MEDLINE | ID: mdl-5778003

ABSTRACT

A spin filter device has been used for the propagation in vitro of cells of mnouse leukemia L1210 to densities approaching 10(8) cells per milliliter. By manipulation of flow rates, cells may be exposed to exponentially declining, drug concentrations with half-times of 1.5 hours or less, providing a more realistic parallel to in vivo drug treatment than is obtained by other culture methods.


Subject(s)
Culture Techniques/instrumentation , Filtration , Leukemia L1210 , Animals , Cell Line , Deoxyuridine/metabolism , Kinetics , Ligases/analysis , Methods , Mice , Models, Biological , Tetrahydrofolate Dehydrogenase/analysis , Thymidine/metabolism
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