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1.
Geriatr Orthop Surg Rehabil ; 12: 21514593211040293, 2021.
Article in English | MEDLINE | ID: mdl-34471569

ABSTRACT

Supervised, center-based, daily physiotherapy presents limitations: transport, need for an accompanying person, or risk of infection. Home-based rehabilitation protocols (HBRP) can be effective alternatives. We use a HBRP for the non-surgically treated proximal humeral fractures (PHF) in older patients. OBJECTIVES: To assess patient satisfaction and preferences of using a booklet, videos, or an app to guide physiotherapy. PATIENTS AND METHODS: Prospective, single-center observational study of patients ≥55 years old who sustained a non-surgically treated PHF. The HBRP consisted of immediate mobilization, followed by 5 physiotherapist-guided, weekly sessions of rehabilitation and standard physiotherapy after 3 months, if needed. A booklet with images, videos, or a smartphone application were offered to guide the patients. RESULTS: Mean degree of satisfaction (1-5) was 4.66 ± .9: 84 patients (82.4%) were very satisfied, 11 patients (10.8%) were satisfied, and 5 patients (4.9%) were not satisfied at all. Mean Oxford Shoulder Score achieved was 40.5 ± 6.6. 59.8% patients preferred the booklet and 29.4% the videos. Exercise compliance was considered very high in 87.3% of patients, while 4% hardly never followed the HBRP. Only 17.7% patients needed center-based physiotherapy after the HBRP. DISCUSSION: Reasons for satisfaction were good final functional outcome, no need for transportation, being away from hospital, immediate rehabilitation availability and being capable of maintaining independence. Adherence is a major concern. Videos are more didactic explaining the exercises. CONCLUSION: If standard physiotherapy is not available, the HBRP can be a valid treatment option for PHF management in older patients, with a high degree of patient satisfaction. Older patients preferred the booklet to guide physiotherapy.

2.
Geriatrics (Basel) ; 6(3)2021 Jun 29.
Article in English | MEDLINE | ID: mdl-34209613

ABSTRACT

Trapeziometacarpal osteoarthritis (TMCOA) is a highly prevalent disease in the older population. Many different types of surgical treatments are possible, depending on the degree of joint involvement, the personal and professional circumstances of the patient and the preferences of the orthopedic surgeon. This paper evaluated the clinical and radiological results of consecutive cohorts of patients over 65 years old treated with total joint arthroplasties (TJA) of the ball and socket type (B&S) for TMCOA, with a minimum of 10 years follow-up. The survival rate (Kaplan-Meier) of the functional prostheses at 10 years was 92.2% (95% CI (89.1%, 96.1%). These functional arthroplasty patients, after 10 years of follow-up, showed little or no pain, good function and good key pinch, without radiological alterations. TJAs of the B&S type are a long lasting, effective and reliable alternative to surgical treatment of TMCOA in patients over 65 years of age, when they are performed with the patient selection criteria and surgical technique described throughout this study.

3.
Geriatrics (Basel) ; 6(3)2021 Jun 30.
Article in English | MEDLINE | ID: mdl-34209013

ABSTRACT

Demand for total knee arthroplasty (TKA) in octogenarians will increase in subsequent years as society ages. We conducted a retrospective observational study in octogenarians operated on with TKA between 2015 and 2019, comparing preoperative and postoperative Knee Society Score (KSS), Knee Society Function Score (KSFS), extension and flexion balance, and radiologic alignment using a paired Student t-test. A chi-squared test was used to correlate mortality with Charlson comorbidities index score and with ASA scale. Kaplan-Meier analysis was performed to calculate patient survival. In this period 36 patients ≥80 years underwent TKA, with a mean age of 81.6 years. Of these, 24 patients (66.7%) were classified as ASA II and 12 (33.3%) as ASA III. Sixteen patients (44.4%) were Charlson 0, 14 (38.9%) Charlson 1, two (5.6%) Charlson 2, and four (11.1%) Charlson 3. KSS, KSFS, flexion and extension range, and radiologic alignment were statistically significant (p < 0.001) when comparing preoperatory and post-operatory data. No correlation (p > 0.05) was found between mortality and ASA or Charlson score. Seven patients (19.4%) suffered a medical complication and two patients experienced surgical complications. Four patient died (11.1%) during follow-up. The mean patient survival was 67.4 months. Patients ≥80 years achieve clinical improvement after TKA. Comorbidities, not age, are the burden for surgery in older patients.

5.
Nutrients ; 12(4)2020 Apr 01.
Article in English | MEDLINE | ID: mdl-32244696

ABSTRACT

BACKGROUND AND AIMS: Meal replacement diets consist of replacing one or more meals with an artificial nutritional supplement. The objective of this study was to compare the effect of one against two meal replacement strategies on body composition and cardiovascular risk parameters in patients with obesity. METHODS: A randomized clinical trial was designed with a modified hypocaloric diet with an artificial nutritional preparation replacing one or two meals for three months in patients with obesity and osteoarthritis pending orthopedic surgery. An anthropometric evaluation and a measurement of the body composition were done with bioelectrical impedance measurement at the beginning and at three months. RESULTS: A total of 112 patients were recruited. Fifty-two patients (46.4%) were randomized to one replacement and 60 patients (53.6%) to two meal replacements. Eighty-one patients (72.3%) were women, and the average age was 61 (11.03) years. The percentage of weight loss at three months was 8.27 (4.79)% (one meal replacement: 7.98 (5.97)%; two meal replacements: 8.50 (3.48)%; p = 0.56). A decrease in fat mass measured by the fat mass index (FMI) was detected (one meal replacement: -2.15 (1.45) kg/m2 vs. two meal replacements: -2.78 (2.55) kg/m2; p > 0.05), and a relative increase in fat-free mass was observed (one meal replacement: +3.57 (4.61)% vs. two meal replacements: +2.14 (4.45)%; p > 0.05). A decrease in HOMA-IR, systolic blood pressure (SBP), and total cholesterol was observed in both groups without differences between them. CONCLUSIONS: The substitution strategies of one or two meal replacements were effective in weight loss and fat mass decrease without differences between the two groups. An improvement in lipid parameters, glycemic control, and systolic blood pressure was observed without differences between strategies.


Subject(s)
Body Composition , Diet, Reducing , Dietary Supplements , Elder Nutritional Physiological Phenomena , Heart Disease Risk Factors , Meals , Obesity/diet therapy , Obesity/metabolism , Osteoarthritis/metabolism , Weight Loss , Aged , Cardiovascular Diseases , Female , Humans , Male , Middle Aged
6.
Micron ; 132: 102841, 2020 05.
Article in English | MEDLINE | ID: mdl-32062296

ABSTRACT

The histological study of hard pieces such as tendons and calcified lesions and tissues is a field that has been gaining increased attention owing to the rapid development of implantable prostheses, among other factors. In these studies, serial sectioning is utilized to detect areas of interest throughout the entire piece, as it enables the application of the appropriate light and electron microscopy techniques in these areas. We propose the "three-sectioning method" that subjects the pieces to three consecutive cycles of embedding and sectioning to localize and study the areas of interest, as an efficient technique for these histological studies. The pieces were first embedded in epoxy resin and then cut into thick sections (approximately 300 µm) for the first cycle. Next, areas of interest selected on these thick sections were re-embedded in epoxy resin to be sectioned again (second sectioning) to obtain a series of semithin sections (1-3 µm). These semithin sections are usually studied using the most relevant techniques for light microscopy. Smaller areas of interest are selected to be cut into ultrathin sections (60-90 nm) for transmission electron microscopy. If necessary, the selected areas of the semithin sections can be embedded again, and then cut into new ultrathin sections. The different kinds of sections we have described here may also be studied using scanning electron microscopy. This systematic method facilitates correlative microscopy from lower to higher magnifications along with the usage of a broad variety of histological techniques including electron microscopy.


Subject(s)
Histological Techniques/methods , Microscopy, Electron, Scanning , Microscopy, Electron, Transmission , Microtomy/methods , Specimen Handling/methods , Animals , Bone and Bones/ultrastructure , Epoxy Resins , Female , Male , Rats, Wistar , Tendons/ultrastructure
7.
J Hand Surg Eur Vol ; 45(5): 443-451, 2020 Jun.
Article in English | MEDLINE | ID: mdl-31495260

ABSTRACT

We report outcomes of 228 consecutive patients with total joint arthroplasty using the Arpe® prosthesis, among which 216 trapeziometacarpal joints in 199 patients had a minimum of 10 years follow-up. The cumulative survival rate of the 216 implants at 10 years using the Kaplan-Meyer method was 93%. Two hundred joints were functional and painless. We found good integration and positioning of the components in 184 (93%) of the joints. Sixteen prostheses failed. We conclude that this implant has acceptable long-term survival rate and restores good hand function. We also report our methods to improve implant survival and to decrease the risk of component malpositioning, and failure rate. Level of evidence: II.


Subject(s)
Arthroplasty, Replacement , Carpometacarpal Joints , Joint Prosthesis , Osteoarthritis , Carpometacarpal Joints/surgery , Follow-Up Studies , Humans , Osteoarthritis/surgery , Treatment Outcome
8.
Obes Res Clin Pract ; 13(4): 378-384, 2019.
Article in English | MEDLINE | ID: mdl-31006614

ABSTRACT

BACKGROUND: The choice of hypocaloric diets in obesity can affect bone health. AIMS: The aim of this study is to assess the effect of a hypocaloric diet in postmenopausal obese women and to determine the influence of weight reduction on bone metabolism. METHODS: This was a non-randomised, single-treatment study in 96 postmenopausal women with a body mass index (BMI) greater than 35kg/m2 and osteoarthritis. The patients received a formula diet with two intake levels of a normocaloric hyperproteic formula (1035kcal (25% protein)). Anthropometry and biochemistry with CrossLaps, osteocalcin, parathyroid hormone (PTH) and 25-OH vitamin D were measured. Consumption of protein, calcium and vitamin D were determined at the beginning of and 3 and 6 months into the study. The response to treatment was compared (high-responder (HR): weight loss greater than 15%, and low-responder (LR): weight loss less than 15%). RESULTS: The mean age was 64.2 (7.5) years. After 6 months of treatment, a weight loss of 10.2% (8.2-13.8) was observed. There was a significant increase in vitamin D (HR: 21.8% (36.2) vs. LR: 22.7% (36.9), p=0.93) and CrossLaps (HR: 26.8% (19.5-35.2)) vs. LR: 13.3% (-6.1 to 27.9), p=0.01). The loss of more than 15% of initial body weight was an independent risk factor for an increase in CrossLaps (OR: 4.22 (1.1-16.8), p=0.04). CONCLUSIONS: In postmenopausal obese women, weight loss was associated with an increase in the biochemical parameters of bone resorption. The increase in resorption parameters was related to the magnitude of weight loss.


Subject(s)
Bone Resorption/metabolism , Obesity/metabolism , Postmenopause/metabolism , Weight Loss/physiology , Bone Density Conservation Agents/administration & dosage , Bone Resorption/complications , Bone and Bones/metabolism , Calcium, Dietary/administration & dosage , Diet, Reducing , Female , Humans , Middle Aged , Obesity/complications , Obesity/diet therapy , Osteoarthritis, Hip/complications , Osteoarthritis, Hip/physiopathology , Osteoarthritis, Knee/complications , Osteoarthritis, Knee/physiopathology , Vitamin D/administration & dosage , Vitamin D/analogs & derivatives , Vitamin D/metabolism
9.
J Shoulder Elbow Surg ; 27(11): 2021-2029, 2018 Nov.
Article in English | MEDLINE | ID: mdl-29803503

ABSTRACT

BACKGROUND: Nonoperative management of proximal humeral fractures (PHFs) is the most common treatment, but its functional outcome may improve with early mobilization. In frail osteoporotic patients, quick recovery of prefracture independency is mandatory. This study assessed fracture displacement in PHFs managed with conservative treatment after early mobilization and a home-based self-exercise program. METHODS: We retrospectively analyzed the radiologic displacement of fracture fragments of PHFs treated conservatively with early mobilization and a home-based self-exercise program. RESULTS: Included were 99 patients with 26 one-part, 32 two-part, 32 three-part, and 9 four-part PHFs managed conservatively, followed by early mobilization and a home-based self-exercise program. In the x-ray examinations, the head displaced from varus into valgus 55° ± 23° to 42° ± 22°, in the normal range of anatomic values. The medial hinge displaced from medial to the diaphysis (+1 ± 6 mm) to lateral to the head (-0.6 ± 6 mm). The greater tuberosity displaced cranially from -1 ± 7 mm to 2 ± 5 mm. The Constant score at the 1-year follow-up was 79.69 ± 16.3. DISCUSSION AND CONCLUSIONS: The home-based self-exercise program for conservative treatment of PHFs displaces the head-diaphysis angle and the medial hinge toward anatomic reduction, but there is a risk of greater tuberosity cranial displacement. Functional results are fairly good, allowing frail patients to keep on with their independency and life style. Because a large number of patients might need further physiotherapy, the quality of the home-based self-exercises should be supervised.


Subject(s)
Conservative Treatment , Early Ambulation , Exercise Therapy , Home Care Services , Self Care , Shoulder Fractures/therapy , Aged , Aged, 80 and over , Diaphyses , Female , Humans , Male , Middle Aged , Radiography , Retrospective Studies , Shoulder Fractures/diagnostic imaging , Treatment Outcome
10.
Nutr Hosp ; 35(1): 71-77, 2018 Jan 16.
Article in English | MEDLINE | ID: mdl-29565152

ABSTRACT

BACKGROUND: Knee osteoarthritis is a disease with a high prevalence in our environment, especially in women. Weight loss can improve the quality of life of these patients before surgery. OBJECTIVES: To evaluate the effect of a meal-replacement diet on weight loss, body composition, and the improvement of the quality of life in obese women with knee osteoarthritis pending surgery. METHODS: One branch intervention study was performed over three months on 81 women with a body mass index greater than 30 kg/m2 with knee osteoarthritis before surgery. Patients received a hyperproteic meal-replacement diet with two bottles of an oral nutrition supplement in lunch and dinner (1,035 kcal). Anthropometric parameters, and body composition were measured. The quality of life was assessed by WOMAC and SF-36 test. RESULTS: The mean age of the patients was 62.23 (8.50) years. The percentage of weight loss was 8.23% (4.04). An improvement in the SF-36 total score was observed (basal: 49.35 [20.41], three months: 58.71 [17.07], p < 0.01). There was an improvement in WOMAC test (basal: 49.24% [25.53], three months: 40.59% [21.76], p < 0.01). It was observed that a 10% improvement in the SF-36 test was independently related to weight loss (OR: 1.2 [1.03-1.36], p < 0.02) adjusted by age and changes in body composition. CONCLUSIONS: In women with osteoarthritis of the knee treated with a meal-replacement diet, there is a significant decrease in weight and fat mass with a relative increase of the latter. There is an improvement in the quality of life according to SF-36 and WOMAC. There is an independent relationship between weight loss and SF-36 improvement.


Subject(s)
Diet, Reducing/psychology , Obesity/diet therapy , Obesity/psychology , Osteoarthritis, Knee/complications , Osteoarthritis, Knee/psychology , Aged , Aged, 80 and over , Arthroplasty, Replacement, Knee , Female , Humans , Middle Aged , Obesity/complications , Osteoarthritis, Knee/surgery , Quality of Life , Weight Loss
11.
Nutr. hosp ; 35(1): 71-77, ene.-feb. 2018. tab, graf
Article in English | IBECS | ID: ibc-172091

ABSTRACT

Background: Knee osteoarthritis is a disease with a high prevalence in our environment, especially in women. Weight loss can improve the quality of life of these patients before surgery. Objectives: To evaluate the effect of a meal-replacement diet on weight loss, body composition, and the improvement of the quality of life in obese women with knee osteoarthritis pending surgery. Methods: One branch intervention study was performed over three months on 81 women with a body mass index greater than 30 kg/m2 with knee osteoarthritis before surgery. Patients received a hyperproteic meal-replacement diet with two bottles of an oral nutrition supplement in lunch and dinner (1,035 kcal). Anthropometric parameters, and body composition were measured. The quality of life was assessed by WOMAC and SF-36 test. Results: The mean age of the patients was 62.23 (8.50) years. The percentage of weight loss was 8.23% (4.04). An improvement in the SF-36 total score was observed (basal: 49.35 [20.41], three months: 58.71 [17.07], p < 0.01). There was an improvement in WOMAC test (basal: 49.24% [25.53], three months: 40.59% [21.76], p < 0.01). It was observed that a 10% improvement in the SF-36 test was independently related to weight loss (OR: 1.2 [1.03-1.36], p < 0.02) adjusted by age and changes in body composition. Conclusions: In women with osteoarthritis of the knee treated with a meal-replacement diet, there is a significant decrease in weight and fat mass with a relative increase of the latter. There is an improvement in the quality of life according to SF-36 and WOMAC. There is an independent relationship between weight loss and SF-36 improvement (AU)


Introducción: la artrosis de rodilla es una enfermedad con alta prevalencia en nuestro medio, especialmente en mujeres. La pérdida de peso puede mejorar la calidad de vida de estas pacientes antes de la cirugía. Objetivos: evaluar el efecto de una dieta de sustitución de comidas en la pérdida de peso, la composición corporal y la mejora de la calidad de vida en mujeres obesas con artrosis de rodilla pendientes de cirugía ortopédica. Métodos: se realizó un estudio de intervención de una rama durante tres meses en 81 mujeres con un índice de masa corporal superior a 30 kg/m2 con artrosis de rodilla antes de la cirugía. Las pacientes recibieron una dieta de sustitución de comidas hiperproteica con dos botellas de un suplemento nutricional oral en almuerzo y cena (1.035 kcal). Se midieron los parámetros antropométricos y la composición corporal. La calidad de vida fue evaluada por WOMAC y la prueba SF-36. Resultados: la edad media de las pacientes fue de 62,23 (8,50) anos. El porcentaje de pérdida de peso fue de 8,23% (4,04). Se observó una mejora en la puntuación total del SF-36 (basal: 49,35% [20,41], tres meses: 58,71% [17,07], p < 0,01). Hubo una mejora en la prueba WOMAC (basal: 49,24% [25,53], tres meses: 40,59% [21,76], p < 0,01). Se observó que una mejora del 10% en la prueba SF-36 que se relaciono independientemente con la pérdida de peso (OR: 1,2 [1,03-1,36], p < 0,02) ajustada por edad y cambios en la composición corporal. Conclusiones: en mujeres con osteoartritis de la rodilla tratada con una dieta de sustitución de comidas hay una disminución significativa en el peso y la masa grasa, con un aumento relativo de esta última. Se observa una mejora en la calidad de vida según SF-36 y WOMAC y existe una relación independiente entre la pérdida de peso y la mejora del SF-36 (AU)


Subject(s)
Humans , Female , Overweight/diet therapy , Arthroplasty, Replacement, Knee/methods , Osteoarthritis, Knee/surgery , Obesity/complications , Diet, Reducing , Weight Loss/physiology , Preoperative Care/methods , Osteoarthritis, Knee/complications , Quality of Life , Risk Factors , Evaluation of Results of Therapeutic Interventions
12.
J Healthc Qual Res ; 33(2): 101-104, 2018.
Article in English | MEDLINE | ID: mdl-31610973

ABSTRACT

OBJECTIVES: The experience of students contributes to proactively identifying the changes necessary in training approaches and activities. The main objective of the Institutional Evaluation Programme was to design and validate a tool that permits discerning the experience of students from traumatology teaching. METHODS: Lecturers from the Orthopaedic Surgery Teaching Unit and experts in quality evaluation methodology, prepared the initial items. In this study, a descriptive analysis was carried out first, followed by an analysis of internal consistency and reliability, construction validity, and predictive validity. RESULTS: The results (Cronbach's alpha=0.58, Inter-Item Correlations >0.5, Eigenvalues >0.6, factor loadings, and the Student t-test values) confirmed its reliability and validity. CONCLUSIONS: The developed scale is reliable and valid to assess the experience of students. The use of a tool with these characteristics systematically contributes to improve teaching quality.

13.
Int Orthop ; 42(4): 859-866, 2018 04.
Article in English | MEDLINE | ID: mdl-29170879

ABSTRACT

AIM OF THE STUDY: The purpose of this study was to determine the recurrence rate, possible adverse reactions and factors influencing recurrence and progression of Dupuytren's disease (DD) treated with Collagenase from Clostridium histolyticum (CCH). METHOD: This was a prospective study of 71 patients with DD treated with CCH from 2011 to February 2013, with a minimum follow-up period of four years. Clinical, functional, patient satisfaction, drug safety and factors influencing recurrence and disease progression were evaluated. RESULTS: In all patients, the rupture of the cord was achieved after the injection, reducing joint contracture. In five patients (7%) we verified the existence of disease recurrence during the follow-up. In 11 patients (15.5%) there was a disease progression. Three patients have been surgically operated on, without added surgery difficulty; the rate of recurrence and progression was higher in grades III and IV of Tubiana, in proximal interphalangeal (PIP) punctures, and was earlier in patients younger than 60 years. DISCUSSION: No serious local complications or general complications were observed with this method. The recurrence of DD, following criteria of Felici, is mainly observed in young patients with greater severity of the disease and at the PIP level. Progression is influenced by the same factors. Patients operated on after recurrence have no added difficulty in the surgical technique, as it has also been published in other studies. CONCLUSIONS: Patients with the lowest rates of recurrence and progression were those with a single cord in the metacarpophalangeal (MCP), a grade II of Tubiana, and were older than 60 years.


Subject(s)
Dupuytren Contracture/therapy , Microbial Collagenase/adverse effects , Orthopedic Procedures/adverse effects , Postoperative Complications/epidemiology , Aged , Disease Progression , Dupuytren Contracture/complications , Female , Follow-Up Studies , Humans , Male , Microbial Collagenase/therapeutic use , Middle Aged , Orthopedic Procedures/methods , Patient Satisfaction/statistics & numerical data , Postoperative Complications/etiology , Prospective Studies , Recurrence , Risk Factors , Treatment Outcome
14.
Transplantation ; 101(8): 1945-1951, 2017 08.
Article in English | MEDLINE | ID: mdl-27661661

ABSTRACT

BACKGROUND: Degenerative disc disease often causes severe low-back pain, a public health problem with huge economic and life quality impact. Chronic cases often require surgery, which may lead to biomechanical problems and accelerated degeneration of the adjacent segments. Autologous mesenchymal stromal cells (MSC) treatments have shown feasibility, safety and strong indications of clinical efficacy. We present here a randomized, controlled trial using allogeneic MSC, which are logistically more convenient than autologous cells. METHODS: We randomized 24 patients with chronic back pain diagnosed with lumbar disk degeneration and unresponsive to conservative treatments into 2 groups. The test group received allogeneic bone marrow MSCs by intradiscal injection of 25 × 10 cells per segment under local anesthesia. The control group received a sham infiltration of paravertebral musculature with the anesthetic. Clinical outcomes were followed up for 1 year and included evaluation of pain, disability, and quality of life. Disc quality was followed up by magnetic resonance imaging. RESULTS: Feasibility and safety were confirmed and indications of clinical efficacy were identified. MSC-treated patients displayed a quick and significant improvement in algofunctional indices versus the controls. This improvement seemed restricted to a group of responders that included 40% of the cohort. Degeneration, quantified by Pfirrmann grading, improved in the MSC-treated patients and worsened in the controls. CONCLUSIONS: Allogeneic MSC therapy may be a valid alternative for the treatment of degenerative disc disease that is more logistically convenient than the autologous MSC treatment. The intervention is simple, does not require surgery, provides pain relief, and significantly improves disc quality.


Subject(s)
Bone Marrow Cells/cytology , Intervertebral Disc Degeneration/surgery , Lumbar Vertebrae , Mesenchymal Stem Cell Transplantation/methods , Mesenchymal Stem Cells/cytology , Adult , Feasibility Studies , Female , Follow-Up Studies , Humans , Intervertebral Disc Degeneration/diagnosis , Magnetic Resonance Imaging , Male , Pilot Projects , Prospective Studies , Quality of Life , Treatment Outcome
15.
Injury ; 47 Suppl 3: S22-S28, 2016 Sep.
Article in English | MEDLINE | ID: mdl-27692102

ABSTRACT

INTRODUCTION: The objectives of this study were to describe the surgical technique of fixation of 3-4 part proximal humeral fractures with polyaxial locking plates utilising a minimally invasive approach and to evaluate the accuracy of reduction and stability of fixation. PATIENTS AND METHODS: We retrospectively reviewed 90 patients. Fractures were classified according to the Neer classification system. Different radiological parameters were measured to assess the quality of reduction and the stability of fixation. Complications and clinical outcomes were evaluated after one year of minimum follow up. RESULTS: There were 76 women and 14 men, with a mean age of 67.4years ±13 (range, 29-85). There were 60 3-part and 30 4-part fractures. Frozen cancellous allograft was used in 30 cases (33.3%). All fractures progressed to union and at one year follow up, the mean Constant score was 79.6±12(range, 62-100). Mean forward flexion, abduction, external rotation and internal rotation were 155°, 148°, 39° and vertebra Dorsal 8, respectively. Complications were noted in seven patients while the postoperative "head-diaphysis angle", "greater tuberosity height" and "medial metaphysis reconstruction" were close to the anatomical parameters; no significant differences were noted at one year radiological follow up. CONCLUSION: Reliable and stable fixation can be expected with the use of polyaxial locking plate through a minimally invasive approach for the treatment of 3-4 part proximal humeral fractures. Satisfactory functional results for this procedure can be obtained.


Subject(s)
Fracture Fixation, Internal , Minimally Invasive Surgical Procedures , Shoulder Fractures/surgery , Adult , Aged , Aged, 80 and over , Bone Plates , Female , Follow-Up Studies , Fracture Healing , Humans , Male , Middle Aged , Pain Measurement , Radiography , Range of Motion, Articular , Retrospective Studies , Shoulder Fractures/diagnostic imaging , Shoulder Fractures/physiopathology , Spain , Treatment Outcome
16.
Acta Orthop Belg ; 81(2): 283-8, 2015 Jun.
Article in English | MEDLINE | ID: mdl-26280968

ABSTRACT

PURPOSE: Younger patients with unicompartmental degenerative knee joint diseases present a therapeutic dilemma. The purpose of this study is to evaluate the long-term results of the Oxford phase III unicompartmental knee replacement through a minimally invasive approach in the young patient. METHODS: We have studied a total of 51 patients (59 interventions) who underwent the Oxford Phase III Unicompartmental Knee Replacement. A clinical, radiographical and functional evaluation was performed twelve years after intervention. RESULTS: According to the American Knee Society Score using Insall's criteria overall results of unicompartmental knee arthroplasty showed an excellent or good outcome for 53 knees (96.36%), fair for 1 (1.81%) and poor for 1 (1.81%) in the postoperative long term. The survival rate of the implants was close to 95% at follow-up. CONCLUSIONS: Twelve years follow-up results of UKA through a minimally invasive exposure in young patients demonstrate predictably good outcomes.


Subject(s)
Arthroplasty, Replacement, Knee/methods , Knee Joint/physiopathology , Knee Prosthesis , Osteoarthritis, Knee/surgery , Adult , Female , Follow-Up Studies , Humans , Knee Joint/surgery , Male , Middle Aged , Osteoarthritis, Knee/diagnostic imaging , Osteoarthritis, Knee/physiopathology , Postoperative Period , Prognosis , Radiography , Retrospective Studies , Treatment Outcome , Young Adult
17.
Transplantation ; 99(8): 1681-90, 2015 Aug.
Article in English | MEDLINE | ID: mdl-25822648

ABSTRACT

BACKGROUND: Osteoarthritis is the most prevalent joint disease and a common cause of joint pain, functional loss, and disability. Conventional treatments demonstrate only modest clinical benefits without lesion reversal. Autologous mesenchymal stromal cell (MSC) treatments have shown feasibility, safety, and strong indications for clinical efficacy. We performed a randomized, active control trial to assess the feasibility and safety of treating osteoarthritis with allogeneic MSCs, and we obtain information regarding the efficacy of this treatment. METHODS: We randomized 30 patients with chronic knee pain unresponsive to conservative treatments and showing radiological evidence of osteoarthritis into 2 groups of 15 patients. The test group was treated with allogeneic bone marrow MSCs by intra-articular injection of 40 × 10(6) cells. The control group received intra-articular hyaluronic acid (60 mg, single dose). Clinical outcomes were followed for 1 year and included evaluations of pain, disability, and quality of life. Articular cartilage quality was assessed by quantitative magnetic resonance imaging T2 mapping. RESULTS: Feasibility and safety were confirmed and indications of clinical efficacy were identified. The MSC-treated patients displayed significant improvement in algofunctional indices versus the active controls treated with hyaluronic acid. Quantification of cartilage quality by T2 relaxation measurements showed a significant decrease in poor cartilage areas, with cartilage quality improvements in MSC-treated patients. CONCLUSIONS: Allogeneic MSC therapy may be a valid alternative for the treatment of chronic knee osteoarthritis that is more logistically convenient than autologous MSC treatment. The intervention is simple, does not require surgery, provides pain relief, and significantly improves cartilage quality.


Subject(s)
Bone Marrow Transplantation , Cartilage, Articular/surgery , Knee Joint/surgery , Mesenchymal Stem Cell Transplantation , Osteoarthritis, Knee/surgery , Adult , Aged , Bone Marrow Transplantation/adverse effects , Cartilage, Articular/pathology , Disability Evaluation , Female , Humans , Injections, Intra-Articular , Knee Joint/pathology , Magnetic Resonance Imaging , Male , Mesenchymal Stem Cell Transplantation/adverse effects , Middle Aged , Osteoarthritis, Knee/diagnosis , Osteoarthritis, Knee/physiopathology , Pain Measurement , Quality of Life , Spain , Time Factors , Transplantation, Homologous , Treatment Outcome
18.
Int Orthop ; 38(10): 2129-35, 2014 Oct.
Article in English | MEDLINE | ID: mdl-25038972

ABSTRACT

PURPOSE: Our purpose is to describe the results obtained in surgical treatment of a series of patients with symptoms of radial tunnel syndrome. METHODS: We performed a prospective study on 42 patients (43 limbs) operated for radial tunnel syndrome between 1996 and 2010, using a posterior-external approach. RESULTS: Using the Roles and Maudsley criteria, 21 patients had excellent results (48.8%), 16 good (37.2%) and six fair results (13.9%). Most patients were satisfied with the surgery, reporting symptom relief and improved functionality. CONCLUSIONS: Radial tunnel syndrome consists of intermittent compression of the posterior interosseous nerve in the forearm, with pain and functional disability of the forearm, without motor or sensory electromyogram alterations. Because it is often confused with enthesitis of the epicondyle muscle insertions (an entity often occurring simultaneously), differential diagnosis is necessary with treatment-resistant epicondylitis. The most effective treatment is surgical, releasing all possible nerve compression sites.


Subject(s)
Decompression, Surgical/methods , Nerve Compression Syndromes/surgery , Radial Neuropathy/surgery , Adult , Female , Humans , Male , Middle Aged , Prospective Studies , Young Adult
19.
Int J Surg Case Rep ; 4(10): 929-32, 2013.
Article in English | MEDLINE | ID: mdl-24012576

ABSTRACT

INTRODUCTION: Restoration of thumb function with a painfree, stable, and mobile joint with preserved strength are the main goals of treatment of painful arthritis of the thumb. We present our clinical experience in surgical treatment of this disease, in its highest degree of affectation. PRESENTATION OF CASE: A 57-year-old woman presents with a 2-year history of worsening pain at the base of her right, dominant, trapezial-metacarpal (TM) joint. Her thumb metacarpophalangeal (MCP) joint hyperextends 30° with lateral pinch. Radiographs demonstrate Eaton stage IV degenerative changes of her TM joint and no arthritis of her thumb MCP joint. She was successfully treated with a modified Burton-Pellegrini arthroplasty and sesamoidesis to the metacarpal head. DISCUSSION: In cases of advanced rhizarthrosis conventional surgery does not serve to correct deformities of the metacarpophalangeal joint that may affect to the postsurgical outcomes. CONCLUSION: rhizarthrosis management must be carried out in a global way. When a surgical treatment is planned, all deformities must be taken into account.

20.
Int Orthop ; 37(9): 1799-803, 2013 Sep.
Article in English | MEDLINE | ID: mdl-23722318

ABSTRACT

PURPOSE: The current trend in hallux valgus surgery is directed toward percutaneous procedures. However, no evidence that any of these methods of treatment are superior to the others has been described, excepting studies in the long term. The aim of this study was to analyse a series of patients who had undergone a percutaneous distal retrocapital osteotomy of the first metatarsal, and had been followed up for ten years. METHODS: We carried out a clinical and radiological evaluation of 115 feet ten years after surgery. RESULTS: The AOFAS scale results in the tenth postoperative year remained significantly favourable compared to their corresponding values in the preoperative period, yielding an improvement of 42.2 points overall on average. In relation to radiological findings, the mean hallux angle was maintained below 20 °, with a mean intermetatarsal angle of 8.1 °. CONCLUSION: Percutaneous retrocapital metatarsal osteotomy for treatment of mild to moderate hallux valgus is effective in the long term, with the advantages of a minimally invasive procedure.


Subject(s)
Hallux Valgus/surgery , Metatarsal Bones/surgery , Osteotomy/methods , Adult , Female , Follow-Up Studies , Humans , Male , Middle Aged , Pain Measurement , Recovery of Function , Treatment Outcome
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