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7.
Clin Nucl Med ; 45(3): e148-e150, 2020 Mar.
Article in English | MEDLINE | ID: mdl-31977466

ABSTRACT

We present the case of a 69-year-old man with history of prostate carcinoma treated with prostatectomy and subsequently with external beam radiotherapy and hormone therapy because of biochemical recurrences. More than 10 years after the diagnosis, follow-up Tc-HDP bone scans and SPECT/CT images demonstrated an incidental diagnosis of osteoblastic pleural plaques that quickly evolve to mesothelioma. PET/CT achieved the definitive diagnosis by guiding the biopsy to the highest and most accessible focus of glucidic hypermetabolism. Our case report raises the association between prostate cancer patients treated with external beam radiotherapy and the development of pleural mesothelioma despite having no history of exposure to asbestos.


Subject(s)
Lung Neoplasms/diagnostic imaging , Mesothelioma/diagnostic imaging , Pleural Neoplasms/diagnostic imaging , Positron Emission Tomography Computed Tomography , Prostatic Neoplasms/complications , Single Photon Emission Computed Tomography Computed Tomography , Aged , Diphosphonates , Fluorodeoxyglucose F18 , Humans , Lung Neoplasms/complications , Male , Mesothelioma/complications , Mesothelioma, Malignant , Organotechnetium Compounds , Pleural Neoplasms/complications , Prostatic Neoplasms/blood , Radiopharmaceuticals
18.
Clin Nucl Med ; 43(12): 939-940, 2018 Dec.
Article in English | MEDLINE | ID: mdl-30325823

ABSTRACT

We present a 44-year-old woman with scapular and pelvic muscle weakness, joint inflammation, and fever. Bone scintigraphy showed high uptake in proximal regions of upper and lower limbs, suspecting inflammatory myopathy and polyarticular damage. These features were the clue to request other complementary tests such as anti-aminoacyl-tRNA-synthetase antibodies and chest CT, which showed interstitial lung disease, defining an antisynthetase syndrome. Therefore, BS allows an earlier diagnosis of inflammatory muscle disease and to identify the optimal site for muscle biopsy. BS is an important step to reach a prompt diagnosis of antisynthetase syndrome for establishing an early treatment.


Subject(s)
Bone and Bones/diagnostic imaging , Myositis/diagnostic imaging , Radionuclide Imaging , Adult , Antigens, CD , Antigens, Differentiation, T-Lymphocyte , Diphosphonates , Early Diagnosis , Female , Humans , Lectins, C-Type , Organotechnetium Compounds , Radiopharmaceuticals , Tomography, X-Ray Computed
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