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1.
Nucleic Acids Res ; 48(D1): D70-D76, 2020 01 08.
Article in English | MEDLINE | ID: mdl-31722421

ABSTRACT

The European Nucleotide Archive (ENA, https://www.ebi.ac.uk/ena) at the European Molecular Biology Laboratory's European Bioinformatics Institute provides open and freely available data deposition and access services across the spectrum of nucleotide sequence data types. Making the world's public sequencing datasets available to the scientific community, the ENA represents a globally comprehensive nucleotide sequence resource. Here, we outline ENA services and content in 2019 and provide an insight into selected key areas of development in this period.


Subject(s)
Computational Biology , Databases, Nucleic Acid , Genomics , Computational Biology/methods , Europe , Genomics/methods , Molecular Sequence Annotation , Software , User-Computer Interface , Web Browser
2.
Nucleic Acids Res ; 47(D1): D84-D88, 2019 01 08.
Article in English | MEDLINE | ID: mdl-30395270

ABSTRACT

The European Nucleotide Archive (ENA; https://www.ebi.ac.uk/ena), provided from EMBL-EBI, has for more than three decades been responsible for archiving the world's public sequencing data and presenting this important resource to the scientific community to support and accelerate the global research effort. Here, we outline ENA services and content in 2018 and provide an overview of a selection of focus areas of development work: extending data coordination services around ENA, sequence submissions through template expansion, early pre-submission validation tools and our move towards a new browser and retrieval infrastructure.


Subject(s)
Computational Biology/methods , Databases, Nucleic Acid , Genomics/methods , Europe , Genome , Humans , Molecular Sequence Annotation , Search Engine , Software , Transcriptome , User-Computer Interface , Web Browser
3.
Nucleic Acids Res ; 46(D1): D36-D40, 2018 01 04.
Article in English | MEDLINE | ID: mdl-29140475

ABSTRACT

For 35 years the European Nucleotide Archive (ENA; https://www.ebi.ac.uk/ena) has been responsible for making the world's public sequencing data available to the scientific community. Advances in sequencing technology have driven exponential growth in the volume of data to be processed and stored and a substantial broadening of the user community. Here, we outline ENA services and content in 2017 and provide insight into a selection of current key areas of development in ENA driven by challenges arising from the above growth.


Subject(s)
Databases, Nucleic Acid , Computational Biology , Databases, Nucleic Acid/trends , Europe , High-Throughput Nucleotide Sequencing , Humans , Information Storage and Retrieval , Internet , Molecular Sequence Annotation
4.
Nucleic Acids Res ; 45(D1): D32-D36, 2017 01 04.
Article in English | MEDLINE | ID: mdl-27899630

ABSTRACT

The European Nucleotide Archive (ENA; http://www.ebi.ac.uk/ena) offers a rich platform for data sharing, publishing and archiving and a globally comprehensive data set for onward use by the scientific community. With a broad scope spanning raw sequencing reads, genome assemblies and functional annotation, the resource provides extensive data submission, search and download facilities across web and programmatic interfaces. Here, we outline ENA content and major access modalities, highlight major developments in 2016 and outline a number of examples of data reuse from ENA.


Subject(s)
Databases, Nucleic Acid , Sequence Analysis, DNA , Sequence Analysis, RNA , Genomics , Internet , Molecular Sequence Annotation
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