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ACS Appl Bio Mater ; 6(7): 2690-2697, 2023 07 17.
Article in English | MEDLINE | ID: mdl-37369011

ABSTRACT

In this study, we produced bioinspired micro/nanotopography on the surface of poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP) films and demonstrated that these films display antibacterial properties. In the first step, structures that are found on the surface of a rose petal were copied on the surface of PVDF-HFP films. Following this, a hydrothermal method was used to grow ZnO nanostructures on top of this rose petal mimetic surface. The antibacterial behavior of the fabricated sample was demonstrated against Gram-positive Streptococcus agalactiae (S. agalactiae) and Gram-negative Escherichia coli (E. coli) as model bacteria. For comparison purposes, the antibacterial behavior of a neat PVDF-HFP film was also investigated against both bacterial species. The results show that the presence of rose petal mimetic structures on PVDF-HFP helped the material to display improved antibacterial performance against both S. agalactiae and E. coli compared to the antibacterial performance of neat PVDF-HFP. The antibacterial performance was further enhanced for samples that had both rose petal mimetic topography and ZnO nanostructures on the surface.


Subject(s)
Rosa , Zinc Oxide , Escherichia coli , Zinc Oxide/pharmacology , Anti-Bacterial Agents/pharmacology , Anti-Bacterial Agents/chemistry
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