ABSTRACT
OBJECTIVE: The purpose of this study was to evaluate the healing benefit provided by the antioxidant and antifibrotic properties of pentoxifylline-tocopherol or pentoxifylline-tocopherol-clodronate in combination therapy for osteoradionecrosis. STUDY DESIGN: We searched for relevant reports in PubMed by using a combination of "osteoradionecrosis" and the following keywords: "pentoxifillyne," "tocopherol," "vitamin E," or "clodronate." We considered articles in English or Spanish, with no limitations on the publication date. RESULTS: The combination of pentoxifylline plus tocopherol with or without clodronate was found to be effective for the treatment of mandibular osteoradionecrosis, although data were generally scarce and mostly came from retrospective case series. CONCLUSIONS: This drug therapy is well tolerated and could be promising for the treatment of mandibular osteoradionecrosis, but prospective randomized controlled clinical trials are needed for further clarification.
Subject(s)
Clodronic Acid/therapeutic use , Head and Neck Neoplasms/radiotherapy , Mandibular Diseases/drug therapy , Osteoradionecrosis/drug therapy , Pentoxifylline/therapeutic use , Tocopherols/therapeutic use , Drug Combinations , HumansABSTRACT
Angiolymphoid Hyperplasia with Eosinophilia (ALHE) is an atypical vascular tumour occurring primarily in the head and neck area, which must be distinguished from Kimura's disease. The lesions can appear as single or multiple grouped intradermal papules or subcutaneous nodules. We report a rare case of ALHE in a 57-year-old female with a large lesion of three nodules involving the right occipital artery which had a long term evolution and we treated it by surgical excision. The definitive histopathological diagnosis was ALHE. Our case report is accompanied by a discussion of clinical, radiological and histological features. Surgical excision with free margins is the treatment of choice but, even though ALHE is considered a benign condition, recurrence is common.
ABSTRACT
No disponible
Subject(s)
Humans , Male , Aged , Hyperostosis, Diffuse Idiopathic Skeletal/complications , Spinal Cord Compression/complications , Spinal Cord Compression , Odontoid Process/pathology , Odontoid Process , Constriction, Pathologic/surgery , Constriction, Pathologic , Magnetic Resonance Imaging/instrumentation , Magnetic Resonance Imaging/methods , Magnetic Resonance Spectroscopy/methodsABSTRACT
No disponible
Subject(s)
Humans , Male , Adult , Nose Neoplasms/pathology , Nose Neoplasms/surgery , Nose Neoplasms , Nasal Surgical Procedures/methods , Medical History Taking/methods , Preoperative Care , Magnetic Resonance Imaging , Ethmoid Sinus/pathology , Ethmoid SinusABSTRACT
No disponible
Subject(s)
Humans , Male , Mucocele/complications , Mucocele/surgery , Mucocele , Ethmoid Sinus/pathology , Ethmoid Sinus/surgery , Ethmoid Sinus , Mucocele/microbiology , Mucocele/physiopathology , Magnetic Resonance Imaging/methods , Tomography, Emission-Computed/methods , Diagnosis, DifferentialABSTRACT
BACKGROUND: Myositis Ossificans is a rare heterotopic bone formation within a muscle being the masticatory muscles exceptionally involved. In most cases there is a previous trauma, bearing in mind that there may be many other etiologies. CT scan and panoramic radiographs along with histological findings are essential diagnostic aids. CASE DESCIPTION: We report a rare case of MO of masseter muscle in 49 years-old woman after repetitive wisdom tooth infection with the discussion of clinical, radiological and histological features. CLINICAL IMPLICATIONS: MO is a rare disease of masticatory muscles being the masseter the most frequently affected. Wide surgical excision with free margins is the treatment of choice although close postoperative monitoring it's essential to avoid relapses. KEY WORDS: Myositis ossificans, myositis ossificans traumatica, masticatory muscles, masseter muscle, trauma.
ABSTRACT
BACKGROUND: Pain and sensory changes due to lingual nerve injury are one of the most common alterations that follow surgical removal of third molar. They are usually transient but other less common complications, such as the atrophy of fungiform papillae, have an uncertain prognosis. CASE DESCRIPTION: We report a case of a 34-year-old woman who presented a unilateral lingual atrophy of fungiform papillae after third molar extraction accompanied by severe dysesthesia that altered her daily life significantly during the following months and how this complication evolved over time. We conducted a literature review on the different factors that can lead to a lingual nerve injury. CLINICAL IMPLICATIONS: The clinical evolution of temporary and permanent somatosensitve injuries is an important fact to take into consideration during the postoperative management because it will indicate the lesion prognosis. Key words:Lingual nerve, third molar removal, somatosensitive alteration, papillae atrophy, permanent injury, temporary injury.
ABSTRACT
OBJECTIVES: Ghost cell odontogenic carcinoma is a rare condition characterized by ameloblastic-like islands of epithelial cells with aberrant keratinitation in the form of Ghost cell with varying amounts of dysplastic dentina. MATERIAL AND METHODS: We report a case of a 70 year-old woman with a rapid onset of painful swelling right maxillary tumor. Magnetic resonance showed a huge tumor dependent on the right half of the right hard palate with invasion of the pterygoid process and focally to the second branch of the trigeminal. Radiological stage was T4N0. The patient underwent a right subtotal maxillectomy with clear margins. Adjuvant radiotherapy was given. The patient was free of residual or recurrent disease 12 months after surgery. RESULTS: The tumor was 3,9cm in diameter. It was spongy and whitish gray. Microscopically the tumor was arranged in nets and trabeculae, occasionally forming palisade. Tumoral cells had clear cytoplasm with vesicular nuclei. There was atipia and mitosi with vascular and perineural invasion. The excised tumor was diagnosed as a GCOC. CONCLUSIONS: Ghost cell carcinoma is a rare odontogenic carcinoma. Its course is unpredictable, ranging from locally invasive tumors of slow growth to highly aggressive and infiltrative ones. Wide surgical excision with clean margins is the treatment of choice although its combination with postoperative radiation therapy, with or without chemotherapy, remains controversial. Key words:Ameloblastic carcinoma, calcifying odontogenic cyst, Ghost cell carcinoma, keratinizing epithelial odontogenic cyst, maxillary tumor, odontogenic carcinoma.
