[Clinical efficacy of combined anti-Helicobacter treatment of patients with duodenal ulcer]. / Klinicheskaia effektivnost' kombinirovannogo antikhelikobakternogo lecheniia bol'nykh iazvennoi bolezn'iu dvenadtsatiperstnoi kishki.

84 patients with duodenal ulcer and positive by Helicobacter pylori (HP) were divided into two groups. Group 1 consisted of 42 patients who received omeprasol, metranidasol and clarithromycin. Group 2 of 42 patients received rovamycin instead of clarythromycin. The results of the study show that anti-HP regimen with rovamycin is superior to clarythromycin by main criteria (percent of healed ulcers, HP eradication, time to remission, recurrence rate, side effects rate). Thus, three-component therapy of patients with recurrent duodenal ulcer maintains intragastric acidity optimal for fast healing of ulcer defect.