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NG-011 and NG-012, novel potentiators of nerve growth factor. I. Taxonomy, isolation, and physico-chemical and biological properties.

Ito, M; Maruhashi, M; Sakai, N; Mizoue, K; Hanada, K.

J Antibiot (Tokyo) ; 45(10): 1559-65, 1992 Oct.

Article in English | MEDLINE | ID: mdl-1473982

ABSTRACT

NG-011 and NG-012, novel potentiators of nerve growth factor (NGF), were isolated from the culture broth of Penicillium verruculosum F-4542, together with 3,4-dihydro-6,8-dihydroxy-3-methylisocoumarin. They potentiated the neurite outgrowth induced by NGF in rat pheochromocytoma cell line (PC12).

Subject(s)

Anti-Bacterial Agents/pharmacology , Lactones/pharmacology , Nerve Growth Factors/pharmacology , Neurites/drug effects , Penicillium , Phenols/pharmacology , Animals , Cells, Cultured , Coumarins/chemistry , Coumarins/isolation & purification , Coumarins/pharmacology , Isocoumarins , Lactones/chemistry , Lactones/isolation & purification , PC12 Cells , Penicillium/chemistry , Penicillium/classification , Penicillium/isolation & purification , Phenols/chemistry , Phenols/isolation & purification , Rats

[Role of dentistry in medical science. 2].

Maruhashi, M.

Shikai Tenbo ; 65(7): 1425-34, 1985 Jun.

Article in Japanese | MEDLINE | ID: mdl-3865404

Subject(s)

Dentistry/trends , Adult , Attitude to Health , Female , Humans , Oral Health , Toothbrushing

[Role of dentistry in medical science. 1].

Maruhashi, M.

Shikai Tenbo ; 65(5): 1009-16, 1985 May.

Article in Japanese | MEDLINE | ID: mdl-3865389

Subject(s)

Dentistry/trends , Feeding Behavior , Humans

[Ecological relation between diet and oral health].

Maruhashi, M.

Shikai Tenbo ; 62(6): 1189-96, 1983 Dec.

Article in Japanese | MEDLINE | ID: mdl-6582646

Subject(s)

Diet , Oral Health , Adult , Female , Humans , Middle Aged

[Effects of diet on health and periodontal diseases].

Maruhashi, M.

Shikai Tenbo ; 61(4): 763-74, 1983 Apr.

Article in Japanese | MEDLINE | ID: mdl-6575477

Subject(s)

Diet, Cariogenic , Periodontal Diseases/therapy , Adult , Female , Gingivoplasty , Humans , Male , Periodontal Diseases/diet therapy , Periodontal Diseases/etiology

[Research for the true healer. Influence of diet on health and periodontitis].

Maruhashi, M.

Shikai Tenbo ; 61(3): 531-48, 1983 Mar.

Article in Japanese | MEDLINE | ID: mdl-6573795

Subject(s)

Diet, Cariogenic , Periodontitis/prevention & control , Adult , Child , Health , Humans , Japan , Public Health Dentistry

Parasitic localization and growth in mongolian gerbil (Meriones ungulicutas) infected filarial Dipetalonema viteae under different lighting conditions.

Mizuno, F; Nogami, S; Maruhashi, M; Matsumura, T.

Kobe J Med Sci ; 28(4): 155-60, 1982 Aug.

Article in English | MEDLINE | ID: mdl-6891006

Subject(s)

Dipetalonema/isolation & purification , Gerbillinae/parasitology , Lighting , Animals , Dipetalonema Infections/parasitology , Female , Male

[Orthodontic management of adult patients in need of prosthetic treatment].

Maruhashi, M; Maruhashi, Y.

Shikai Tenbo ; Suppl: 243-51, 1980.

Article in Japanese | MEDLINE | ID: mdl-6932339

Subject(s)

Denture, Partial , Tooth Movement Techniques , Adult , Esthetics, Dental , Female , Humans , Middle Aged

[Orthodontic management of adult patients with periodontal diseases in need of prosthetic management].

Maruhashi, M; Maruhashi, Y.

Shikai Tenbo ; Suppl: 260-74, 1980.

Article in Japanese | MEDLINE | ID: mdl-6932341

Subject(s)

Periodontitis/therapy , Tooth Movement Techniques/methods , Adult , Denture, Partial , Female , Humans , Male , Root Canal Therapy

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